Protein C News and Research

RSS

A common compound in mouthwashes found to inhibit SARS-CoV-2 in vitro

Researchers found that cetylpyridinium chloride, found in most mouthwashes, lowers infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro, likely by inhibiting viral fusion with target cells. With more tests to prove validity, mouthwashes could be a simple, cheap way of curbing transmission.

24 Dec 2020

Study reveals the role of SETD2 protein in cancer cells, cell migration, and autophagy

SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell.

24 Dec 2020

New tool may help monitor serotonin transmission with greater fidelity than current methods

Serotonin is a neurochemical that plays a critical role in the way the brain controls our thoughts and feelings.

23 Dec 2020

At risk of extinction, black-footed ferrets get experimental COVID vaccine

In late summer, as researchers accelerated the first clinical trials of COVID-19 vaccines for humans, a group of scientists in Colorado worked to inoculate a far more fragile species.

23 Dec 2020

SARS-CoV-2 mutations may evade T cell immunity

A potentially disturbing new study suggests that SARS-CoV-2 may be undergoing strategic mutations that affect the host immune capacity to recognize and combat the pathogen via T effector cells.

23 Dec 2020

COVID-19 severity could be linked to genetic variance

A new study describes some potentially important genetic factors in the host that may shape the clinical symptoms and signs of the disease.

23 Dec 2020

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

A new study sheds light on some important differences between asymptomatic and symptomatic patients with coronavirus disease 2019 (COVID-19).

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Researchers discover protein that adjusts gene activity to match nutrient levels in roundworms

Transforming a fertilized egg into a fully functional adult is a complicated task. Cells must divide, move, and mature at specific times. Developmental genes control that process, turning on and off in a choreographed way.

23 Dec 2020

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

When a person has an infection, the body activates immune responses to fight it. IFNγ is an inflammatory molecule produced by the immune system that helps fight infections.

23 Dec 2020

New drug starves cancer cells by attacking mitochondria

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria.

22 Dec 2020

Surgery associated with better survival in metastatic breast cancer patients

Surgery, in addition to treatments like chemotherapy and radiation therapy, may increase the length of survival for metastatic breast cancer patients, according to Penn State College of Medicine and Penn State Cancer Institute researchers.

22 Dec 2020

Anti-diarrhea drug triggers cell death in glioblastoma cells

In cell culture, loperamide, a drug commonly used against diarrhea, proves effective against glioblastoma cells. A research team at Goethe University has now unraveled the drug’s mechanisms of action of cell death induction and – in doing so – has shown how this compound could help attack brain tumors that otherwise are difficult to treat.

22 Dec 2020

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Researchers have measured the antibody levels and types in hospitalized coronavirus disease 2019 (COVID-19) patients with different disease severity. Their results suggest gut immune pathways could play a role in reducing virus-based inflammation and recovery.

22 Dec 2020

Scientists isolate anti-COVID-19 nanobodies produced by a llama

National Institutes of Health researchers have isolated a set of promising, tiny antibodies, or "nanobodies," against SARS-CoV-2 that were produced by a llama named Cormac.

22 Dec 2020

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers of the "Cell Biology and Physiology-LABRET" group of the University of Malaga (UMA), together with the Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), have described a new genetic skeletal disorder based on a precision medicine strategy.

22 Dec 2020

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

An infant's odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate technique to examine the IRAK4 gene responsible for innate immunity.

22 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

Researchers have a promising lead on COVID-19 treatment

By taking a lesson from prostate cancer, researchers now have a promising lead on treatment for COVID-19. Two proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, M.D., Ph.D. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers. They also knew that TMPRSS2 was regulated by the androgen receptor.

21 Dec 2020

Study depicts previously unknown molecular mechanism underlying healthy brain development

A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain.

21 Dec 2020

Protein C News and Research

A common compound in mouthwashes found to inhibit SARS-CoV-2 in vitro

Study reveals the role of SETD2 protein in cancer cells, cell migration, and autophagy

New tool may help monitor serotonin transmission with greater fidelity than current methods

At risk of extinction, black-footed ferrets get experimental COVID vaccine

SARS-CoV-2 mutations may evade T cell immunity

COVID-19 severity could be linked to genetic variance

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers discover protein that adjusts gene activity to match nutrient levels in roundworms

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

New drug starves cancer cells by attacking mitochondria

Surgery associated with better survival in metastatic breast cancer patients

Anti-diarrhea drug triggers cell death in glioblastoma cells

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Scientists isolate anti-COVID-19 nanobodies produced by a llama

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

Study sheds new light on immune system interactions with cancer

Researchers have a promising lead on COVID-19 treatment

Study depicts previously unknown molecular mechanism underlying healthy brain development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News