Genes News and Research

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Low dose of aspirin cuts recurrence risk in colorectal cancer with genetic mutation

A Swedish-led research team at Karolinska Institutet and Karolinska University Hospital has shown in a new randomized clinical trial that a low dose of the well-known medicine aspirin halves the risk of recurrence after surgery in patients with colon and rectal cancer with a certain type of genetic alteration in the tumor.

17 Sep 2025

New genetic test can help predict how people will respond to weight-loss medications

Mayo Clinic researchers have developed a genetic test that can help predict how people will respond to weight loss medications such as GLP-1s.

17 Sep 2025

Loss of key Y chromosome gene causes infertility in male mice

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to infertility and changes expression of hundreds of other important genes.

17 Sep 2025

Study reveals how ozone exerts multi-organ effects by disturbing the lung-liver connection

Ozone pollution is rising worldwide, frequently exceeding safety thresholds in urban centers and industrial regions. Its health risks are well-documented: breathing ozone can worsen asthma, damage airways, and increase the risk of cardiovascular and neurological disorders.

17 Sep 2025

High fat diet impairs memory formation through autophagy dysfunction

Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders.

17 Sep 2025

Special subgroup of bifidobacteria found to reduce antibiotic resistance in infants

Researchers from the Technical University of Denmark, DTU, document that a special subgroup of naturally occurring bifidobacteria plays a crucial role in reducing antibiotic resistance in infants.

17 Sep 2025

Dipeptides reveal clues to the origin of life’s instructions

Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function.

17 Sep 2025

GLP-1 drugs found to protect against diabetic retinopathy

GLP-1 receptor agonist drugs protect against diabetic retinopathy, a common complication of diabetes that can lead to sight loss, suggests new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published in the journal Pharmaceutics.

17 Sep 2025

CRISPR-GPT helps scientists to generate designs, analyze data and troubleshoot design flaws

Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments.

16 Sep 2025

Lymphatic vessels found to undergo dramatic changes during kidney transplant rejection

Scientists have uncovered how lymphatic vessels – the kidney's 'plumbing system' – undergo dramatic changes during chronic transplant rejection, becoming structurally disorganised and spreading to unusual parts of the kidney.

16 Sep 2025

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome.

16 Sep 2025

Novel biotechnical vector integrates viral and synthetic features for targeted cancer therapy

Gene therapy offers the possibility of addressing cancer at its molecular roots by targeting disease-causing genes rather than relying solely on surgery, chemotherapy, or radiotherapy.

16 Sep 2025

Boosting PI31 to restore synaptic function and prevent neurodegeneration

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail.

16 Sep 2025

Study reveals how centenarians preserve youthful immune defenses

Researchers mapped immune cells from centenarians, their offspring, and younger controls across three cohorts using multi-omics single-cell profiling. They found that centenarians retain leaner helper pools but have enhanced cytotoxic and NK cell programs, along with reinforced NK–T communication networks.

15 Sep 2025

BioDlink Commends Junshi Biosciences as its Bispecific ADC Candidate JS212 Receives IND Approval

BioDlink, a leading global CDMO, extends its congratulations to Junshi Biosciences, on receiving Investigational New Drug (IND) approval

From BioDlink 12 Sep 2025

Female-specific mechanism enhances heat production in brown fat

Higher activity of PGC-1α enables brown fat cells in females to thermogenic activity and energy expenditure compared to males, reveals a study conducted in Japan.

12 Sep 2025

AI toolset reveals links between lung fibrosis and aging

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 8, 2025, titled "AI-driven toolset for IPF and aging research associates lung fibrosis with accelerated aging."

11 Sep 2025

Breakthrough findings point to future treatments for juvenile dermatomyositis

Children with a rare, debilitating muscle disease could benefit from the findings of new research by experts at UCL and Great Ormond Street Hospital (GOSH).

11 Sep 2025

Study identifies C1orf122 as prognostic marker in liver cancer

Primary liver cancer is the third leading cause of cancer-related deaths, of which hepatocellular carcinoma (HCC) accounts for approximately 90% of all liver cancer cases.

11 Sep 2025

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

Weill Cornell Medicine has received a four-year, $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, for a study of the details and dynamics of the autoimmune process that causes type 1 diabetes.

11 Sep 2025

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Genes News and Research

Low dose of aspirin cuts recurrence risk in colorectal cancer with genetic mutation

New genetic test can help predict how people will respond to weight-loss medications

Loss of key Y chromosome gene causes infertility in male mice

Study reveals how ozone exerts multi-organ effects by disturbing the lung-liver connection

High fat diet impairs memory formation through autophagy dysfunction

Special subgroup of bifidobacteria found to reduce antibiotic resistance in infants

Dipeptides reveal clues to the origin of life’s instructions

GLP-1 drugs found to protect against diabetic retinopathy

CRISPR-GPT helps scientists to generate designs, analyze data and troubleshoot design flaws

Lymphatic vessels found to undergo dramatic changes during kidney transplant rejection

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

Novel biotechnical vector integrates viral and synthetic features for targeted cancer therapy

Boosting PI31 to restore synaptic function and prevent neurodegeneration

Study reveals how centenarians preserve youthful immune defenses

BioDlink Commends Junshi Biosciences as its Bispecific ADC Candidate JS212 Receives IND Approval

Female-specific mechanism enhances heat production in brown fat

AI toolset reveals links between lung fibrosis and aging

Breakthrough findings point to future treatments for juvenile dermatomyositis

Study identifies C1orf122 as prognostic marker in liver cancer

Weill Cornell Medicine receives $3.4 million NIH grant to study type 1 diabetes development

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