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SITESEEKER to be used for Otsuka’s therapeutics discovery programs

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, in disease-relevant pathways nominated by Otsuka.

From PhoreMost 21 Jan 2020

Study demonstrates striking improvements in bone marrow transplants since mid-2000s

A bone marrow transplant can be a lifesaving treatment, but it can come with life-threatening risks.

20 Jan 2020

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body's glucose balance.

20 Jan 2020

New technique accurately predicts which melanomas are likely to recur and spread

For most patients, melanoma begins with a small, pigmented spot on their skin that they notice starts to change.

20 Jan 2020

Heart failure market to experience major growth over the next 10 years, says GlobalData

The heart failure market is expected to grow from $3.7bn in 2018 to $22.1bn in 2028 across the eight major markets (8MM) at an impressive compound annual growth rate of 19.5%, according to GlobalData, a leading data and analytics company.

20 Jan 2020

Ultrasound could help reduce the use of drugs for patients with rheumatoid arthritis

A research group led by the physician Christian Dejaco is investigating circumstances under which patients may stop taking medication for rheumatoid arthritis without running the risk of the disease flaring up again.

20 Jan 2020

Refining pathological classification of breast cancer using multiplexed imaging

Breast cancer progression can vary significantly between patients. Even within the same tumor, different areas may be composed of different types of cells and characterized by different tumor structures.

20 Jan 2020

Patient enrollment in potentially life-extending clinical trials is low

Patient enrollment in clinical trials as the first course of treatment after cancer diagnosis is low, despite the fact that enrollment may increase life expectancy, according to researchers at Penn State.

20 Jan 2020

Why advanced bladder cancer still remains as deadly as it was 30 years ago?

Despite research showing that aggressive treatment with surgery, chemotherapy and radiation can extend the lives of and even cure patients with advanced bladder cancer, many don't get it.

20 Jan 2020

Virtual reality during chemotherapy could help improve breast cancer patients' quality of life

Virtual Reality during chemotherapy has been shown to improve breast cancer patients' quality of life during the most stressful treatments, according to a recent study.

20 Jan 2020

New melanoma test may better predict recurrence and improve patient care

Researchers at Brigham and Women's Hospital have developed a new technique that improves on the current method for assessing whether primary melanoma is likely to recur and spread, following surgical removal.

20 Jan 2020

Vitamin C and thiamine plus steroids do not improve septic shock outcome finds study

A randomized clinical trial showed that combining Vitamin C and thiamine with standard steroid hydrocortisone did not improve the time of survival for patients with septic shock. The study titled, “Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial,” was published in the most recent issue of JAMA.

19 Jan 2020

Psychedelics could help treat trauma-related disorders

Clinical trials suggest treatment that involves psychedelics can be more effective than psychotherapy alone.

17 Jan 2020

Study quashes the idea of using vitamin C-based cocktail for treatment of sepsis

In 2017 a paper was published asserting that intravenous vitamin C given to patients with sepsis was literally a life saver. Despite the study only looking at 47 subjects the results garnered international coverage and was adopted in many ICUs worldwide.

17 Jan 2020

Study sets the record straight on unproven therapy to treat sepsis

The Jan. 17 issue of the Journal of the American Medical Association features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert.

17 Jan 2020

Scientists urge further caution on use of Viagra for fetal therapy

University of Manchester scientists investigating a possible treatment for fetal growth restriction, a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra.

17 Jan 2020

First randomized clinical trial compares targeted therapies for acute lymphoblastic leukemia

Researchers from St. Jude Children's Research Hospital and the Chinese Children's Cancer Group led the first randomized, Phase III clinical trial comparing targeted therapies for acute lymphoblastic leukemia (ALL) driven by the Philadelphia chromosome.

17 Jan 2020

UT Southwestern study identifies new vulnerability in kidney tumors

A UT Southwestern researcher led a team that identified a new vulnerability in kidney tumors, the 10th most common cause of cancer death in men and women.

17 Jan 2020

Most youths do not get timely addiction treatment after opioid overdose

A study of more than 4 million Medicaid claims records during a recent seven-year period concludes that less than a third of the nearly 3,800 U.S. adolescents and young adults who experienced a nonfatal opioid overdose got timely (within 30 days) follow-up addiction treatment to curb or prevent future misuse and reduce the risk of a second overdose.

17 Jan 2020

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

The white blood cells are potent fighters that protect the body against foreign invaders, including pathogens and cancer cells. Scientists have found that the presence of B cells, which are powerhouses, in tumor cells, combat the disease from within.

16 Jan 2020

Therapy News and Research

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

Study demonstrates striking improvements in bone marrow transplants since mid-2000s

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

New technique accurately predicts which melanomas are likely to recur and spread

Heart failure market to experience major growth over the next 10 years, says GlobalData

Ultrasound could help reduce the use of drugs for patients with rheumatoid arthritis

Refining pathological classification of breast cancer using multiplexed imaging

Patient enrollment in potentially life-extending clinical trials is low

Why advanced bladder cancer still remains as deadly as it was 30 years ago?

Virtual reality during chemotherapy could help improve breast cancer patients' quality of life

New melanoma test may better predict recurrence and improve patient care

Vitamin C and thiamine plus steroids do not improve septic shock outcome finds study

Psychedelics could help treat trauma-related disorders

Study quashes the idea of using vitamin C-based cocktail for treatment of sepsis

Study sets the record straight on unproven therapy to treat sepsis

Scientists urge further caution on use of Viagra for fetal therapy

First randomized clinical trial compares targeted therapies for acute lymphoblastic leukemia

UT Southwestern study identifies new vulnerability in kidney tumors

Most youths do not get timely addiction treatment after opioid overdose

Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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