Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Novel 3D cancer model to accelerate development of new and better treatments

A scientist at the University of Virginia School of Medicine, working with local biotech company HemoShear Therapeutics, has created a three-dimensional model of a cancer tumor that he says has the potential to replicate the complex nature and behavior of a real tumor.

7 May 2018

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer treatment decisions, today announced the presentation of data supporting clinical use of the DecisionDx®-Melanoma test to inform sentinel lymph node biopsy (SLNB) recommendations.

7 May 2018

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Due to the opioid epidemic, hepatitis C virus is increasing among pregnant women, resulting in a greater risk of perinatal transmission and HCV infection among children.

2 May 2018

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

Ibuprofen, aspirin, and other non-steroidal anti-inflammatory medications are among the most commonly utilized medications in the United States. Primarily for treating pain, inflammation, and preventing cardiovascular disease, NSAIDs' promising anti-cancer properties have been highlighted by a growing body of data in recent years.

2 May 2018

Study highlights impact of early detection on skin cancer survival

Skin cancer survivors know firsthand that the disease is most treatable when detected early, so they're more likely to be vigilant about skin exams —and new research shows that such vigilance pays off.

26 Apr 2018

Studies provide advanced knowledge about renal cancer

Cell, the most prestigious international journal in the field of biology, is today publishing a set of three papers on renal cancer. Among the authors of these papers is Dr José Ignacio López, head of the Pathological Anatomy Service of University Hospital Cruces and tenured lecturer in Pathological Anatomy at the UPV/EHU's Faculty of Medicine and Nursing.

24 Apr 2018

Roswell Park researchers identify driver of cancer-promoting metabolic changes

Roswell Park Comprehensive Cancer Center researchers have identified a potential key player promoting cancer progression through changes in the cell environment that are conducive to metastasis.

17 Apr 2018

Axillary ultrasound imaging found to be inferior for detecting lymph node metastases in breast cancer

For patients diagnosed with breast cancer, determining whether cancer cells have spread to the axillary lymph nodes of the armpit is important for guiding treatment decisions. It has been debated whether axillary ultrasound imaging is equally sensitive for detecting axillary metastatic lymph nodes in different subtypes of breast cancer.

17 Apr 2018

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress™ 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list in the USA were more than 50% less likely to receive a transplant in 2014-2016 than they were in 2005-2007.

13 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples.

12 Apr 2018

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung.

12 Apr 2018

High carbohydrate and sugar linked to disease recurrence, death in head and neck cancer patients

Consuming high amounts of carbohydrates and various forms of sugar during the year prior to treatment for head and neck cancer may increase patients' risks of cancer recurrence and mortality, a new study reports.

12 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Study finds link between industry payments and prescription practices for two cancer types

Physicians who received payment from pharmaceutical companies for meals, talks and travel were more likely to prescribe those companies' drugs for two cancer types, a University of North Carolina Lineberger Comprehensive Cancer Center-led study has found.

9 Apr 2018

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth of cells in liver cancer.

29 Mar 2018

Alcohol-related liver cancer may have poor prognosis than other types

A new study indicates that patients with alcohol-related liver cancer often do not live as long as patients with liver cancer that is not associated with alcohol consumption, mainly due to diagnoses at later stages.

28 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

Carcinoma News and Research

Further Reading

Novel 3D cancer model to accelerate development of new and better treatments

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

Study highlights impact of early detection on skin cancer survival

Studies provide advanced knowledge about renal cancer

Roswell Park researchers identify driver of cancer-promoting metabolic changes

Axillary ultrasound imaging found to be inferior for detecting lymph node metastases in breast cancer

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Research reveals immune suppressive role of soluble antibodies in tumor progression

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

High carbohydrate and sugar linked to disease recurrence, death in head and neck cancer patients

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Study finds link between industry payments and prescription practices for two cancer types

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Alcohol-related liver cancer may have poor prognosis than other types

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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