Intensive Care News and Research

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Characteristics and outcomes in patients hospitalized with COVID-19 in South Africa

A new research letter assessed patients hospitalized with a positive SARS-CoV-2 test during the fourth wave compared to the previous waves.

4 Jan 2022

CDC report shows COVID vaccines safe for children, serious side effects rare

Researchers determine the characteristics and clinical outcomes of COVID-19 in children and adolescents 18 years or younger.

3 Jan 2022

Altered cytokine profiles of COVID-19-infected mother-infant dyads may impair long-term infant health

New study findings suggest that both SARS-CoV-2-infected mothers and their fetuses have increased levels of inflammatory cytokines throughout gestation, which may potentially impact fetus health in the long term.

31 Dec 2021

SARS-CoV-2 omicron variant may be less severe than the delta variant

A new study reveals that omicron infections in South Africa are associated with lower rates of hospital admissions and lower disease severity compared to beta and delta infections.

31 Dec 2021

Pre-existing immunity against influenza can lower SARS-CoV-2 infection burden and spread

A recent study by a team of European researchers demonstrated how antibodies induced by currently circulating influenza A H1N1 strains can cross-react with the important part of the SARS-CoV-2 spike glycoprotein that interacts with the human cell receptor. Their paper is currently available on the medRxiv* preprint server while it undergoes peer review.

28 Dec 2021

SARS-CoV-2-induced kidney damage

Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infects the kidneys and contributes to tissue scarring, as shown by researchers from the RWTH Uniklinik Aachen, Germany, and Radboudumc, The Netherlands. The developed scar tissue in the infected kidneys may suggest a possible impact on kidney outcomes in the long term.

27 Dec 2021

APOE4 allele gene linked to increased risk of severe COVID-19

A study conducted at the University of Helsinki and the Helsinki University Hospital suggests that the APOE4 allele may also increase cerebral microhemorrhages related to COVID-19 and associate with mental fatigue related to long COVID.

27 Dec 2021

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Infection-fighting B cells retain better memory of the coronavirus spike protein in University Hospital patients who recover from less-severe cases of COVID-19 than in those recovering from severe COVID-19, a new study suggests.

24 Dec 2021

Coinfection of SARS-CoV-2 and human rhinovirus associated with more severe health outcomes

Researchers discuss the incidence and effect of coinfections with SARS-CoV-2 and human rhinovirus.

23 Dec 2021

Study reports that children develop sustained cross-reactive adaptive immunity against coronaviruses

A new study shows that both antibody and cellular arms of the adaptive immune response against SARS-CoV-2 are displayed strong, sustained, and cross-reactive against other coronaviruses, in young children than the immune responses in adults.

23 Dec 2021

More breakthrough infections but less severe COVID-19 with Omicron

In a recent study posted to the bioRxiv* pre-print server, an international team of researchers reported the occurrence of coronavirus disease 2019 (COVID-19) breakthrough infections (BTIs) among health care workers (HCWs) participating in a phase III vaccine trial in Sisonke, South Africa.

22 Dec 2021

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

New parents slapped with surprise bills for treating newborns

After Christine Malik gave birth to her first daughter three years ago, a clinician affiliated with a company called Pediatrix entered the hospital room and fitted the infant with sensors and wires for a hearing test.

22 Dec 2021

As pandemic wears down hospital staff, one town offers groceries to say thanks

This mountain community — which comes alive during the winter ski season and annual Sundance Film Festival — is home to the Park City Hospital, which has 460 employees.

22 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Risk of hospitalization for infants and children with COVID-19 below 1%

Children are a low-risk group for COVID-19 following infection with SARS-CoV-2, with less than 2% of European hospitalizations with the disease being in children below the age of 19.

21 Dec 2021

Pandemic poses short- and long-term risks to babies, especially boys

The pandemic has created a hostile environment for pregnant people and their babies. Stress levels among expectant mothers have soared. Pregnant women with covid are five times as likely as uninfected pregnant people to require intensive care and 22 times as likely to die. Infected moms are four times as likely to have a stillborn child.

21 Dec 2021

Impact of acute kidney injury associated gene expression in human kidney cells

A new study attempts to perform a comparative single-cell census of human kidneys employing samples from individuals suffering from acute kidney injury and controls without the condition.

20 Dec 2021

Study: Middle-aged men are more likely to die after surgery than women

Middle-aged men are around 50% more likely to die after surgery than middle-aged women, according to new research being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care (ESAIC), held online this year.

20 Dec 2021

Women experienced greater pain severity than men during COVID-19 lockdowns

COVID-19 lockdown measures appear to have had drastically different effects on men and women living with chronic pain, with women experiencing greater pain severity, according to new research being presented at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care, held online this year.

20 Dec 2021