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New software to help researchers study specific information about proteins

What if scientists could create more effective drugs to treat cancers and other diseases by better targeting specific sites on proteins in the body?

11 Dec 2019

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

UCLA scientists have discovered one reason why autoimmune diseases are more prevalent in women than in men.

11 Dec 2019

Researchers develop new bio-platform to hear the beat of small clusters of cells

One of the tests that almost every patient must face before a surgery or other health intervention is an electrocardiogram.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Help for teenagers who want to quit smoking

A new study published in the journal JAMA Pediatricsreports on the use of varenicline, a drug that helps smokers quit. The study is unique in that it targeted teenagers who wanted to quit. While confirming the low overall efficacy of the drug, it shows that it may perhaps help teenage smokers to quit faster and to stay smoke-free longer.

11 Dec 2019

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Addictions and drug interactions common among patients not disclosing their medication history

Some patients skip telling their doctors about the drugs and medications they are consuming. A new study shows that these patients are at a greater risk of unpleasant and sometimes dangerous drug-drug interactions as well as addictions. The study was published in the latest issue of The Journal of the American Osteopathic Association. The study is titled, “Role of opioid-involved drug interactions in chronic pain management”.

11 Dec 2019

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

A new study based on Veterans Affairs health records finds that non-drug therapies given to military service members with chronic pain may reduce the risk of long-term adverse outcomes, such as alcohol and drug disorder and self-induced injuries, including suicide attempts.

11 Dec 2019

Chemical found in tropical flower could help to treat deadly pancreatic cancer

An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat deadly pancreatic cancer.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.

11 Dec 2019

New therapy shows dramatic effect against worst types of leukaemias

A collaborative research effort by Australian and US scientists has led to the discovery of a promising new approach to treating some of the worst types of leukaemia, including an aggressive leukaemia that mostly affects babies.

11 Dec 2019

Researchers develop spray gel for frostbite injuries

Mountaineers and winter sports enthusiasts know the dangers of frostbite -- the tissue damage that can occur when extremities, such as the nose, ears, fingers and toes, are exposed to very cold temperatures. However, it can be difficult to get treated quickly in remote, snowbound areas.

11 Dec 2019

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.

11 Dec 2019

Blood pressure drug could be beneficial in treating alcohol use disorders

A drug used to treat high blood pressure may alleviate anxiety induced by long-term heavy alcohol use, and also halt the damage such drinking can cause to the brain's ability to grow new cells, research at the Queensland University of Technology shows.

11 Dec 2019

Researchers use stem cells to create in-vitro 3D neural tissue model

Researchers at the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer living biohybrid nerve tissue to develop 3D models of neural networks with the hopes of gaining a better understanding of how the brain and these networks work.

11 Dec 2019

FDA checks metformin drugs for potentially carcinogenic substance

The FDA is checking metformin medications used to treat diabetes for a potential carcinogen, N-nitrosodimethylamine (NDMA).

11 Dec 2019

Blood test could be a better way of guiding treatment for advanced breast cancer patients

A blood test can help identify rare mutations in advanced breast cancer, which may enable patients to access effective treatments more quickly in the future, Cancer Research UK scientists have found.

11 Dec 2019

Quick and simple method for identifying illicit drugs in powdered mixtures

The composition of suspicious powders that may contain illicit drugs can be analyzed using a quick and simple method called magneto-Archimedes levitation, according to a new study published in the journal Angewandte Chemie.

11 Dec 2019

Clinical trial eligibility criteria may be excessive, needlessly excluding patients

Federal regulations may keep lung cancer patients out of clinical trials simply because these patients are on medications that might affect the electrical system of the heart. Drilling into the details quickly turns up reasons to think these regulations may be preventing a substantial proportion of patients from participating in clinical trials.

10 Dec 2019

Drugs News and Research

New software to help researchers study specific information about proteins

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

Researchers develop new bio-platform to hear the beat of small clusters of cells

New drug combo promises help for triple negative breast cancer patients

Help for teenagers who want to quit smoking

Experimental Alzheimer’s drugs show promise

Addictions and drug interactions common among patients not disclosing their medication history

Non-drug therapies may reduce adverse outcomes in service members with chronic pain

Chemical found in tropical flower could help to treat deadly pancreatic cancer

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

New therapy shows dramatic effect against worst types of leukaemias

Researchers develop spray gel for frostbite injuries

Treatment combination improves survival in advanced HER2-positive breast cancer patients

Blood pressure drug could be beneficial in treating alcohol use disorders

Researchers use stem cells to create in-vitro 3D neural tissue model

FDA checks metformin drugs for potentially carcinogenic substance

Blood test could be a better way of guiding treatment for advanced breast cancer patients

Quick and simple method for identifying illicit drugs in powdered mixtures

Clinical trial eligibility criteria may be excessive, needlessly excluding patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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