Infectious Diseases News and Research

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Powdered form of anthrax vaccine could eliminate needle injections

Researchers have developed a powdered form of an anthrax vaccine that could potentially be inhaled through the nose and eliminate the need for needle injections.

26 Aug 2004

Mouse stem cells may help restore hearing loss in humans

The work is important because, in humans, inner ear sensory hair cells are a precious commodity. Humans are born with only about sixteen thousand of these sound detectors in each ear, which can be easily damaged by age, certain illnesses, exposure to loud sounds, and some medications. Once damaged, the cells do not easily grow back. And with the cell loss comes so-called irreversible hearing loss.

26 Aug 2004

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Human Genome Sciences has begun dosing patients in a Phase 1 clinical trial of HGS-TR2J, a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

25 Aug 2004

Regular exercise boosts immune system in older men

As it turns out, judging by the reaction strength of their immune system to an unknown, but harmless, protein antigen, it’s possible for men over 70 to mount an immune response similar to that produced by much younger men -- if they get regular moderate physical activity of about six hours a week.

25 Aug 2004

Clinicians have been able to reduce mortality rates in HIV positive children from 15 to 3 percent

"This is perhaps the first time that it has been demonstrated that HIV positive children can be successfully treated with antiretroviral therapy in resource-limited settings and the outcomes are comparable to those we have seen in U.S. pediatric antiretroviral clinical trials,"

23 Aug 2004

Diarrhea the leading cause of death among the developing world's children

To most people in the developed world, diarrhea is a nuisance. It means some discomfort and maybe a trip to the local pharmacy.

23 Aug 2004

Peginterferon and Ribavirin combination promising for those with HIV and HCV

Since the introduction of highly active combination drug therapy for HIV, liver failure attributable to infection with the hepatitis C virus (HCV) has become a leading cause of death among those infected with the virus that causes AIDS.

22 Aug 2004

Development of plant-derived topical medications to prevent HIV/AIDS and other STD's

Researchers at the Biodesign Institute at ASU have been tapped to lead development of plant-derived topical medications that would prevent HIV/AIDS and other sexually-transmitted diseases.

21 Aug 2004

Antibodies produced by shark immune systems could be used to detect human pathogens

A recent discovery shows that antibodies produced by shark immune systems could be used to detect a range of human pathogens some of which have the potential to be used as biological warfare agents.

20 Aug 2004

2004 AIDS Vaccine Conference has announced it's forthcoming programme

The Conference will examine the entire spectrum of issues in AIDS vaccine development and deployment, including the global effort in preventative and therapeutic vaccines, immunology, pediatric and adolescent vaccines, clinical trials in emerging countries and the need for strong political and financial commitment.

17 Aug 2004

Large-scale computer simulations help understand SARS

A Mayo Clinic researcher is the first to develop a series of three-dimensional (3D) models of an enzyme responsible for the replication of the deadly SARS (Severe Acute Respiratory syndrome) virus.

17 Aug 2004

Contract for the production of an investigational vaccine based on an H9N2 strain of avian influenza virus

In 1999 and 2003, an H9N2 influenza strain caused illness in three people in Hong Kong. Scientists are concerned about H9N2 and other emerging types of avian influenza viruses because as they spread—most commonly through poultry—they continually mutate, increasing chances that they may infect humans, evade the body’s immune response and become more lethal.

17 Aug 2004

Study on RNAi technology targeting neurodegenerative diseases

Sirna Therapeutics has announced the publication of preclinical studies evaluating RNA interference-based therapies for a class of inherited neurodegenerative diseases of the central nervous system (CNS) in the current issue of Nature Medicine.

16 Aug 2004

Children vaccinated against chickenpox who then contract chickenpox are half as contagious as those who have not been vaccinated

A study published in the current issue of the Journal of the American Medical Association shows that children and young adults who have had the chickenpox vaccine and gone on to contract chickenpox are half as contagious as those who have not been vaccinated.

11 Aug 2004

Significant number of pediatric physicians fail to diagnose Kawasaki disease

Researchers at the University of California, San Diego School of Medicine report in the August 10 issue of Pediatric Infectious Disease Journal that a significant number of pediatric physicians fail to diagnose Kawasaki disease in children younger than six months and older than eight years.

11 Aug 2004

Susceptibility to vCJD was predicted to increase during childhood, peak during adolescence and decrease sharply afterwards

That young people tend to eat more beef products is not enough to explain the strikingly high proportion of new-variant Creutzfeldt-Jacob disease cases among children and adolescents. An article published this week in BMC Infectious Diseases, shows that young people must also be more susceptible to vCJD infection because of their age.

9 Aug 2004

Automated science speeds solution of Human Genome data

Scientists in Argonne's Biosciences Division are automating and accelerating the complex processes that coax a protein to reveal its structure so they can learn the role Nature assigned it.

6 Aug 2004

Self-recovery from Hep C infection linked to genes that suppress action of killer immune cells

In a study to be published in Science online Aug. 6, researchers at Johns Hopkins have found that genes involved in suppressing the body's defensive "killer" immune cells are a potential key factor in spontaneous recovery from hepatitis C.

5 Aug 2004

Potential of genomics in disease research yet to be realized

Over the past decade genomics has revolutionized our understanding of how microorganisms cause disease. However, genomic studies need to be extended to a more diverse array of microorganisms and research tools improved to gain additional insights into pathogenesis, according to a new report released by the American Academy of Microbiology.

5 Aug 2004

Experimental vaccine against ricin

Scientists have developed an experimental vaccine against ricin, a potential biological threat agent, which fully protected mice from aerosol challenge with lethal doses of the toxin.

5 Aug 2004

Infectious Diseases News and Research

Powdered form of anthrax vaccine could eliminate needle injections

Mouse stem cells may help restore hearing loss in humans

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Regular exercise boosts immune system in older men

Clinicians have been able to reduce mortality rates in HIV positive children from 15 to 3 percent

Diarrhea the leading cause of death among the developing world's children

Peginterferon and Ribavirin combination promising for those with HIV and HCV

Development of plant-derived topical medications to prevent HIV/AIDS and other STD's

Antibodies produced by shark immune systems could be used to detect human pathogens

2004 AIDS Vaccine Conference has announced it's forthcoming programme

Large-scale computer simulations help understand SARS

Contract for the production of an investigational vaccine based on an H9N2 strain of avian influenza virus

Study on RNAi technology targeting neurodegenerative diseases

Children vaccinated against chickenpox who then contract chickenpox are half as contagious as those who have not been vaccinated

Significant number of pediatric physicians fail to diagnose Kawasaki disease

Susceptibility to vCJD was predicted to increase during childhood, peak during adolescence and decrease sharply afterwards

Automated science speeds solution of Human Genome data

Self-recovery from Hep C infection linked to genes that suppress action of killer immune cells

Potential of genomics in disease research yet to be realized

Experimental vaccine against ricin

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