Genetic Engineering News and Research

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Scientists develop genetically engineered probiotic that targets and kills cancer cells in the gut

A new study has identified a way to turn a humble cocktail of bacteria and vegetables into a targeted system that finds and kills colorectal cancer cells.

11 Jan 2018

CHOP researchers explore effective nutritional therapies for mitochondrial disease

Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems.

10 Jan 2018

Impact of craniosacral therapy on concussion and mild TBI symptoms among football players

This invited commentary references a preliminary study in which the integrative medicine technique known as CranioSacral Therapy was tested on a group of ex-National Football League players who showed significant improvement in range of motion, pain, sleep, and cognitive function.

10 Jan 2018

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer's disease.

9 Jan 2018

ABM publishes new guidelines on informal breast milk sharing for healthy term infants

In response to the increasing informal sharing of human milk, the Academy of Breastfeeding Medicine has published guidelines to minimize the risk of this practice while enhancing the health benefits.

9 Jan 2018

Researchers discover why exercise is good and high blood pressure is bad for the heart

When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular Research and of Heidelberg University Hospital have obtained new findings which indicate that a previously undetected signal pathway causes or protects from heart failure - depending on the type of stress.

9 Jan 2018

Oncologists discover cell type that gives rise to soft tissue cancer in children

St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children.

8 Jan 2018

Researchers pinpoint mechanism for conversion of white fat into brown fat

An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat.

5 Jan 2018

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Acute chest syndrome (ACS), a potentially severe lung complication of sickle cell disease, increases a child's risk of respiratory failure, chronic lung disease, and prolonged hospitalization if not recognized early and treated effectively.

5 Jan 2018

Study identifies how excess fat disrupts heart cells' ability to produce energy

A University of Iowa study has identified how excess fat in the heart, a common feature in diabetes and obesity, can harm the cells' essential ability to produce energy.

5 Jan 2018

UC Davis expert expresses caution on genetically engineered HSCs

In a commentary published in the Jan. 4 issue of the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation.

4 Jan 2018

Powerful imaging technique sheds light on how the brain responds to vascular injury

Pericytes, a little-understood type of cell on the brain's blood vessels, grow into the empty space left when neighboring pericytes die, report researchers at the Medical University of South Carolina in a January 2nd, 2018 article in Cell Reports.

4 Jan 2018

'Thunder' protein activity may be associated with behavioral disorders like schizophrenia

Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain.

3 Jan 2018

Study suggests potential means of stalling or even reversing diabetes-related blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness.

3 Jan 2018

Advanced live cell imaging reveals brain’s response to blood vessel injury

Live cell imaging and laser beam ablation reveals the damage response of pericytes surrounding blood vessels in the brain.

3 Jan 2018

Japanese researchers propose new diagnostic criteria and treatment guidelines for thyroid storm

With a mortality rate estimated at 10%, the life-threatening condition known as thyroid storm (TS) demands rapid diagnosis and treatment and can benefit from new evidence-based guidelines for TS developed by researchers in Japan.

2 Jan 2018

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease.

26 Dec 2017

Specific diets may help prevent colorectal cancer in high-risk groups

Colorectal cancer is the most prevalent malignant tumor in Spain. It is known that factors such as diet and intestinal inflammation play an important role in its occurrence, but direct links between nutrients, inflammation and colorectal cancer are poorly described.

21 Dec 2017

Findings provide better understanding of thyroid hormones' role in mammalian seasonal changes

Researchers now have a better understanding of the role that thyroid hormones, the tissues that produce them, and the biochemical pathways on which they act have in driving seasonal reproduction in some mammals, and how this new information may help explain seasonal changes in metabolism and mood that affect humans.

21 Dec 2017

Dysfunctional gene may be cause of Crohn's disease in some patients

This holiday season, millions of people will gather at airports ready to board planes for destinations around the world. Depending on the environment at their destination, their suitcases may be filled with sunscreen and bathing suits, or heavy parkas and mittens.

19 Dec 2017

Genetic Engineering News and Research

Scientists develop genetically engineered probiotic that targets and kills cancer cells in the gut

CHOP researchers explore effective nutritional therapies for mitochondrial disease

Impact of craniosacral therapy on concussion and mild TBI symptoms among football players

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

ABM publishes new guidelines on informal breast milk sharing for healthy term infants

Researchers discover why exercise is good and high blood pressure is bad for the heart

Oncologists discover cell type that gives rise to soft tissue cancer in children

Researchers pinpoint mechanism for conversion of white fat into brown fat

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Study identifies how excess fat disrupts heart cells' ability to produce energy

UC Davis expert expresses caution on genetically engineered HSCs

Powerful imaging technique sheds light on how the brain responds to vascular injury

'Thunder' protein activity may be associated with behavioral disorders like schizophrenia

Study suggests potential means of stalling or even reversing diabetes-related blindness

Advanced live cell imaging reveals brain’s response to blood vessel injury

Japanese researchers propose new diagnostic criteria and treatment guidelines for thyroid storm

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

Specific diets may help prevent colorectal cancer in high-risk groups

Findings provide better understanding of thyroid hormones' role in mammalian seasonal changes

Dysfunctional gene may be cause of Crohn's disease in some patients

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