Immunization News and Research

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What childhood vaccine rates can, and can’t, teach us about Covid vaccines

Polls show Americans are increasingly interested in getting vaccinated against Covid-19, but such surveys are largely national, leaving a big question: When the vaccines become available to the general public, will enough people get it in your county, city or neighborhood to keep your community safe?

10 Mar 2021

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Viruses evolve under increased pressure, and new research from The Rockefeller University and University of Massachusetts Medical School in the U.S. suggests our antibodies can as well.

10 Mar 2021

Pfizer COVID-19 vaccine elicits antibodies in blood and breastmilk simultaneously, finds study

A new study adds to the sum of knowledge around this issue, showing a highly synchronized and rapid development of an antibody response in breast milk and serum, which reached stable levels around two weeks after the second dose of the vaccine was administered.

10 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).

8 Mar 2021

Data from Israel’s vaccination program suggests Pizer-BioNTech COVID-19 vaccine induces strong host antibody response

A team of scientists from Israel has recently evaluated the efficacy of an mRNA-based coronavirus disease 2019 (COVID-19) vaccine, BNT162b2, in inducing host humoral immune response. The findings reveal that the vaccine is capable of inducing strong anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody response and that the response varies significantly with age. The study is currently available on the medRxiv* preprint server.

8 Mar 2021

California’s vaccine appointment website has glitches. No surprise?

California rolled out a statewide covid vaccination website this week aiming to streamline the appointment process after months of criticism, but the site is riddled with its own snags, preventing many from signing up for shots.

5 Mar 2021

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

A recent study reports the safety and high efficacy of an adjuvanted vaccine candidate against SARS-CoV-2 and the complications of COVID-19.

5 Mar 2021

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

A new study reports positive outcomes from two new vaccine candidates. The research, led by Axel T. Lehrer from the University of Hawaii at Manoa, studied mice's immune response when administered the CoVaccine HT adjuvant with an insect-cell expressed SARS-CoV-2 spike protein ectodomain.

4 Mar 2021

Accidentally trashed, thawed or expired: reports of Covid vaccine spoilage

As the speed of covid vaccinations picks up, so do the reports of doses going to waste. And it’s more than just a handful at the end of the day because of a few appointment cancellations. Health officials are trying to rein in waste without slowing down vaccinations.

4 Mar 2021

Researchers to investigate COVID-19's disproportionate impact on long-term care residents and workers

Long-term care facilities have been disproportionately burdened by COVID-19, accounting for about 60% of COVID-19 deaths nationwide, 70% if retirement homes are included.

3 Mar 2021

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

A team of UK scientists has recently evaluated the effectiveness of the Pfizer (BNT162b2) and AstraZeneca (ChAdOx1) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both vaccines are effective in significantly reducing SARS-CoV-2 infection in older adults and providing long-term protection.

3 Mar 2021

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

A new study by researchers at Mahidol University in Bangkok, Thailand, reports a COVID-19 vaccine candidate called HexaPro in producing neutralizing antibodies against the SARS-CoV-2 spike protein in an animal model.

3 Mar 2021

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models.

2 Mar 2021

Experimental therapy delays viral rebound in SHIV-infected macaques

A recent preclinical study by U.S. Military HIV Research Program (MHRP) researchers showed that an experimental therapy combining a TLR7 agonist and two broadly neutralizing antibodies delayed viral rebound in SHIV-infected macaques after antiretroviral therapy (ART) interruption.

2 Mar 2021

Connecticut is doling out vaccines based strictly on age. It’s simpler, but is it fair?

With Covid vaccines expected to remain scarce into early spring, Connecticut has scrapped its complicated plans to prioritize immunizations for people under 65 with certain chronic conditions and front-line workers. Instead, the state will primarily base eligibility on age.

1 Mar 2021

Why Astrazeneca and J&J’s vaccines, in use the world over, are still on hold in America

The World Health Organization greenlighted emergency use of AstraZeneca and Oxford's covid-19 vaccine this month, following in the steps of the United Kingdom, the European Union and others, who are already injecting it as quickly as possible into the masses.

26 Feb 2021

Researchers propose new mechanism to promote access to COVID-19 vaccines

Although the value of vaccines for COVID-19 may seem obvious, government action and investment in vaccines have not been commensurate with the enormous scale of benefits they offer, argue Juan Camilo Castillo and colleagues in this Policy Forum.

26 Feb 2021

International cooperation is key to get equal access to COVID-19 vaccines

Almost 130 countries are yet to receive a single COVID-19 vaccine dose, as ten high-income countries secure the majority.

25 Feb 2021

Immunization News and Research

What childhood vaccine rates can, and can’t, teach us about Covid vaccines

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Pfizer COVID-19 vaccine elicits antibodies in blood and breastmilk simultaneously, finds study

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

Data from Israel’s vaccination program suggests Pizer-BioNTech COVID-19 vaccine induces strong host antibody response

California’s vaccine appointment website has glitches. No surprise?

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

Accidentally trashed, thawed or expired: reports of Covid vaccine spoilage

Researchers to investigate COVID-19's disproportionate impact on long-term care residents and workers

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Experimental therapy delays viral rebound in SHIV-infected macaques

Connecticut is doling out vaccines based strictly on age. It’s simpler, but is it fair?

Why Astrazeneca and J&J’s vaccines, in use the world over, are still on hold in America

Researchers propose new mechanism to promote access to COVID-19 vaccines

International cooperation is key to get equal access to COVID-19 vaccines

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