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Rare sex-specific brain cells found in male and female mice

Caltech researchers have discovered rare brain cell types that are unique to male mice and other types that are unique to female mice. These sex-specific cells were found in a region of the brain that governs both aggression and mating behaviors.

17 Oct 2019

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Since its invention during the Second World War for soldiers stationed in countries where malaria transmission rates were high, researchers have worked to pinpoint precisely how DEET actually affects mosquitos.

17 Oct 2019

Newly introduced BARseq technology can be used to expand the brain map

Cold Spring Harbor Laboratory Professor Anthony Zador has taken the next step in his quest to solve exactly how the brain is wired.

17 Oct 2019

Wistar receives major NIH grant to advance research on new melanoma targeted therapies

The Wistar Institute and collaborating institutions have received a major grant from the National Institutes of Health to further research on new melanoma targeted therapies integrating the role of the tumor microenvironment in influencing response to therapy and development of resistance.

17 Oct 2019

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

With a shared vision of accelerating genomic discovery and improving patient outcomes, leaders from Boston Children's Hospital, Children's Hospital of Philadelphia, and Cincinnati Children's Hospital came together in 2015 to form the Genomics Research and Innovation Network.

17 Oct 2019

Signaling defects could cause congenital heart condition

A congenital heart condition known as left ventricular non-compaction (LVNC) - which occurs when muscly projections in the embryonic heart fail to transform into compact heart muscle - could be caused by signaling defects, according to new preclinical research led by Duke-NUS Medical School in Singapore.

17 Oct 2019

Scientists successfully create age-resistant mice with hyper-long telomeres

Researchers have shown that it is possible to extend the life of mice by generating hyper-long telomeres, without using any gene modifying technologies.

17 Oct 2019

New drug treats inflammation related to inherited heart disease in young athletes

When young athletes experiences sudden cardiac death as they run down the playing field, it's usually due to arrhythmogenic cardiomyopathy, an inherited heart disease.

From Johns Hopkins Medicine 17 Oct 2019

Providers take many approaches to help support women and families after infant loss

For women who suffer the devastation of an infant loss during pregnancy, emotions can run the gamut. They may feel guilty, angry or even relieved. No matter the feeling, expressing those emotions plays a big role in adapting to life after such a tragic event.

17 Oct 2019

Substance use disorder can complicate postoperative valvular heart disease, shows study

Patients who suffer from infective endocarditis (IE) and struggle with substance use disorder (SUD) have a 240% increased risk of dying within 6 months to 5 years after valve surgery compared to other IE patients, according to a study published online today in The Annals of Thoracic Surgery.

17 Oct 2019

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease

Northwestern Medicine scientists have used patient-derived neurons to develop and test a new strategy to treat Parkinson's disease by mitigating the effects of harmful genetic mutations, as detailed in a study published today (Oct. 16) in Science Translational Medicine.

16 Oct 2019

Genes remember having low social status in the past

A new study in monkeys, published on October 14, 2019, in the Proceedings of the National Academy of Sciences, shows that organisms at the bottom of the social hierarchy live shorter lives. Moreover, they experience more sickness, and may continue to experience health problems despite moving up later. Adverse experiences of social life continue to reflect in their genes much longer than the actual experience, in the form of changes in gene expression via altered gene regulation.

16 Oct 2019

Improved antibody validation

Antibodies are used in a variety of clinical and research situations to examine the structure and function, and distribution of proteins. However, many researchers have found a lack of specificity in the functioning of these antibodies. This means that any work conducted using these antibodies will not yield reliable results.

16 Oct 2019

Pollution tied to silent miscarriage among pregnant women

Miscarriage happens when an embryo or fetus dies before the 20th week of pregnancy. In some cases, pregnant women experience silent miscarriage, also known as missed abortion. It happens when the fetus failed to develop or has died.

16 Oct 2019

Brain's neural activity plays a role in human aging, life span

The brain's neural activity - long implicated in disorders ranging from dementia to epilepsy - also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School.

16 Oct 2019

Study aims to find whether lifestyle changes may counteract a person's genetic risk for dementia

A new study at Rush University Medical Center aims to determine whether a combination of lifestyle changes can protect memory and thinking skills in people at risk of developing dementia.

16 Oct 2019

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

ALS patients with commonly inherited genetic variation may experience more severe symptoms

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two FDA-approved drugs to treat its progression and severity.

16 Oct 2019

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

The National Institutes of Health has awarded a Michigan State University researcher a $2.1 million, five-year grant to search vast databases of existing drugs.

16 Oct 2019

Epigenetic changes can lead to development of GISTs, other cancers

Most cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be effectively targeted with drugs that inhibit the activity of rogue cancer-promoting enzymes.

16 Oct 2019

Genetic News and Research

Rare sex-specific brain cells found in male and female mice

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Newly introduced BARseq technology can be used to expand the brain map

Wistar receives major NIH grant to advance research on new melanoma targeted therapies

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

Signaling defects could cause congenital heart condition

Scientists successfully create age-resistant mice with hyper-long telomeres

New drug treats inflammation related to inherited heart disease in young athletes

Providers take many approaches to help support women and families after infant loss

Substance use disorder can complicate postoperative valvular heart disease, shows study

Scientists use patient-derived neurons to develop new treatment strategy for Parkinson's disease

Genes remember having low social status in the past

Improved antibody validation

Pollution tied to silent miscarriage among pregnant women

Brain's neural activity plays a role in human aging, life span

Study aims to find whether lifestyle changes may counteract a person's genetic risk for dementia

Study reveals new and surprising function of adenine nucleotide translocator

ALS patients with commonly inherited genetic variation may experience more severe symptoms

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

Epigenetic changes can lead to development of GISTs, other cancers

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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