Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

New gene therapy cures babies with fatal 'Bubble Boy' disease

A new gene therapy created by US researchers appears to have cured eight infant boys born with a rare genetic disorder referred to as “Bubble Boy” disease.

18 Apr 2019

Online atlas created to identify, classify protein signatures present at AML diagnosis

Only about one in four people diagnosed with acute myelogenous leukemia (AML) survive five years after the initial diagnosis.

17 Apr 2019

Research sheds light on how leukemia cells become resistant to drugs

Three children Alejandro Gutierrez, MD, treated for leukemia during his fellowship at Boston Children's Hospital still haunt him more than a decade later.

17 Apr 2019

CRISPR-scanning could lead to more effective treatments for cancer

11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to prevent blood cells from replicating again and again and again, growing tumors.

16 Apr 2019

Stem cells from patient's own bone marrow holds great potential for osteoarthritis

Stem cells collected from the patient's own bone marrow holds great interest as a potential therapy for osteoarthritis of the knee because of their ability to regenerate the damaged cartilage.

15 Apr 2019

Researchers map genetic mutation behind incurable disease

Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis.

10 Apr 2019

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

On a normal day, the cells of a human liver do what they do best - making key blood proteins, clearing toxins from the blood and sending their remains down the digestive tract in a never-ending stream of bile.

9 Apr 2019

Scientists visualize immune cells fighting blood cancer for the first time

When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease.

8 Apr 2019

New clinical trials to investigate combination immunotherapy for treating advanced cancers

City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly-impossible-to-treat cancer into a disease that can be corralled into remission.

8 Apr 2019

Study compares use of breast milk to formula in children who underwent bone marrow transplant

A new pilot study compared the use of human breast milk to formula in children less than 5 years of age who underwent bone marrow transplant (BMT), measuring the levels of inflammatory and pro-inflammatory biomarkers in the stool and blood to assess inflammatory injury to the intestinal microbiome.

5 Apr 2019

Transplantation of bone marrow-derived EPCs slows ALS disease progression

Transplantation of human bone marrow-derived endothelial progenitor cells into mice mimicking symptoms of amyotrophic lateral sclerosis (ALS) helped mor, University of South Florida researchers report.

3 Apr 2019

Scientists have more evidence of why clear margins in breast cancer surgery are such good news

When a breast cancer tumor is removed with no signs of cancer left behind, it's great news for patients, and now scientists have more evidence of why.

1 Apr 2019

Research reveals genomic basis of acute erythroid leukemia

Acute erythroid leukemia is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.

30 Mar 2019

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

The U.S. Food and Drug Administration today approved Mavenclad (cladribine) tablets to treat relapsing forms of multiple sclerosis (MS) in adults, to include relapsing-remitting disease and active secondary progressive disease.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

People born with short telomeres found to have short-lived immune system cells

Scientists at Johns Hopkins say they have found that people born with abnormally short chromosome endcaps, or telomeres, have immune system cells that age and die prematurely.

27 Mar 2019

Modulating stiffness of blood-forming stem cells could facilitate mobilization procedures

Scientists at Winship Cancer Institute of Emory University, Children's Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells' stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants.

25 Mar 2019

Bone Marrow News and Research

Further Reading

New gene therapy cures babies with fatal 'Bubble Boy' disease

Online atlas created to identify, classify protein signatures present at AML diagnosis

Research sheds light on how leukemia cells become resistant to drugs

CRISPR-scanning could lead to more effective treatments for cancer

Stem cells from patient's own bone marrow holds great potential for osteoarthritis

Researchers map genetic mutation behind incurable disease

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

Scientists visualize immune cells fighting blood cancer for the first time

New clinical trials to investigate combination immunotherapy for treating advanced cancers

Study compares use of breast milk to formula in children who underwent bone marrow transplant

Transplantation of bone marrow-derived EPCs slows ALS disease progression

Scientists have more evidence of why clear margins in breast cancer surgery are such good news

Research reveals genomic basis of acute erythroid leukemia

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

People born with short telomeres found to have short-lived immune system cells

Modulating stiffness of blood-forming stem cells could facilitate mobilization procedures

Surprising discovery offers clues to limit graft-vs.-host disease

Study provides new insight into blood cell and immune cell production

Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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