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Oligomeric molecular structure of the MOR-Gal1R complex revealed

A study published in the journal Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids.

22 Jul 2022

Study opens up new possible treatment methods for patients with urinary tract infections

Patients who have indwelling urinary catheters often suffer from urinary tract infections, which can be difficult to treat.

22 Jul 2022

LJI study about common cold coronaviruses may offer clues to how immunity can build up against SARS-CoV-2

For a glimpse into the future of SARS-CoV-2 immunity, scientists at La Jolla Institute for Immunology (LJI) are investigating how the immune system builds its defenses against common cold coronaviruses (CCCs).

21 Jul 2022

Researchers discover a concise way to synthesize potent natural neurotoxin

Researchers have discovered a concise way to synthesize a "biosynthetic and ecological enigma" that has intrigued chemists and biologists for more than a century: tetrodotoxin (TTX), a potent natural neurotoxin commonly associated with pufferfish that is also used as a vital probe in neuroscience research.

21 Jul 2022

Study may help overcome some obstacles to the development of nanoparticle-based drugs

Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy.

21 Jul 2022

A different approach to build a more durable, broadly effective COVID-19 vaccine

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.

21 Jul 2022

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

Cancer cells produce small amounts of their own form of collagen, creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses, according to a new study by researchers at The University of Texas MD Anderson Cancer Center.

21 Jul 2022

Booster vaccination counters the severity of Omicron breakthrough infections

Researchers assessed a panel of seven SARS-CoV-2 vaccines currently available globally and in the United States and immunity acquired through the previous infection against all Omicron subvariants.

21 Jul 2022

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

The University of Texas MD Anderson Cancer Center and Obsidian Therapeutics, Inc. today announced Food and Drug Administration (FDA) clearance of an Investigational New Drug (IND) application for an MD Anderson-sponsored Phase I clinical study of OBX-115, Obsidian's lead engineered tumor infiltrating lymphocyte (TIL) therapy candidate.

21 Jul 2022

Pigment epithelium-derived factor ablations may lead to eye aging

Researchers identified that loss of pigment epithelium-derived factor (PEDF) may cause aging in the eye.

21 Jul 2022

Unlocking the power of proteins to better understand human health

We speak to Andrew Lynn, the chief executive at Fluidic Analytics, about the role proteins play in understanding human disease.

From Fluidic Analytics 21 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

High-level resistance of SARS-CoV-2 BA.4 against neutralizing antibodies

Researchers evaluates the sensitivity of BA.4 in both vaccinated and unvaccinated individuals infected with the SARS-CoV-2 variants.

20 Jul 2022

COVID vaccines induce memory B and T cells in primary antibody deficient patients

The SARS-CoV-2-specific B- and T-cell response post-COVID-19 primary and booster vaccination in primary antibody deficient patients.

20 Jul 2022

How the Omicron variant shifted the biology of SARS-CoV-2

Researchers discuss significant antigenic changes within the spike protein of new SARS-CoV-2 VOCs like the Omicron variant.

20 Jul 2022

Charged nanoparticles combined with a vaccine effective in eliminating melanoma tumors in mice

Cancers in humans have all sorts of ways to survive and thrive: Cells and tumors alike engage in devious means to deflect, deceive, and evade detection by our bodies’ immune systems.

20 Jul 2022

Stopping 'budding' viruses in their tracks

Paramyxoviruses have the potential to trigger a devastating pandemic. This family of viruses includes measles, Nipah virus, mumps, Newcastle disease and canine distemper.

20 Jul 2022

Scientists find a promising new combination therapy for certain types of lung tumors

Scientists at the Francis Crick Institute have found that using immunotherapy alongside a drug that blocks a common gene mutation in lung cancer could be a promising new combination therapy for certain types of lung tumors.

20 Jul 2022

Nanotherapeutic compound may help treat inflammation, brain injury in patients with severe COVID-19

An anti-inflammatory compound may have the potential to treat systemic inflammation and brain injury in patients with severe COVID-19 and significantly reduce their chances of death, according to a new study from UTHealth Houston and other institutions.

20 Jul 2022

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

Researchers introduced a phenotypic screening assay for identifying compounds with SARS-CoV-2 inhibition potential based on caspase 3/7 activation.

20 Jul 2022

Cell News and Research

Oligomeric molecular structure of the MOR-Gal1R complex revealed

Study opens up new possible treatment methods for patients with urinary tract infections

LJI study about common cold coronaviruses may offer clues to how immunity can build up against SARS-CoV-2

Researchers discover a concise way to synthesize potent natural neurotoxin

Study may help overcome some obstacles to the development of nanoparticle-based drugs

A different approach to build a more durable, broadly effective COVID-19 vaccine

Cancer cells produce small amount of collagen that impacts tumor microbiome and immunity

Booster vaccination counters the severity of Omicron breakthrough infections

FDA clears IND application for MD Anderson-sponsored Phase I clinical study of OBX-115 therapy

Pigment epithelium-derived factor ablations may lead to eye aging

Unlocking the power of proteins to better understand human health

Is monkeypox a global public-health emergency?

High-level resistance of SARS-CoV-2 BA.4 against neutralizing antibodies

COVID vaccines induce memory B and T cells in primary antibody deficient patients

How the Omicron variant shifted the biology of SARS-CoV-2

Charged nanoparticles combined with a vaccine effective in eliminating melanoma tumors in mice

Stopping 'budding' viruses in their tracks

Scientists find a promising new combination therapy for certain types of lung tumors

Nanotherapeutic compound may help treat inflammation, brain injury in patients with severe COVID-19

Scientists introduce SARS-CoV-2 phenotype screening for identifying novel antiviral drugs

What are the challenges of cell line development? eBook

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