B Cell News and Research

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Identification of common genes in COVID-19 and COPD

Based on protein-protein interactions, the paper shows the presence of ten genes that overlap between the two illnesses, also shared by several other deadly and debilitating diseases.

2 Nov 2021

Placental cell-type productively infected with SARS-CoV-2

A new preprint describes the development of a new platform for evaluating the risk of SARS-CoV-2 infection in placental tissue.

2 Nov 2021

SARS-CoV-2 variants neutralized by camel nanobodies

Researchers from the US recently isolated two VHH nanobodies - 7A3 and 8A2 - from dromedary camels (Camelus dromedaries) using phage display. These nanobodies were found to have a high affinity for the spike RBD and broad neutralization abilities against SARS-CoV-2 and its variants.

2 Nov 2021

Scientists identify compound that shows potential in easing the symptoms of coronavirus infections

By studying a disease caused by a close cousin of the virus behind COVID-19, a team of scientists has identified a compound that shows potential in easing the symptoms of coronavirus infections.

1 Nov 2021

Researchers identify γ-tubulin ring complex to be responsible for providing centriole stability

Centrioles are cylindrical structures involved in the generation of microtubules - fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

1 Nov 2021

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the COVID-19 vaccine was not associated with severe disease flares in patients with rheumatic diseases.

1 Nov 2021

Evidence antibodies targeting HCoV-OC43 are robustly boosted in response to SARS-CoV-2 but not vaccination

The magnitude of cross-reactive antibodies correlated well with responses to the SARS-CoV-2 spike protein and the S2 subdomain.

1 Nov 2021

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Their tickets were booked. Their schedules were set. The students were finally going to test their product on real people. But in July, Sierra Leone's COVID-19 level spiked almost overnight, and Lehigh's Sickle Cell Anemia Diagnostic Device team lost yet another opportunity to conduct fieldwork.

1 Nov 2021

Investigation of Budesonide's mechanism of action against SARS-CoV-2

Researchers look to gain an understanding of the mechanism of action of budesonide in improving the prognosis of patients with SARS-CoV-2 infection.

1 Nov 2021

Potential link between SARS-CoV-2 infection and secondary occurrence of anti-NMDAR encephalitis

Scientists explore the link between SARS-CoV-2 infection and anti-NMDAR encephalitis.

1 Nov 2021

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

The researchers investigated the neutralizing activity of turmeric root extract, curcumin-containing capsules, and pure curcumin against SARS-CoV-2.

1 Nov 2021

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences.

1 Nov 2021

Identification of novel nanobodies to specifically target SARS-CoV-2 replication protein

Researchers have recently identified two nanobodies that show specific binding against a SARS-CoV-2 replication protein.

1 Nov 2021

Study finds inhaled microspheres reduce SARS-CoV-2 infective effectiveness

A new study develops an inhaled microfluidic microsphere with a genetically engineered membrane from the ACE2 receptor-overexpressing cells and macrophages.

1 Nov 2021

Researchers generate and characterize the hepatic organoid culture system

Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments.

1 Nov 2021

$Non-thermal atmospheric pressure plasma heals bone fractures in animal bone defect models$

Non-thermal atmospheric pressure plasma heals bone fractures in animal bone defect models

Recent technological innovations which have allowed plasma to be generated at room temperature and at ambient atmosphere in what is called non-thermal atmospheric pressure plasma (NTAPP) have given scientists from Japan the opportunity to apply the therapeutic properties of this "fourth state of matter" to bone regeneration.

1 Nov 2021

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

A team of international scientists has recently identified a distinct set of proinflammatory mediators and metabolites associated with the fatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, they have established a link between gut microbiome alteration and hyper-inflammatory response in patients with severe COVID-19. The study is currently available on the bioRxiv* preprint server.

1 Nov 2021

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

A recent study published in the journal Cellular & Molecular Immunology shows that a new A.30 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can evade vaccine-induced antibodies and might spread outside the lungs extraordinarily well, with important implications for our public health response.

1 Nov 2021

The impact of SARS-CoV-2 variants on the COVID-19 epidemic in South Africa

A new study explores the role of new SARS-CoV-2 variants in sustaining the pandemic in South Africa.

31 Oct 2021

The ability of natural flavonoids to inhibit SARS-CoV-2

A recent systematic review discusses naturally occurring flavonoids as a promising antiviral alternative against SARS-CoV-2.

31 Oct 2021

B Cell News and Research

Identification of common genes in COVID-19 and COPD

Placental cell-type productively infected with SARS-CoV-2

SARS-CoV-2 variants neutralized by camel nanobodies

Scientists identify compound that shows potential in easing the symptoms of coronavirus infections

Researchers identify γ-tubulin ring complex to be responsible for providing centriole stability

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

Evidence antibodies targeting HCoV-OC43 are robustly boosted in response to SARS-CoV-2 but not vaccination

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Investigation of Budesonide's mechanism of action against SARS-CoV-2

Potential link between SARS-CoV-2 infection and secondary occurrence of anti-NMDAR encephalitis

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Identification of novel nanobodies to specifically target SARS-CoV-2 replication protein

Study finds inhaled microspheres reduce SARS-CoV-2 infective effectiveness

Researchers generate and characterize the hepatic organoid culture system

Non-thermal atmospheric pressure plasma heals bone fractures in animal bone defect models

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

The impact of SARS-CoV-2 variants on the COVID-19 epidemic in South Africa

The ability of natural flavonoids to inhibit SARS-CoV-2

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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