Inflammation News and Research

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Study focuses on effects of nanoparticles on eosinophils linked to inflammation

In a growing number of industries, workers are often unknowingly exposed to nanoparticles (NPs). Do they enter the body? Could they have an impact on health? Professor Denis Girard from the INRS-Institut Armand-Frappier Research Centre has had the foresight to study the potential toxicity of a wide variety of NPs with a view to setting the record straight before problems occur.

4 Dec 2013

Researchers analyze protective effects of mild hypothermia on CNS injuries

There are few data on the effectiveness and mechanism underlying mild hypothermia in the treatment of central nervous system injuries. Therefore, there is a need to investigate the potentially beneficial effects of mild hypothermia on central nervous system injuries.

4 Dec 2013

Research: Omega-3 fatty acids in dietary supplements can cross blood brain barrier in Alzheimer's patients

New research from Karolinska Institutet in Sweden shows that omega-3 fatty acids in dietary supplements can cross the blood brain barrier in people with Alzheimer's disease, affecting known markers for both the disease itself and inflammation.

4 Dec 2013

Newly discovered receptor may help in early diagnosis and treatment for sepsis

Sepsis, or septicaemia, is a devastating disease that is difficult to diagnose early and for which treatment options are limited. The number of deaths from sepsis exceeds those from lung cancer, and from breast and bowel cancer combined.

4 Dec 2013

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

Scientists have moved a step closer to an "obesity drug" that may block the effects of diets high in sugar and fats. In a new research report published in the December 2013 issue of The FASEB Journal, scientists show that there is an abnormal amount of an inflammatory protein called PAR2 in the abdominal fat tissue of overweight and obese humans and rats.

3 Dec 2013

Oxygen levels play critical role in determining effectiveness of anti-inflammatory drugs

A new research discovery published in the December 2013 issue of the Journal of Leukocyte Biology yields an important clue toward helping curb runaway inflammation. Oxygen levels play a critical role in determining the severity of the inflammatory response and ultimately the effectiveness of anti-inflammatory drugs.

3 Dec 2013

BAL findings boost non-smoking COPD distinction

Research shows that smoking status, and not airway obstruction, determines the distribution of T cell subsets in bronchoalveolar lavage in patients with chronic obstructive pulmonary disease.

2 Dec 2013

Government of Canada awards $8.76M in funding to develop cure for HIV

In the push for a cure for HIV, the Government of Canada has announced $8.76 million in funding to Université de Montréal and Institut de recherches cliniques de Montréal Professor éric A. Cohen, who will lead an unrivaled group of Canadian investigators and international collaborators with a strong track record of interactive research.

29 Nov 2013

Scientists identify new approach to fight malaria parasites

Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking the parasites that cause malaria.

28 Nov 2013

Pediatric dermatologists offer tips for treating skin ailments

As parents across the Chicago area prepare to take that perfect holiday photo to send to family and friends, they may want to consider more than just getting their kids to smile and look at the camera.

28 Nov 2013

Loyola dermatologist offers skin care tips for holidays

The holidays often bring freezing temperatures, limited sleep, sugary treats and cocktails. This combination can spell trouble for your skin, according to a dermatologist at Loyola University Health System.

28 Nov 2013

NIBIB-funded researchers explore better treatment for brain aneurysms

Thirty thousand Americans suffer severe neurological damage or death from brain aneurysms each year and the existing treatments eventually fail in nearly half of patients. Currently, these "bubbles" in the blood vessel are either clamped off, which requires invasive brain surgery, or filled with platinum coils to induce clotting in the aneurysm. Both treatments, although somewhat effective, can have subsequent problems, including inflammation, incomplete healing, and the development of secondary aneurysms adjacent to the initial site. These complications result in approximately 40 percent of patients needing additional treatment to attempt to re-repair the aneurysm.

28 Nov 2013

Cedars-Sinai researchers design new procedure to treat stem cell-related corneal blindness

Researchers in the Cedars-Sinai Regenerative Medicine Institute have designed and tested a novel, minute-long procedure to prepare human amniotic membrane for use as a scaffold for specialized stem cells that may be used to treat some corneal diseases.

27 Nov 2013

Probiotic drink changes reaction of cells lining nasal passages of hay fever sufferers

A study has shown that a daily probiotic drink changed how cells lining the nasal passages of hay fever sufferers reacted to a single out-of-season challenge. However, it did not lead to significant changes in hay fever symptoms, although this challenge test may not have accurately represented natural allergen exposure.

27 Nov 2013

Bioxodes completes seed funding round to bring Ir-CPI product into pre-clinical development

Bioxodes SA, a company developing products derived from natural sources, has completed a EUR 2.6 million (USD 3.5 million) first seed funding round with a consortium of business angels and Belgian investment funds. EUR 1.6 million is from the European Regional Development Fund and the Walloon Region in Belgium via the Retech program for Research and Technology. It will be used to bring the company’s lead product Ir-CPI into pre-clinical development over the next 18 months.

27 Nov 2013

Researchers find that hay fever and allergies make migraines worse

People with migraine who also battle allergies and hay fever (rhinitis) endure a more severe form of headaches than their peers who struggle with migraine, but aren't affected by the seasonal or year-round sniffles, according to researchers from the University of Cincinnati, Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University and Vedanta Research.

26 Nov 2013

Risk factors for Alzheimer's disease

Alzheimer's disease has joined cancer at the top of the list of feared diagnoses, and although Alzheimer's does have the potential to devastate millions of patients and families, there are reasons for hope - and possibly opportunities to reduce risk or alter the course of disease progression, according to Keith Black, MD, professor and chair of the Department of Neurosurgery at Cedars-Sinai.

26 Nov 2013

Researchers reveal why some breast cancer cells are resistant to chemotherapy

Researchers at the UNC School of Medicine, working with cell lines in a lab, have discovered why some of the most aggressive and fatal breast cancer cells are resistant to chemotherapy, and UNC scientists are developing ways to overcome such resistance.

26 Nov 2013

Researchers identify new mechanism that causes neurodegeneration

As we age, our body rhythms lose time before they finally stop. Breaking the body clock by genetically disrupting a core clock gene, Bmal1, in mice has long been known to accelerate aging , causing arthritis, hair loss, cataracts, and premature death.

26 Nov 2013

Icahn School of Medicine receives $2.7M to investigate narrow pathway targeted immune therapy

The National Institutes of Health has awarded a research team at the Icahn School of Medicine at Mount Sinai $2.7 million to study systemic treatments for patients with moderate to severe atopic dermatitis (AD), also known as eczema.

26 Nov 2013