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Enzyme implicated in telomere repair offers new avenues for cancer therapy

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.

7 May 2024

Study finds unjustified antibiotic administration in Swedish newborns

Newborns in Sweden are given antibiotics for suspected sepsis to an unjustified extent. This is according to a study by the University of Gothenburg in over one million newborns.

7 May 2024

Purdue researcher receives $2.4 million NIH grant to combat antimicrobial resistance in lung infections

Qi "Tony" Zhou, a researcher in Purdue University's College of Pharmacy has received a $2.4 million grant from the National Institutes of Health to fight lung infections that have established a resistance to antimicrobial drugs.

6 May 2024

Raw meat-based diet for pets linked to drug-resistant bacteria, prompting concerns over public health risks

Study reveals that raw meat-based pet diets (RMBDs) often harbor multidrug-resistant bacteria, posing significant health risks to both pets and humans, unlike conventionally processed pet foods.

5 May 2024

Key transport systems fuel rapid E. coli growth in UTIs

Through a quirk of anatomy, women are especially prone to urinary tract infections, with almost half dealing with one at some point in their lives.

3 May 2024

Researchers highlight critical need for more effective treatments for women with bacterial vaginosis

Bacterial Vaginosis (BV) affects about one-quarter of reproductive-age women and is linked to adverse health outcomes, such as increased HIV risk.

2 May 2024

Columbia researchers uncover brain's ability to control inflammation

The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.

2 May 2024

Gut microbiome study challenges established cancer biomarkers, identifies new bacterial links to colorectal cancer

Study identified that several specific bacterial species were significantly associated with colorectal cancer, challenging previous assumptions about established biomarkers once adjusted for important covariates.

1 May 2024

New approach to inhibit strep’s DNA-cleaving enzymes

An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule.

30 Apr 2024

Age and sex impact antimicrobial resistance levels, research shows

New research presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona 27-30 April) shows that levels of resistance to antimicrobials (AMR) varies with age and sex, with age in particular showing substantial variation both between and within countries.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Targeting skin microbiome rivals: Unveiling epilancin A37's antimicrobial mechanism

Many bacteria produce substances to gain an advantage over competitors in their highly competitive natural environment.

29 Apr 2024

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

A low-fiber “Western diet” causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection.

29 Apr 2024

Study reveals high levels of antibiotic resistance in meat sold for consumption

New research presented at the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) has found substantial levels of resistance to critically important antibiotics in meat sold for human and animal consumption.

28 Apr 2024

Expert warns of the continuous dangers posed by polio and other enteroviruses

Consistently high vaccination rates and global health surveillance programs have helped eliminate poliomyelitis (polio) in almost all countries of the world, except Afghanistan and Pakistan.

28 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Leveraging CRISPR/Cas technology to address antimicrobial resistance

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will give an overview of the molecular biology of CRISPR technology in explaining how it can used to tackle antimicrobial resistance.

26 Apr 2024

Ohio State study reveals bacterial defense mechanism against phages

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

26 Apr 2024

WHO and Government of France host high-level meeting to combat meningitis

Global leaders highlight the need to defeat meningitis – a leading cause of disability – at a high-level meeting co-hosted by the World Health Organization and Government of France, under the High Patronage of Emmanuel Macron, President of the French Republic.

26 Apr 2024

WHO data reveals extensive antibiotic overuse during COVID-19 pandemic

New evidence from the World Health Organization shows the extensive overuse of antibiotics during COVID-19 pandemic worldwide, which may have exacerbated "silent" spread of antimicrobial resistance (AMR).

26 Apr 2024

Bacterial News and Research

Enzyme implicated in telomere repair offers new avenues for cancer therapy

Study finds unjustified antibiotic administration in Swedish newborns

Purdue researcher receives $2.4 million NIH grant to combat antimicrobial resistance in lung infections

Raw meat-based diet for pets linked to drug-resistant bacteria, prompting concerns over public health risks

Key transport systems fuel rapid E. coli growth in UTIs

Researchers highlight critical need for more effective treatments for women with bacterial vaginosis

Columbia researchers uncover brain's ability to control inflammation

Gut microbiome study challenges established cancer biomarkers, identifies new bacterial links to colorectal cancer

New approach to inhibit strep’s DNA-cleaving enzymes

Age and sex impact antimicrobial resistance levels, research shows

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Targeting skin microbiome rivals: Unveiling epilancin A37's antimicrobial mechanism

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

Study reveals high levels of antibiotic resistance in meat sold for consumption

Expert warns of the continuous dangers posed by polio and other enteroviruses

Harnessing immune enhancement to combat drug-resistant tuberculosis

Leveraging CRISPR/Cas technology to address antimicrobial resistance

Ohio State study reveals bacterial defense mechanism against phages

WHO and Government of France host high-level meeting to combat meningitis

WHO data reveals extensive antibiotic overuse during COVID-19 pandemic

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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