Genetic News and Research

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NIH-funded research consortium aims to advance treatments for frontotemporal lobar degeneration

The National Institutes of Health has awarded a five-year, multi-investigator research grant expected to total more than $63 million to Mayo Clinic and the University of California, San Francisco, to advance treatments for frontotemporal lobar degeneration

16 Oct 2019

Scientists decipher assembly line of glutamate receptors

Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian brain are glutamate receptors of the AMPA-type that generate the electrical signal required for fast communication between neurons.

16 Oct 2019

Scientists discover novel virus that may shed light on viral evolution

Viruses are non-living creatures, consisting of genetic material encased in a protein coat. Once the virus infects a living organism, it can replicate itself and continue on. But what happens if a virus lacks the proper tools to infect an organism? How can it propagate?

16 Oct 2019

UTEP awarded $19.2 million NIH grant to study cancer affecting Mexican-American population

The University of Texas at El Paso's Border Biomedical Research Center will accelerate its quest to understand and identify the reasons for Hispanic cancer health disparities and its ultimate impact on the people of the Paso del Norte region thanks to a five-year, $19.2 million grant from the National Institutes of Health.

16 Oct 2019

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

Scientists discover how malaria switched host from African gorillas to humans

Researchers have revealed the series of events that probably led to the world’s deadliest form of malaria being able to jump from ancient great apes to humans.

16 Oct 2019

Researcher explores biological processes that cause fertility problems in humans

With significant funding from the National Institutes of Health (NIH), a researcher at The University of Texas at Arlington is investigating fundamental biological processes that lead to fertility problems in humans.

16 Oct 2019

Study: Genetic differences in the immune system shape bacteria that colonize the digestive system

Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.

16 Oct 2019

New class of drugs could prevent cancer from becoming resistant to treatment

Scientists at Massey University in New Zealand have taken the first step towards a new class of drug that could stop cancer from becoming resistant to treatment. Treatment resistance is a serious problem to the successful treatment of cancer patients because it leads to cancer returning and becoming harder to treat.

15 Oct 2019

UCLA researchers discover new way to eliminate leukemia stem cells

The introduction of the drug imatinib in 2001 revolutionized the treatment of a type of cancer called chronic myelogenous leukemia. In more than 80% of people with CML who received the drug, the disease went into complete remission.

15 Oct 2019

PerkinElmer introduces PG-Seq Rapid Non-Invasive PGT-A kit as alternative to IVF embryo biopsies

PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today introduced its PG-Seq Rapid Non-Invasive Preimplantation Genetic Testing for Aneuploidy (PGT-A) kit. This solution tests spent embryo culture media for chromosomal abnormalities during in vitro fertilization treatment.

From Revvity 15 Oct 2019

Research reveals increased inflammatory activity in patients with frontotemporal dementia

Recent research from the University of Eastern Finland revealed increased inflammatory activity in a subgroup of patients with frontotemporal dementia. Increased inflammation was associated with parkinsonism symptoms and more rapid disease progression.

15 Oct 2019

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.

15 Oct 2019

Researchers reveal mechanism involved in altering DNA methylation in cancer

Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments and diagnosis. In this study, a multi-institutional team led by researchers at Baylor College of Medicine has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.

15 Oct 2019

Finnish study offers new information about molecular mechanisms of Alzheimer's disease

Researchers have discovered new changes in blood samples associated with Alzheimer's disease. A new international study was conducted on disease-discordant Finnish twin pairs: one sibling suffering from Alzheimer's disease and the other being cognitively healthy.

15 Oct 2019

New cancer treatment developed at Yale

Scientists at Yale have developed a method that assists the immune system in identifying and eliminating cancer cells that may be missed by other forms of immunotherapies.

15 Oct 2019

Risk of genetic seizure disorder: new scoring system

A Cleveland Clinic-led initiative has come up with a new risk scoring system for epileptic or seizure disorders of genetic origin. The researchers summed up the risks for a very large number of genes weakly implicated in some common forms of epilepsy, to create a polygenic risk score.

14 Oct 2019

Genetic News and Research

NIH-funded research consortium aims to advance treatments for frontotemporal lobar degeneration

Scientists decipher assembly line of glutamate receptors

Scientists discover novel virus that may shed light on viral evolution

UTEP awarded $19.2 million NIH grant to study cancer affecting Mexican-American population

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Scientists discover how malaria switched host from African gorillas to humans

Researcher explores biological processes that cause fertility problems in humans

Study: Genetic differences in the immune system shape bacteria that colonize the digestive system

New class of drugs could prevent cancer from becoming resistant to treatment

UCLA researchers discover new way to eliminate leukemia stem cells

PerkinElmer introduces PG-Seq Rapid Non-Invasive PGT-A kit as alternative to IVF embryo biopsies

Research reveals increased inflammatory activity in patients with frontotemporal dementia

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

Researchers reveal mechanism involved in altering DNA methylation in cancer

Finnish study offers new information about molecular mechanisms of Alzheimer's disease

New cancer treatment developed at Yale

Risk of genetic seizure disorder: new scoring system

The language of metabolites can be decoded with new genome technology

Custom-made oligonucleotide therapy for girl with fatal Batten disease

Cleveland Clinic-led researchers develop novel genetic-based epilepsy risk scores

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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