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Study provides better understanding of mechanisms that limit cilia number in cells

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes.

30 Dec 2019

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Combination treatment reduces breast cancer development in mice

Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy.

30 Dec 2019

A new deep learning approach to predict disease-associated mutations

During the past years, artificial intelligence (AI) -- the capability of a machine to mimic human behavior -- has become a key player in high-techs like drug development projects.

28 Dec 2019

High BMI may improve the chance of survival in certain cancers

Above average or high BMI - often linked to cancers, diabetes, cardiovascular and other diseases - may in some cases improve the chance of survival among certain cancers, new research from Flinders University indicates.

26 Dec 2019

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

Lab-grown brain organoids developed from a patient's own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it.

26 Dec 2019

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs.

23 Dec 2019

Immunologists discover new RIPK1 mechanism that leads to cell death

Scientists at St. Jude Children's Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process.

23 Dec 2019

Obesity linked to increased risk of cardiotoxicity in chemotherapy-treated patients with breast cancer

Anthracyclines remain a cornerstone of breast cancer therapy in combination with new-generation targeted drugs such as trastuzumab. Both types of drugs are major culprits in chemotherapy-induced heart disease.

23 Dec 2019

Ancestral-sequence reconstruction of FMO genes unveils structure of important enzyme

To disarm toxic substances, many organisms - including humans - possess enzymes called flavin-containing monooxygenases. Despite their importance, the structure of the enzymes has not been resolved, as the protein is too unstable to study in detail.

23 Dec 2019

Plant-rich diet protects against foodborne pathogens, mice study shows

Mice fed a plant-rich diet are less susceptible to gastrointestinal infection from a pathogen such as the one currently under investigation for a widespread E. coli outbreak tied to romaine lettuce, UT Southwestern researchers report.

23 Dec 2019

New technique provides real-time images of biomolecules in living cells

Metabolic diseases such as diabetes and obesity are ever more common globally. In addition to genetic disposition, lifestyle contributes strongly to the prevalence of these metabolic diseases.

23 Dec 2019

Immunosupressant combination therapy for glioblastoma shows promise

Researchers from the University of Texas have found an immunosuppressing target for the treatment of glioblastoma. In mice studies the team has identified CD73 macrophages which could be used to treat the cancers. The team also performed studies on human tumours to arrive at their conclusions. The study was published in the latest issue of the journal Nature Medicine this week.

23 Dec 2019

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

Biomolecules -- carbohydrates, proteins, nucleic acids, and lipids -- form the foundation of life and are responsible for carrying out every process that occurs in our bodies.

23 Dec 2019

NFCR-funded translational cancer research project receives $700,000 from Virginia Catalyst

A translational research project supported by the National Foundation for Cancer Research (NFCR) has been awarded $700,000 from Virginia Catalyst to advance its lead cancer drug candidate.

23 Dec 2019

Study finds high levels of compliance with ID rules by recreational marijuana stores in two U.S. states

A new study by collaborators at Klein Buendel, Inc. and the Prevention Research Center finds that recreational cannabis stores in Colorado and Washington state, both of which legalized adult recreational use in 2012, show high levels of compliance with rules preventing underage purchase of cannabis.

23 Dec 2019

Drugs News and Research

Study provides better understanding of mechanisms that limit cilia number in cells

Scientists discover potential drug compounds that target common type of liver cancer

Combination treatment reduces breast cancer development in mice

A new deep learning approach to predict disease-associated mutations

High BMI may improve the chance of survival in certain cancers

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

Immunologists discover new RIPK1 mechanism that leads to cell death

Obesity linked to increased risk of cardiotoxicity in chemotherapy-treated patients with breast cancer

Ancestral-sequence reconstruction of FMO genes unveils structure of important enzyme

Plant-rich diet protects against foodborne pathogens, mice study shows

New technique provides real-time images of biomolecules in living cells

Immunosupressant combination therapy for glioblastoma shows promise

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

NFCR-funded translational cancer research project receives $700,000 from Virginia Catalyst

Study finds high levels of compliance with ID rules by recreational marijuana stores in two U.S. states

Pregnant women with HIV do not always receive recommended antiretroviral medications

Behavioral intervention and risk education can improve parents' prompt disposal of leftover opioids

Electronic health records creating a ‘new era’ of health care fraud, officials say

SLU researcher honored for finding better pain treatments

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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