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Scientists modify approved cancer drug to develop new antibiotic

Antibiotic-resistant bacteria are increasingly the source of deadly infections. A team of scientists from the Technical University of Munich and the Helmholtz Center for Infection Research in Braunschweig have now modified an approved cancer drug to develop an active agent against multidrug-resistant pathogens.

16 Dec 2019

Novel and targeted cellular product causes cell death in non-Hodgkin lymphoma models

Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are sensitive or resistant to standard therapies.

16 Dec 2019

Modifying a cancer drug has created a new agent for multi-resistant infections

Researchers have modified a cancer drug to create an agent that is effective at treating multi-drug-resistant infections.

16 Dec 2019

Important discovery about male infertility could lead to new treatments

Using a new mouse model, Penn Medicine researchers have identified defects in the sperm epigenome that cause male infertility.

16 Dec 2019

Promising greater safety, a tiny widget creates chaos for tube feeders

Rachel Glenn loves to puree food and put it in her 4-year-old's feeding tube. The Arkansas mom said her thick concoctions of fruit, vegetables, meat and grains provide the concentrated nutrition he needs.

16 Dec 2019

What would happen if the ACA went away?

Any day now, the 5th Circuit Court of Appeals in New Orleans could rule the entire Affordable Care Act unconstitutional.

16 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Study shows non-TB lung infections rising; more in women and older people

Each year, more and more people are getting mycobacterial lung infections, and the total number living with such diseases is going up, according to a new study published in the journal Annals of the American Thoracic Society. Those at greatest risk are people above the age of 65 years and the elderly.

15 Dec 2019

Integrated approach needs to be used to address opioid use among psychiatric patients

Opioid use among psychiatric hospital patients needs to be addressed through an integrated approach to managing mental illness, pain and substance use, a study by researchers at the University of Waterloo has found.

14 Dec 2019

Novel drug shows efficacy against advanced ROS1 and NTRK fusion-positive NSCLC

Pooled analysis of three phase 1 and 2 clinical trials published online ahead of print in the journal Lancet Oncology show that the drug entrectinib is effective and well-tolerated against advanced ROS1 and NTRK fusion-positive non-small cell lung cancers (NSCLC).

14 Dec 2019

Community-based program enables donation of tumor tissue and blood samples for research

Precision medicine with targeted therapies has led to improved treatment options and patient outcomes. These approaches were developed by studying tumors grown in laboratories and patient samples obtained before and during their treatment.

14 Dec 2019

Problem drinkers have higher likelihood of using benzodiazepines

Problem drinkers are more likely than teetotalers and moderate drinkers to take benzodiazepines, a class of sedatives that are among the most commonly prescribed drugs -- and the most abused.

14 Dec 2019

Neuroscientists develop new method for uniquely targeted gene therapy

Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of years to weeks.

13 Dec 2019

Finding non-invasive nuclear medicine technique to predict effectiveness of therapy for tumors

Researchers have taken a critical step toward developing a non-invasive nuclear medicine technique that can predict the effectiveness of therapy for cancerous tumors, allowing for personalized, precision treatment.

13 Dec 2019

Patient-reported outcomes linked to aromatase inhibitor adherence

If you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients commonly answer in cancer clinical trials, according to research findings to be presented Friday, Dec. 13 at the San Antonio Breast Cancer Symposium.

13 Dec 2019

In the fight for money for the opioid crisis, will the youngest victims be left out?

Babies born to mothers who used opioids during pregnancy represent one of the most distressing legacies of an opioid epidemic that has claimed almost 400,000 lives and ravaged communities.

13 Dec 2019

Human genetics evidence predictive of drug development success, study shows

A new drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease; a finding that can help pharmaceutical companies to focus their drug development efforts.

From PLOS ONE 13 Dec 2019

House drug pricing bill to reduce costs, improve access to life-saving therapies

H.R. 3, the Elijah E. Cummings Lower Drug Costs Now Act passed by the House of Representatives today introduces critically needed and significant steps to reduce costs and improve access to life-saving therapies for conditions including HIV and hepatitis C.

13 Dec 2019

Introduction of drug amnesty bins is a good step towards minimizing harm at music festivals

The NSW Government’s introduction of amnesty bins at music festivals has been welcomed by Alex Greenwich, Member for Sydney, as an important first step in keeping people safe.

13 Dec 2019

Influenza research could pave way for new and improved drugs, vaccines

Researchers at the Centenary Institute and the University of Sydney have discovered a key reason as to why the influenza virus is so effective at establishing infection and causing damage in the lungs.

13 Dec 2019