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Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

A new study aimed to examine the antiviral potential of atovaquone against the original SARS-CoV-2 strain and other variants of concern.

25 Oct 2021

How pregnancy influences SARS-CoV-2 immune response

A focus article published in Science Translational Medicine highlighted two recently published studies that investigated the response of pregnant women to natural infections and COVID-19 vaccines.

25 Oct 2021

Role of SARS-CoV-2 infection biomarkers in HIV replication

A new study investigates the role of the S100A8/A9 complex in the replication of HIV.

25 Oct 2021

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Researchers isolated single cells among individuals with and without prior infection with the SARS-CoV-2 vaccinated with BNT162b2 mRNA vaccine and compared the nature of the neutralizing antibody response against the original Wuhan virus and the subsequent variants.

25 Oct 2021

Nanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack recovery in mouse model

A heart attack kills heart muscle cells, leading to a scar that weakens the heart, often leading to eventual heart failure. The lack of muscle repair is due to the very limited ability of mammalian heart muscle cells to proliferate, except for a brief period around birth.

25 Oct 2021

Scientists show how cold could alleviate multiple sclerosis symptoms

In evolutionary biology, the "Life History Theory", first proposed in the 1950s, postulates that when the environment is favorable, the resources used by any organism are devoted for growth and reproduction.

25 Oct 2021

Cancer patients have impaired antibody responses to COVID-19 mRNA vaccines

A new study posted to the medRxiv* preprint server studies the neutralizing antibody response in cancer patients diagnosed with chronic lymphocytic leukemia (CLL), lung cancer, breast cancer, and various non-Hodgkin’s lymphomas (NHL), post-reception of two doses of messenger RNA (mRNA) vaccines.

25 Oct 2021

New Spex Genomax 2050 accelerates the extraction of molecules

Obtain fast and efficient extraction of nucleic acids, proteins, and other molecules with the new Spex® Genomax® 2050; a high-throughput plant and animal tissue homogenizer and cell lyser designed for rapid cell disruption, cell lysis and tissue homogenization through bead beating.

From SPEX SamplePrep 25 Oct 2021

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

A new study examines the potential binding interaction of the beneficial components of Chaga mushroom with that of the SARS-CoV-2 RBD.

24 Oct 2021

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Researchers report the binding and pseudo-neutralizing antibody titers elicited after patients had received either the Pfizer-BioNTech or AstraZeneca vaccines.

24 Oct 2021

Mapping the molecular gene signatures of respiratory viruses, including SARS-CoV-2

Researchers compare a large cohort of transcriptomic dataset maps of gene regulation by SARS-CoV-2 infection.

24 Oct 2021

Health care costs for people with rare diseases have been underestimated, study shows

A new, retrospective study of medical and insurance records indicates health care costs for people with a rare disease have been underestimated and are three to five times greater than the costs for people without a rare disease.

22 Oct 2021

Fluorescent system reveals how viruses produced during RSV infection change shape

Respiratory syncytial virus, more commonly known as RSV, is a highly contagious respiratory virus that can be very serious and even fatal for young children and the elderly.

22 Oct 2021

Researchers unravel the molecular origins of recombination in RNA viruses

An international consortium, led by Delft University of Technology and the University of North Carolina, has for the first time succeeded in probing the molecular origins of recombination in RNA viruses.

22 Oct 2021

Gene therapy strategy against Angelman syndrome shows early promise

Scientists at the UNC School of Medicine have reported in the journal JCI Insight encouraging early tests of a gene therapy strategy against Angelman syndrome, a neurodevelopmental disorder that features poor muscle control and balance, hard-to-treat epilepsy, and intellectual disabilities.

22 Oct 2021

B Cell News and Research

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

How pregnancy influences SARS-CoV-2 immune response

Role of SARS-CoV-2 infection biomarkers in HIV replication

Study suggests seropositive individuals produce anti-SARS-CoV-2 antibodies with improved potency and breadth

Nanoparticle-mediated, slow-release delivery of TT-10 enhances heart attack recovery in mouse model

Scientists show how cold could alleviate multiple sclerosis symptoms

Cancer patients have impaired antibody responses to COVID-19 mRNA vaccines

New Spex Genomax 2050 accelerates the extraction of molecules

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Mapping the molecular gene signatures of respiratory viruses, including SARS-CoV-2

Health care costs for people with rare diseases have been underestimated, study shows

Fluorescent system reveals how viruses produced during RSV infection change shape

Researchers unravel the molecular origins of recombination in RNA viruses

Gene therapy strategy against Angelman syndrome shows early promise

Researchers identify mechanism behind insufficient treatment efficacy of psoriasis drugs

New method for safe engineering of therapeutic cells with photothermal nanofibers

Montana tribes want to stop jailing people for suicide attempts but lack a safer alternative

Study shows immune profile heterogeneity amongst healthy adults

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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