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FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

The U.S. Food and Drug Administration (FDA) has granted accelerated approval for the immunotherapy afamitresgene autoleuecel (Tecelra®, also known as afami-cel) for the treatment of adults with a rare soft tissue cancer called synovial sarcoma.

2 Aug 2024

Olympic athletes overcome health challenges to reach the pinnacle of their sport

The athletes have done the training and achieved their dreams, a trip to the Paris Olympics set to begin Friday July 26th.

2 Aug 2024

Trust in US physicians and hospitals plummeted during COVID-19, impacting vaccination rates

Trust in US physicians and hospitals dropped significantly during COVID-19, affecting vaccination rates across all demographics. Restoring trust is crucial for future public health efforts.

1 Aug 2024

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Researchers discovered diverse and stable immune cell populations in the upper respiratory tract, highlighting the critical role of mucosal immunity in COVID-19 and other respiratory diseases.

1 Aug 2024

Uncontrolled hypertension: A persistent threat to global health

In the United States and worldwide, cardiovascular disease is the leading avoidable cause of premature death and disability. Primarily heart attacks and stroke, cardiovascular disease accounts for more than 900,000 annual deaths nationally and about 10 million deaths globally.

1 Aug 2024

$Study reveals obesity's impact on muscle structure in heart failure with preserved ejection fraction$

Study reveals obesity's impact on muscle structure in heart failure with preserved ejection fraction

A new small study led by Johns Hopkins Medicine researchers and published July 25th in the journal Nature Cardiovascular Research has revealed the impact of obesity on muscle structure in patients having a form of heart failure called heart failure with a preserved ejection fraction (HFpEF).

1 Aug 2024

INTEGRA Biosciences' pipettes are endorsed by ergonomics champion iHEALTH 360

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From INTEGRA Biosciences 1 Aug 2024

Hamster sera study reveals Omicron subvariants' vast antigenic diversity

Study developed an antigenic map of SARS-CoV-2 variants using hamster sera, revealing substantial antigenic variation among Omicron subvariants and highlighting their distinct immune escape capabilities.

1 Aug 2024

COVID-19 significantly increases risk of hearing loss in young adults, study finds

Young adults with COVID-19 face a significantly higher risk of hearing loss and sudden sensorineural hearing loss. Researchers urge awareness and further investigation into COVID-19-related auditory damage.

31 Jul 2024

Advanced technology and AI used to diagnose rare diseases and birth abnormalities

Researchers at London Health Sciences Centre (LHSC) and Lawson Health Research Institute are using advanced technology and artificial intelligence (AI) to diagnose rare diseases and prenatal exposure-related birth abnormalities in two studies published today in American Journal of Human Genetics and Genetics in Medicine.

31 Jul 2024

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

Neurodivergent traits in childhood double the risk of chronic disabling fatigue by age 18, with inflammation playing a significant mediating role. This highlights the importance of addressing inflammatory markers in managing the health of neurodivergent individuals.

31 Jul 2024

Wildlife species show high SARS-CoV-2 exposure linked to human activity

Researchers found SARS-CoV-2 RNA in six wildlife species and higher seroprevalence in high human activity areas. Seven new human-to-animal transmission events of the Omicron variant were identified.

30 Jul 2024

Penn researchers find a way to tease apart genetic and environmental effects of disease risk

Every disease is shaped by a genetic component as well as environmental factors like air pollution, climate and socioeconomic status.

30 Jul 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Study reveals curcumin’s antidepressant effects in obese type 2 diabetes patients

A randomized clinical trial (RCT) to investigate the effectiveness of curcumin in lowering depression among obese individuals with diabetes mellitus type 2 (T2DM).

30 Jul 2024

Wearing surgical face masks in public spaces reduces the risk of self-reported respiratory symptoms

A team of Norwegian researchers conducted a pragmatic randomized trial to examine whether wearing surgical face masks while in public spaces resulted in a lower incidence of self-reported respiratory infection symptoms than not wearing a face mask.

29 Jul 2024

Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

29 Jul 2024

Ventilation must go beyond open windows to prevent airborne diseases, experts urge

Proper ventilation is crucial for preventing airborne transmission of pathogens, highlighting the need for better building design and public health guidelines post-COVID-19.

28 Jul 2024

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

Allogeneic hematopoietic cell transplantation (HCT) is a commonly used curative therapy for individuals with inborn errors of immunity (IEI).

28 Jul 2024

COVID pandemic accelerated brain aging, especially in males and deprived groups

The COVID-19 pandemic accelerated brain aging, particularly in males and those from deprived backgrounds, with significant cognitive performance decline in infected individuals. This impact was observed regardless of COVID-19 infection status, highlighting the role of psychosocial stressors.

25 Jul 2024

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Syndrome News and Research

FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

Olympic athletes overcome health challenges to reach the pinnacle of their sport

Trust in US physicians and hospitals plummeted during COVID-19, impacting vaccination rates

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Uncontrolled hypertension: A persistent threat to global health

Study reveals obesity's impact on muscle structure in heart failure with preserved ejection fraction

INTEGRA Biosciences' pipettes are endorsed by ergonomics champion iHEALTH 360

Hamster sera study reveals Omicron subvariants' vast antigenic diversity

COVID-19 significantly increases risk of hearing loss in young adults, study finds

Advanced technology and AI used to diagnose rare diseases and birth abnormalities

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

Wildlife species show high SARS-CoV-2 exposure linked to human activity

Penn researchers find a way to tease apart genetic and environmental effects of disease risk

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Study reveals curcumin’s antidepressant effects in obese type 2 diabetes patients

Wearing surgical face masks in public spaces reduces the risk of self-reported respiratory symptoms

Overcoming cancer relapse with CAR-Enhancer therapy

Ventilation must go beyond open windows to prevent airborne diseases, experts urge

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

COVID pandemic accelerated brain aging, especially in males and deprived groups

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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