Pharmaceuticals News and Research

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New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes.

5 Mar 2021

Experimental safety switch reduces severity of CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

4 Mar 2021

KHN’s ‘What the Health?’: Good and not-so-good news on Covid

There's good news and bad news on Covid-19 this week. On the one hand, several million doses of the one-shot Johnson & Johnson vaccine authorized by the FDA for emergency use are already going into the arms of people around the nation.

4 Mar 2021

Accidentally trashed, thawed or expired: reports of Covid vaccine spoilage

As the speed of covid vaccinations picks up, so do the reports of doses going to waste. And it’s more than just a handful at the end of the day because of a few appointment cancellations. Health officials are trying to rein in waste without slowing down vaccinations.

4 Mar 2021

New substance suppresses the growth of harmful bacteria that cause periodontitis

Targeted, efficient and with few side effects: A new method for combating periodontitis could render the use of broad-spectrum antibiotics superfluous.

3 Mar 2021

Scientists reprogram a common bacterium to make designer sugar-based drug

Envisioning an animal-free drug supply, scientists have - for the first time - reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

2 Mar 2021

New technique uncovers the tricks used by cancer cells to evade immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

1 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

Scientists develop a simple method to make drug precursor

Save your silver! It's better used for jewelry than as a catalyst for drugs. Rice University scientists have developed a greatly simplified method to make fluoroketones, precursors for drug design and manufacture that typically require a silver catalyst.

27 Feb 2021

Critical Path Institute and global partners establish Ataxia Consortium

Critical Path Institute (C-Path) today announced the launch of the Critical Path to Therapeutics for the Ataxias (CPTA) Consortium, a public-private partnership focused on optimizing clinical trials for inherited ataxias.

27 Feb 2021

Researchers develop an electroceutical for preterm labor detection and treatment

Preterm labor comprises 12.7% of all pregnancies. Although the overall rate of pregnancy is decreasing, the occurrence of premature birth due to preterm labor in south korea has been increasing over the past 7 years.

26 Feb 2021

Nanobowls show potential for diagnostics and treatment of Alzheimer's

Scientists are still a long way from being able to treat Alzheimer's Disease, in part because the protein aggregates that can become brain plaques, a hallmark of the disease, are hard to study.

26 Feb 2021

Why Astrazeneca and J&J’s vaccines, in use the world over, are still on hold in America

The World Health Organization greenlighted emergency use of AstraZeneca and Oxford's covid-19 vaccine this month, following in the steps of the United Kingdom, the European Union and others, who are already injecting it as quickly as possible into the masses.

26 Feb 2021

New device accelerates transdermal penetration of drug molecules and extraction of interstitial fluid

A pain-free, organic and biodegradable drug delivery patch may be on the horizon for home health care patients soon.

26 Feb 2021

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.

25 Feb 2021

SARS-CoV-2 does not infect the entire body in the same way, finds study

COVID-19, the disease caused by the pandemic coronavirus SARS-CoV-2, is primarily regarded as a respiratory infection. Yet the virus has also become known for affecting other parts of the body in ways not as well understood, sometimes with longer-term consequences, such as heart arrhythmia, fatigue and "brain fog."

24 Feb 2021

New microneedle patches for delivery of psychedelic pharmaceuticals

Although one may think of psychedelic pharmaceuticals as being dangerous and detrimental, scientists have been conducting experiments and clinical trials on some of them and have obtained positive results when testing them for medical use.

23 Feb 2021

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

The U.S. government has invested billions of dollars in manufacturing, used a wartime act dozens of times to boost supplies and yet there's still not enough covid vaccine on the way to meet demand — or even the government's own goals for national immunization.

23 Feb 2021

mRNA Therapeutics – Analytical and Bioanalytical Characterization

NewsMed interviews Anette Bak from AstraZeneca about her research on developments in mRNA therapeutics that she will present at Pittcon 2021.

From Pittcon 23 Feb 2021

Current monoclonal antibodies less potent against SARS-CoV-2 variants

Researchers at the New York University Grossman School of Medicine and Biohaven Pharmaceuticals found that the REGN10933 and REGN10987 combination was 9.1-fold less potent on the B.1.351 variant, which emerged in South Africa, and 16.2-fold less potent on mink cluster 5.

22 Feb 2021

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Pharmaceuticals News and Research

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Experimental safety switch reduces severity of CAR-T immunotherapy-related side effects

KHN’s ‘What the Health?’: Good and not-so-good news on Covid

Accidentally trashed, thawed or expired: reports of Covid vaccine spoilage

New substance suppresses the growth of harmful bacteria that cause periodontitis

Scientists reprogram a common bacterium to make designer sugar-based drug

New technique uncovers the tricks used by cancer cells to evade immunotherapies

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

Scientists develop a simple method to make drug precursor

Critical Path Institute and global partners establish Ataxia Consortium

Researchers develop an electroceutical for preterm labor detection and treatment

Nanobowls show potential for diagnostics and treatment of Alzheimer's

Why Astrazeneca and J&J’s vaccines, in use the world over, are still on hold in America

New device accelerates transdermal penetration of drug molecules and extraction of interstitial fluid

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

SARS-CoV-2 does not infect the entire body in the same way, finds study

New microneedle patches for delivery of psychedelic pharmaceuticals

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

mRNA Therapeutics – Analytical and Bioanalytical Characterization

Current monoclonal antibodies less potent against SARS-CoV-2 variants

Oxygen Measurement eBook - Easily Understand Dissolved Oxygen Measurement eBook

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Bringing real-time analytics to downstream bioprocess monitoring