Immune Response News and Research

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Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Pioneering epigenome editing company Tune Therapeutics has announced it is working on a new and potentially curative approach to treating chronic HBV infection.

20 Nov 2023

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer.

17 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Assessing DDX53 as a potential early esophageal cancer antigen

A new research paper was published in Oncoscience (Volume 10) on November 10, 2023, entitled, "An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen."

17 Nov 2023

Promising new cancer therapy appears to be extremely potent against tuberculosis

A promising new cancer therapy also appears extremely potent against one of the world's most devastating infectious diseases: tuberculosis (TB).

16 Nov 2023

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

Study discovers that coffee, especially its bioactive compounds like chlorogenic acids, can inhibit SARS-CoV-2 entry and reduce ACE2 and TMPRSS2 levels, indicating that coffee intake might be a potential dietary strategy for COVID-19 prevention.

16 Nov 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

MOSAIC center aims to revolutionize glioblastoma treatment with image-based mathematical models

Mayo Clinic Comprehensive Cancer Center and Columbia University received a five-year, $10.6 million U54 center grant from the National Cancer Institute (NCI) to further study combining the molecular analysis of glioblastoma with MRI.

16 Nov 2023

Bacteria fight phages with RNA-based immune defense

There's no organism on earth that lives free of threat - including bacteria. Predatory viruses known as phages are among their most dire foes, infiltrating their cells to replicate and take over.

15 Nov 2023

Immune response that protects against infections also drives HIV latency

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

15 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide.

13 Nov 2023

Food allergies may be linked to increased cardiovascular death risk, study finds

Sensitivity to common food allergens such as dairy and peanuts could be an important and previously unappreciated cause of heart disease, new research suggests – and the increased risk for cardiovascular death includes people without obvious food allergies.

13 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

HMS immunologist unravels the mysteries of how the immune system communicates

The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks on the body, both internal and external.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

New study reveals link between autism brain states and early life memory retention

Neuroscientists have discovered a fascinating connection between the retention of early life memories and brain developmental trajectories associated with autism [Wednesday 8th November 2023].

8 Nov 2023

Immune Response News and Research

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Unraveling the immune system's response to nanoparticle drug delivery

Assessing DDX53 as a potential early esophageal cancer antigen

Promising new cancer therapy appears to be extremely potent against tuberculosis

Coffee and COVID: Study finds coffee inhibits SARS-CoV-2, offers new dietary defense strategy

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

MOSAIC center aims to revolutionize glioblastoma treatment with image-based mathematical models

Bacteria fight phages with RNA-based immune defense

Immune response that protects against infections also drives HIV latency

Study reveals mechanisms underlying non-suppressible HIV viremia

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Food allergies may be linked to increased cardiovascular death risk, study finds

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Preclinical research points to a promising new treatment option for pancreatic cancer patients

HMS immunologist unravels the mysteries of how the immune system communicates

Charting the future of IBD treatment: From immune modulators to microRNA therapies

New study reveals link between autism brain states and early life memory retention

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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