Immunization News and Research

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Which biomarkers can help predict severe COVID-19?

The ability to detect potentially fatal illness early on in the course of the disease would enable a swift prioritization of these high-risk individuals for treatment. A new preprint on the medRxiv* server presents an array of biomarkers that may help achieve this laudable goal.

15 Mar 2021

New vaccination method aims at comprehensive protection against all known influenza mutations

One shot, protected forever: This would be a dream come true regarding influenza vaccinations. So far, vaccination against influenza did not provide a lasting protection.

13 Mar 2021

Could horse-derived antibodies promote immunity against SARS-CoV-2 infection?

Researchers based in India have demonstrated that horses inoculated with an inactivated dosage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are able to produce large amounts of strong antibodies that can neutralize multiple variants

12 Mar 2021

Single-dose vaccines may provide sufficient immunization for individuals previously infected with SARS-CoV-2

A group of researchers based at the Papa Giovanni XXIII hospital in Italy have submitted evidence to suggest that individuals previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may adequately benefit from a single dose of mRNA vaccine, rather than requiring the current two-vaccine regimen.

12 Mar 2021

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

In a study published in the journal Drugs, a researcher tackled the approval of Pfizer-BioNTech’s COVID-19 vaccine, which has now been used in many countries.

12 Mar 2021

Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

Researchers in Spain have conducted the most extensive study to date investigating the effectiveness of vaccinating healthcare workers with a single dose of the Pfizer-BioNTech vaccine to protect against coronavirus disease 2019 (COVID-19).

11 Mar 2021

One in four people could face some degree of hearing loss by 2050, WHO report warns

One in four people across the world — nearly 2.5 billion — could face some degree of hearing loss by 2050 with at least 700 million requiring access to treatment and rehabilitation, a WHO report warns.

11 Mar 2021

Nanobody works against all SARS-CoV-2 variants of concern in animal model

Researchers based in Belgium have developed a new antibody drug that is highly successful at neutralizing coronavirus disease 2019 (COVID-19) in Syrian hamsters. The new biologic was administered to the rodents and was found to be equally successful at neutralizing the original severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain, and also the new mutant variants, such as the South African and UK strains.

11 Mar 2021

Danish study on the efficacy of Pfizer/BioNTech SARS-CoV-2 vaccine after first and second dose

As the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues, many countries have rolled out vaccines against the virus. In an encouraging preprint research paper posted to the medRxiv* server, scientists report on the vaccine efficacy in the Danish vaccination program.

10 Mar 2021

Mass immunization to stop Ebola outbreak in Guinea

As the first shipment of COVID-19 vaccines arrived in Africa this week, another vaccine was being rolled out in Guinea, in a bid to stop a fresh outbreak of Ebola in its tracks.

10 Mar 2021

What childhood vaccine rates can, and can’t, teach us about Covid vaccines

Polls show Americans are increasingly interested in getting vaccinated against Covid-19, but such surveys are largely national, leaving a big question: When the vaccines become available to the general public, will enough people get it in your county, city or neighborhood to keep your community safe?

10 Mar 2021

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Viruses evolve under increased pressure, and new research from The Rockefeller University and University of Massachusetts Medical School in the U.S. suggests our antibodies can as well.

10 Mar 2021

Pfizer COVID-19 vaccine elicits antibodies in blood and breastmilk simultaneously, finds study

A new study adds to the sum of knowledge around this issue, showing a highly synchronized and rapid development of an antibody response in breast milk and serum, which reached stable levels around two weeks after the second dose of the vaccine was administered.

10 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).

8 Mar 2021

Data from Israel’s vaccination program suggests Pizer-BioNTech COVID-19 vaccine induces strong host antibody response

A team of scientists from Israel has recently evaluated the efficacy of an mRNA-based coronavirus disease 2019 (COVID-19) vaccine, BNT162b2, in inducing host humoral immune response. The findings reveal that the vaccine is capable of inducing strong anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody response and that the response varies significantly with age. The study is currently available on the medRxiv* preprint server.

8 Mar 2021

California’s vaccine appointment website has glitches. No surprise?

California rolled out a statewide covid vaccination website this week aiming to streamline the appointment process after months of criticism, but the site is riddled with its own snags, preventing many from signing up for shots.

5 Mar 2021

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

A recent study reports the safety and high efficacy of an adjuvanted vaccine candidate against SARS-CoV-2 and the complications of COVID-19.

5 Mar 2021

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

A new study reports positive outcomes from two new vaccine candidates. The research, led by Axel T. Lehrer from the University of Hawaii at Manoa, studied mice's immune response when administered the CoVaccine HT adjuvant with an insect-cell expressed SARS-CoV-2 spike protein ectodomain.

4 Mar 2021

Immunization News and Research

Which biomarkers can help predict severe COVID-19?

New vaccination method aims at comprehensive protection against all known influenza mutations

Could horse-derived antibodies promote immunity against SARS-CoV-2 infection?

Single-dose vaccines may provide sufficient immunization for individuals previously infected with SARS-CoV-2

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

One in four people could face some degree of hearing loss by 2050, WHO report warns

Nanobody works against all SARS-CoV-2 variants of concern in animal model

Danish study on the efficacy of Pfizer/BioNTech SARS-CoV-2 vaccine after first and second dose

Mass immunization to stop Ebola outbreak in Guinea

What childhood vaccine rates can, and can’t, teach us about Covid vaccines

Neutralizing antibodies may be evolving to keep up with SARS-CoV-2 mutations

Pfizer COVID-19 vaccine elicits antibodies in blood and breastmilk simultaneously, finds study

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

Data from Israel’s vaccination program suggests Pizer-BioNTech COVID-19 vaccine induces strong host antibody response

California’s vaccine appointment website has glitches. No surprise?

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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