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Study shows CEL-2000 vaccine blocks RA progression in mice

CEL-SCI Corporation and their scientific collaborators announced today that the Company's CEL-2000 vaccine demonstrated that it is able to block the progression of rheumatoid arthritis (RA) in a mouse model.

23 Feb 2010

Robot-assisted surgery advantageous over laparoscopic surgery for uretero-pelvic junction obstruction

A comparison of two types of minimally invasive surgery to repair kidney blockages that prevent urine from draining normally to the bladder found that robot-assisted surgery was faster and resulted in less blood loss and shorter hospital stays.

22 Feb 2010

Harboring NRF2 gene may increase probability of being an endurance athlete

A few minor variations in one gene may make a difference in athletic endurance, according to a new study from Physiological Genomics.

19 Feb 2010

Contrast-enhanced MRI may help physicians differentiate between rheumatoid and psoriatic arthritis

Contrast-enhanced magnetic resonance imaging (MRI) may help physicians differentiate between rheumatoid arthritis and psoriatic arthritis in the hand and wrist enabling more targeted therapies unique to each condition, according to a study in the March issue of the American Journal of Roentgenology. Contrast-enhanced MRI uses contrast media to improve the visibility of internal bodily structures.

19 Feb 2010

Benefits of wartime camaraderie extend far beyond the battlefield: Study of U.S. Civil War veterans

Veterans who served in military units characterized by a strong esprit de corps were much less likely decades later to die of a stroke or heart condition than veterans from less cohesive companies, two UCLA economists have found.

19 Feb 2010

Study shows how genes and environmental factors influence common human diseases

A UCLA study reveals how human genes interact with their environment to boost disease risk. Published in the Feb. 18 online edition of the American Journal of Human Genetics, the findings shed light on why the search for specific gene variants linked to human diseases can only partly explain common disorders.

19 Feb 2010

FDA's proposed label changes for LABA asthma medications: GSK reviews

GlaxoSmithKline is reviewing label changes proposed today by the US Food and Drug Administration (FDA) for asthma medications containing long-acting beta-agonists (LABAs), such as GSK's Advair (salmeterol / fluticasone propionate). GSK and makers of the other affected medicines containing LABAs have 30 days to agree with the proposed changes or state why they are not warranted.

19 Feb 2010

Highly fit MS patients perform better on tests of cognitive function than less-fit patients: Study

Highly fit multiple sclerosis patients perform significantly better on tests of cognitive function than similar less-fit patients, a new study shows.

18 Feb 2010

Incyte announces 2009 financial results and key fourth-quarter accomplishments

Incyte Corporation today reported fourth quarter and full year 2009 financial results, provided an update on key fourth quarter accomplishments and 2010 objectives, and announced its 2010 financial guidance.

18 Feb 2010

Signaling protein has key role in fighting bacterial infection and inflammation in intestinal tract: Study

A signaling protein that is key in orchestrating the body's overall immune response has an important localized role in fighting bacterial infection and inflammation in the intestinal tract, according to a study by UC San Diego School of Medicine investigators, published in the journal Cell Host and Microbe.

18 Feb 2010

Viral infection can suppress immune response to secondary bacterial infection

A new study reveals how infection with the influenza virus impacts the way that the immune system responds to subsequent infections. The research, published by Cell Press in the February 18th issue of the journal Cell Host and Microbe, provides a new understanding of the physiological and pathological consequences of the flu.

18 Feb 2010

Pediatric patients face number of cardiac conditions that can impact their health

While heart disease is traditionally associated with adults, pediatric patients face a number of cardiac conditions that can impact their health.

18 Feb 2010

Taking zinc supplements reduces otitis media in healthy children: No clear evidence

A new Cochrane review did not find clear evidence that taking zinc supplements reduces the occurrence of middle ear infections or otitis media in healthy children.

18 Feb 2010

Athersys completes enrollment in phase I MultiStem allogeneic stem cell therapy clinical trial

Athersys, Inc. and Angiotech Pharmaceuticals, Inc. announced that Athersys has completed patient enrollment for its phase I clinical trial of MultiStem(R), its allogeneic stem cell therapy product, administered to individuals following acute myocardial infarction (AMI), more commonly referred to as a heart attack. Top line results of the trial are expected to be announced midyear, upon completion of the four-month patient follow-up visits and analysis of results.

17 Feb 2010

AAFA launches national PSA on "Two Main Causes of Asthma"

The Asthma and Allergy Foundation of America (AAFA) is launching a national public service announcement (PSA) supported by GlaxoSmithKline titled "Two Main Causes of Asthma." The PSA goal is to communicate an important message to the millions of Americans with asthma: that treating the two main causes of asthma symptoms may help prevent symptoms before they begin. Asthma symptoms include coughing, wheezing, difficulty breathing and chest tightness.

17 Feb 2010

Protein crucial in mediating anti-inflammatory actions of nuclear lipid receptors discovered

Researchers at the Swedish medical university Karolinska Institutet have discovered a protein that is crucial in mediating the anti-inflammatory actions of nuclear lipid receptors. The findings, published in the research journal Genes & Development, link lipid metabolism and inflammation and open up new possibilities for developing treatments of metabolic diseases associated with inflammation, such as diabetes and atherosclerosis.

17 Feb 2010

CalciMedica granted U.S. composition patent concerning key component of CRAC channel

CalciMedica today announced that the US Patent and Trademark Office has issued to CalciMedica US Patent No. 7,645,588, a composition patent involving STIM1, a key component of the calcium release-activated calcium (CRAC) channel. The patent, entitled "Composition comprising a cell comprising a STIM1 protein and an agent that modulates intracellular calcium and methods of use," has a priority date of March 4, 2003 and was issued on January 12, 2010.

17 Feb 2010

Covidien's Exalgo NDA: FDA sets new PDUFA action date

Covidien today announced that the U.S. Food and Drug Administration has set a new action date of March 1, 2010, under the Prescription Drug User Fee Act (PDUFA) for the review of the New Drug Application (NDA) for Exalgo™ (hydromorphone HCl) Extended-Release Tablets, (CII).

17 Feb 2010

Certain patients with IBD at increased risk of developing colorectal cancer: AGA's new guidelines

Certain patients with inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease of the colon, have an increased risk of developing colorectal cancer compared to individuals without IBD. A number of factors contribute to the increase in risk, which necessitates an individualized and sensible approach to surveillance in patients, according to a new medical position statement and technical review published by the American Gastroenterological Association in its official journal, Gastroenterology.

17 Feb 2010

Combination of daclizumab and interferon beta significantly reduces MS lesion formation

Biogen Idec and Facet Biotech Corporation today announced the publication of Phase 2 data showing that the addition of daclizumab to interferon beta (IFNβ) led to a significant reduction in the number of new or enlarged multiple sclerosis (MS) lesions when compared to IFNβ alone in patients with active relapsing forms of MS.

17 Feb 2010

Inflammation News and Research

Study shows CEL-2000 vaccine blocks RA progression in mice

Robot-assisted surgery advantageous over laparoscopic surgery for uretero-pelvic junction obstruction

Harboring NRF2 gene may increase probability of being an endurance athlete

Contrast-enhanced MRI may help physicians differentiate between rheumatoid and psoriatic arthritis

Benefits of wartime camaraderie extend far beyond the battlefield: Study of U.S. Civil War veterans

Study shows how genes and environmental factors influence common human diseases

FDA's proposed label changes for LABA asthma medications: GSK reviews

Highly fit MS patients perform better on tests of cognitive function than less-fit patients: Study

Incyte announces 2009 financial results and key fourth-quarter accomplishments

Signaling protein has key role in fighting bacterial infection and inflammation in intestinal tract: Study

Viral infection can suppress immune response to secondary bacterial infection

Pediatric patients face number of cardiac conditions that can impact their health

Taking zinc supplements reduces otitis media in healthy children: No clear evidence

Athersys completes enrollment in phase I MultiStem allogeneic stem cell therapy clinical trial

AAFA launches national PSA on "Two Main Causes of Asthma"

Protein crucial in mediating anti-inflammatory actions of nuclear lipid receptors discovered

CalciMedica granted U.S. composition patent concerning key component of CRAC channel

Covidien's Exalgo NDA: FDA sets new PDUFA action date

Certain patients with IBD at increased risk of developing colorectal cancer: AGA's new guidelines

Combination of daclizumab and interferon beta significantly reduces MS lesion formation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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