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Discovery of molecular origins of a heart beat

Researchers have found that molecular origins of a heart beat. They have found the proteins that make up tiny sodium channels in the tissues of the heart that can help generate the heart beats. The results of the study titled, “Structure of the Cardiac Sodium Channel” was published yesterday 19th of December 2019 in the journal Cell.

22 Dec 2019

Study finds increase in high-strength painkiller poisonings among children

The proportion of high-strength painkiller poisonings among children which result in emergency hospital admissions has increased, according to research published in the peer-reviewed journal Clinical Toxicology.

22 Dec 2019

Developing less aggressive cancer drugs that enable the immune system to recognize tumors

Doctors treat tumors mainly through surgery, radiotherapy, and chemotherapy. Over the next four years, a new project of Bielefeld University and 14 European partners will be studying targeted cancer treatments.

21 Dec 2019

Researchers study molecular elements effective in fighting malaria

The scientists research a building block of organic molecules needed for medical chemistry development. Spirocycles in nature is an element, that chemists are crazy about. This element presents in artemisinin, the most effective group of drugs against malaria.

21 Dec 2019

New 'tumor-on-a-chip' can be used to find better cancer fighting drugs

Kyoto University researchers have developed a new 'tumor-on-a-chip' device that can better mimic the environment inside the body, paving the way for improved screening of potential cancer-fighting drugs.

20 Dec 2019

Kobe scientists develop mathematical model to predict cancer drug side effects

A research team at Kobe University Hospital have further illuminated the likelihood of cancer drug side effects that can occur due to genetic mutations in the drug-metabolizing enzyme.

20 Dec 2019

p53 may play a more important role in kidney cancer than previously thought

The p53 gene, which researchers had thought was less relevant in kidney cancer, may play an important role after all – a discovery that could lead to new treatments.

20 Dec 2019

Combined datasets can expedite the discovery and development of new cancer drugs

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.

20 Dec 2019

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

p53 is the most famous cancer gene, not least because it's involved in causing over 50% of all cancers. When a cell loses its p53 gene -- when the gene becomes mutated -- it unleashes many processes that lead to the uncontrolled cell growth and refusal to die, which are hallmarks of cancer growth.

20 Dec 2019

Atomic-level structure of cardiac sodium channel

Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their function, malfunctions, disruption by many disease mutations, and response to medication.

20 Dec 2019

Proportion of powerful painkiller poisonings among children has increased, shows study

20 Dec 2019

Study: Number of e-cigarette users who began vaping at age 14 or younger has tripled

The number of e-cigarette users who began vaping at age 14 or younger has more than tripled in the last five years, say University of Michigan researchers.

20 Dec 2019

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

For the first time, scientists have discovered the molecular mechanism behind how a common virus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell & Host Microbe.

19 Dec 2019

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

For many lung cancer patients, the best treatment options involve checkpoint inhibitors. These drugs unleash a patient's immune system against their disease and can yield dramatic results, even in advanced cancers.

19 Dec 2019

Canadian First Nations communities with greater social support, trust have lower cardiac risk factors

A major study has found that Canadian First Nations communities with greater socio-economic advantages, educational opportunities, social support of family members and greater trust between community members, have lower cardiac risk factors.

19 Dec 2019

New antibody shows promise in active lupus

A new trial involving the use of an antibody called anifrolumab reports improvement in patients with systemic lupus erythematosus (SLE) after 52 weeks of treatment. The research, titled 'Trial of Anifrolumab in Active Systemic Lupus Erythematosus', is published in the New England Journal of Medicine.

19 Dec 2019

Maintenance chemotherapy after initial treatment more beneficial for metastatic colorectal cancer patients

A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenance chemotherapy after initial treatment is more beneficial for patients whose disease is under control, compared with more aggressive treatment.

19 Dec 2019

Researchers reveal the mystery in replication cycle of hepatitis D virus

A team led by Professor Patrick Labonté at the Institut National de la Recherche Scientifique in Montreal, Canada has identified the role of a key process in the replication cycle of the hepatitis D virus, an infection that is still very difficult to cure and affects 15 to 20 million people worldwide.

19 Dec 2019

New set of recommendations for clinicians to address youth vaping

In response to the pressing public health issue of vaping, clinicians of all disciplines are being asked to address this issue with youth, families and community members, despite minimal youth-focused screening or treatment guidelines.

19 Dec 2019

Severe skin and mucous membrane lesions may occur in children with bacterial pneumonia

Painful inflammatory lesions of the skin and mucous membranes may occur in children who develop bacterial pneumonia.

19 Dec 2019

Drugs News and Research

Discovery of molecular origins of a heart beat

Study finds increase in high-strength painkiller poisonings among children

Developing less aggressive cancer drugs that enable the immune system to recognize tumors

Researchers study molecular elements effective in fighting malaria

New 'tumor-on-a-chip' can be used to find better cancer fighting drugs

Kobe scientists develop mathematical model to predict cancer drug side effects

p53 may play a more important role in kidney cancer than previously thought

Combined datasets can expedite the discovery and development of new cancer drugs

Jefferson researcher probes kidney cancer's genes for interactions with p53 pathway

Atomic-level structure of cardiac sodium channel

Proportion of powerful painkiller poisonings among children has increased, shows study

Study: Number of e-cigarette users who began vaping at age 14 or younger has tripled

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

Canadian First Nations communities with greater social support, trust have lower cardiac risk factors

New antibody shows promise in active lupus

Maintenance chemotherapy after initial treatment more beneficial for metastatic colorectal cancer patients

Researchers reveal the mystery in replication cycle of hepatitis D virus

New set of recommendations for clinicians to address youth vaping

Severe skin and mucous membrane lesions may occur in children with bacterial pneumonia

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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