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Virtual PT after knee replacement provides good outcomes with lower costs

A virtual system for in-home physical therapy (PT) provides good outcomes for patients undergoing rehabilitation following total knee arthroplasty (TKA) - with lower costs than traditional in-person PT, reports a study in the January 15, 2020 issue of The Journal of Bone & Joint Surgery.

16 Jan 2020

3D structure of DNA is 'rewired' in hormone-resistant ER+ breast cancers

Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which accounts for 70% of all diagnoses.

16 Jan 2020

Study sheds light on the role of B cells in cancer immunotherapy

Cancer patients responded better to immunotherapy and had a better prognosis if their melanoma tumors contained specific clusters of B cells, according to new research from Lund University in Sweden.

16 Jan 2020

Asian parents with terminally ill children may not share psychological pain with their spouses

A study of families in Singapore with terminally ill children found that parents tend to defer discussing their psychological pain with their spouses to protect them from emotional distress.

16 Jan 2020

Study shows how extracellular vesicles help melanoma cells to spread

A new study from Finland sheds fresh light on how melanoma cells interact with other cells via extracellular vesicles they secrete.

16 Jan 2020

Harmful genetic mutations in healthy donors' stem cells may create problems in AML patients

A stem cell transplant - also called a bone marrow transplant - is a common treatment for blood cancers, such as acute myeloid leukemia.

16 Jan 2020

Blue light exposure therapy can aid in healing people with mTBI

Early morning blue light exposure therapy can aid the healing process of people impact by mild traumatic brain injury, according to new research from the University of Arizona.

16 Jan 2020

B cell count tells how certain cancers will respond to immunotherapy

Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the body’s known capability to mount an immune response against the foreign antigen-bearing tumor cells.

15 Jan 2020

Blood vessels in women age quicker than men's

A new study shows that blood vessels, including large and small arteries, in women, age much faster in women than in men. This is the first time this finding has been reported. The study, published in the journal JAMA Cardiology in January 2020, will be helpful in showing how women are at a different risk for cardiovascular disease, both with respect to the type and the timing, than men.

15 Jan 2020

Immune system contribution to tumor heterogeneity may influence liver cancer growth

Researchers at Mount Sinai School of Medicine say the immune system might contribute to the tumor heterogeneity seen in liver cancer that can affect the rate of cancer growth.

15 Jan 2020

Number of operations performed in a hospital linked to success of cancer surgery

Tumors of the colon, so-called colorectal carcinomas, are the second to third most frequent tumors in women and men in Germany. The surgical removal of the tumors is a central component of the therapy.

14 Jan 2020

Targeted transcranial electrical stimulation can improve metamemories

HRL Laboratories, LLC, researchers have published results showing that targeted transcranial electrical stimulation during slow-wave sleep can improve metamemories of specific episodes by nearly 20% after only one viewing of the episode, compared to controls. Metamemory describes the sensitivity of whether memories are recalled accurately or not, such as during eyewitness testimony.

14 Jan 2020

Overactivation of neuroimmune gene leads to schizophrenia-like changes in mice

Excessive activity of an immune system gene previously linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study publishing on January 14 in the open-access journal PLOS Biology by Ashley Comer and Alberto Cruz-Martín of Boston University and colleagues.

14 Jan 2020

KU Leuven researchers develop new antibacterial strategy that weakens bacteria

Bioscience engineers from KU Leuven in Belgium have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. Unlike with antibiotics, there is no resistance to this strategy, because the non-resistant bacteria outnumber resistant ones.

14 Jan 2020

Study reveals how clotting protein and blood platelets promote immune evasion, tumor progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer.

14 Jan 2020

Biomaterial-based vaccine has potential to completely eliminate AML cells

Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML treatment for over 40 years, and while it often causes the cancer to go into remission, it rarely completely eliminates the cancerous cells, which then lead to disease recurrence in nearly half of treated patients.

14 Jan 2020

Study shows how treatment resistance develops in patients with bile duct cancer

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute shows how resistance to a promising targeted drug develops in patients with a rare, lethal cancer of the bile ducts called cholangiocarcinoma.

14 Jan 2020