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Researchers identify synergistic cellular pathways that considerably amplify lifespan

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research.

9 Jan 2020

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Pathios Therapeutics Limited, an innovative biotech company focused on the development of first-in-class therapies for autoimmune diseases and cancer, today announced a US$8.8M Series A financing round with leading international healthcare investors Canaan and Australia’s Medical Research Commercialization Fund managed by Brandon Capital.

9 Jan 2020

Diabetes drug could be repurposed as new treatment to prevent miscarriage

A drug designed to tackle diabetes could also be repurposed as the first treatment to prevent miscarriage by targeting the lining of the womb itself, according to a clinical trial led by the University of Warwick.

9 Jan 2020

New screening platform helped scientists to discover drug-like compounds

A sophisticated new screening platform developed by scientists at Scripps Research has enabled them to discover a set of drug-like compounds, including an ingredient found in sore throat lozenges, that may powerfully protect brain cells from dangerous stresses found in Alzheimer's and other neurodegenerative diseases.

9 Jan 2020

Study shows how sewage plants can remove pharmaceuticals from wastewater

Corals depend on their symbiotic relationships with the algae that they host. But how do they keep algal population growth in check?

9 Jan 2020

SVC112 molecule acts specifically against head and neck cancer stem cells

The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds.

8 Jan 2020

Study: Less than 2% of people at risk for opioid overdose are prescribed life-saving drug

Only a tiny minority of people at risk for an opioid overdose actually are prescribed a drug that could save their lives, a new study suggests. And the odds of having a dose of the rescue drug were very low among some of the most at-risk groups, including those who had already survived a previous opioid overdose.

8 Jan 2020

FSU discovery could open the door to new treatment options for HIV, hepatitis B

A discovery by Florida State University College of Medicine researchers is expected to open the door for new and more potent treatment options for many of the more than 36 million people worldwide infected with the HIV virus and for others chronically ill with hepatitis B.

8 Jan 2020

Researchers report first structural model for key enzyme associated with inherited eye diseases

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.

8 Jan 2020

UC Riverside research team receives NIH grant to study breast cancer

A research team led by biochemists at the University of California, Riverside, has received a four-year grant from the National Institutes of Health, or NIH, to study breast cancer -- the most common cancer in women worldwide -- and the racial disparities in the treatment of the disease.

8 Jan 2020

Researchers use single cell genome sequencing to study malaria transmission

New technology employing single cell genome sequencing of the parasite that causes malaria has yielded some surprising results and helps pave the way for possible new intervention strategies for this deadly infectious disease, according to Texas Biomedical Research Institute Assistant Professor Ian Cheeseman, Ph.D. Dr. Cheeseman was Principal Investigator of a three-year study published in the January 2020 edition of Cell Host & Microbe, a high-impact peer-reviewed publication.

8 Jan 2020

New hydrogel prevents and treats infections in wounds

Researchers at Lund University in Sweden have developed a new hydrogel based on the body's natural peptide defense.

8 Jan 2020

Researchers study the effects of antidepressants to identify the least harmful drugs

About one in ten women in Québec will suffer from depression during pregnancy. Without treatment, the illness carries risks for both mother and child.

8 Jan 2020

Two-drug combination could be effective against malignant mesothelioma

Exposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggressive cancer that mostly affects the pleura - the tissue that lines the lungs - and the peritoneum - the tissue that lines the abdomen. This has been known for decades, yet the molecular characterisation of mesothelioma is barely known and treatment options are scarce.

8 Jan 2020

Children with peripherally inserted central catheters are more likely to develop blood clots, study shows

A study has found that children inserted with PICCs are at higher risk of developing blood clots called venous thromboembolism.

8 Jan 2020

Research project leverages big data to close the gap on cognitive decline and healthy aging

A new research project at the University of Arizona Center for Innovation in Brain Science will apply a big-data approach, using bioinformatics and computational modeling, to better understand the systems biology of Alzheimer's and other neurodegenerative diseases.

8 Jan 2020

Heart transplants from hepatitis C–positive donors could help overcome organ shortage

One-year survival was similar for adults with severe heart failure who received a heart transplant from a donor with hepatitis C compared to those who received hearts from donors who did not have hepatitis C, according to new research published today in the Journal of the American Heart Association, the open access journal of the American Heart Association.

8 Jan 2020

5 things to know as California starts screening children for toxic stress

Starting this year, routine pediatric visits for millions of California children could involve questions about touchy family topics, such as divorce, unstable housing or a parent who struggles with alcoholism.

8 Jan 2020

A physically and mentally active lifestyle can slow familial frontotemporal dementia

A physically and mentally active lifestyle confers resilience to frontotemporal dementia (FTD), even in people whose genetic profile makes the eventual development of the disease virtually inevitable, according to new research by scientists at the UC San Francisco Memory and Aging Center.

8 Jan 2020

Use of antipsychotic drugs is linked to brain injuries in Alzheimer's patients

Use of antipsychotic medications was associated with an increased risk of head injuries in a study of individuals with Alzheimer's disease. The findings are published in the Journal of the American Geriatrics Society.

8 Jan 2020

Drugs News and Research

Researchers identify synergistic cellular pathways that considerably amplify lifespan

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Diabetes drug could be repurposed as new treatment to prevent miscarriage

New screening platform helped scientists to discover drug-like compounds

Study shows how sewage plants can remove pharmaceuticals from wastewater

SVC112 molecule acts specifically against head and neck cancer stem cells

Study: Less than 2% of people at risk for opioid overdose are prescribed life-saving drug

FSU discovery could open the door to new treatment options for HIV, hepatitis B

Researchers report first structural model for key enzyme associated with inherited eye diseases

UC Riverside research team receives NIH grant to study breast cancer

Researchers use single cell genome sequencing to study malaria transmission

New hydrogel prevents and treats infections in wounds

Researchers study the effects of antidepressants to identify the least harmful drugs

Two-drug combination could be effective against malignant mesothelioma

Children with peripherally inserted central catheters are more likely to develop blood clots, study shows

Research project leverages big data to close the gap on cognitive decline and healthy aging

Heart transplants from hepatitis C–positive donors could help overcome organ shortage

5 things to know as California starts screening children for toxic stress

A physically and mentally active lifestyle can slow familial frontotemporal dementia

Use of antipsychotic drugs is linked to brain injuries in Alzheimer's patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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