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Delaying rheumatoid arthritis treatment could greatly increase likelihood of joint damage

Delaying treatment for rheumatoid arthritis could greatly increase the likelihood that patients will suffer joint damage and experience disability two years out, according to a new study from Vivian Bykerk, M.D. at Hospital for Special Surgery. The research will be presented at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals on October 28 in San Diego.

28 Oct 2013

Combination of three DMARDs more cost-effective in treating early rheumatoid arthritis

Starting with a combination of three traditional disease-modifying antirheumatic drugs (called DMARDs) for treating early rheumatoid arthritis is more cost-effective long term, with comparable benefits, than using either an immediate or step-up approach with anti-tumor necrosis factor (called Anti-TNFs) drugs and methotrexate, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Apremilast drug shows promise for Behcet's ulcers

Apremilast, an orally available small molecule modulating several inflammatory pathways, which is pending approval by the United States Food and Drug Administration, is showing promise in the treatment of mouth and genital ulcers in people with Behcet's syndrome, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Diego.

28 Oct 2013

Anti-tumor necrosis factor drugs modestly reduce risk of acute coronary syndrome

Tumor necrosis factor inhibitor drugs (commonly called Anti-TNFs) modestly reduce the risk of acute coronary syndrome, such as heart attacks and angina, in rheumatoid arthritis patients whose inflammation places them at higher risk of developing coronary heart disease, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Two aggressive therapy approaches effective for children with juvenile idiopathic arthritis

Children with juvenile idiopathic arthritis who receive early, aggressive therapy with a combination of medications achieve clinical inactive disease status faster than they would with less aggressive therapy, according to new research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Patients with severe rheumatoid arthritis more likely to have heart problems

People with rheumatoid arthritis and other chronic inflammatory conditions are at higher risk of heart disease. Who is in the most danger, why and how best to prevent and detect cardiovascular complications are important questions for physicians and researchers.

28 Oct 2013

International researchers identify 11 new genes linked to Alzheimer's disease

An international group of researchers has identified 11 new genes that offer important new insights into the disease pathways involved in Alzheimer's disease. The highly collaborative effort involved scanning the DNA of over 74,000 volunteers-the largest genetic analysis yet conducted in Alzheimer's research-to discover new genetic risk factors linked to late-onset Alzheimer's disease, the most common form of the disorder.

28 Oct 2013

UL research aims to improve diagnosis and management of delirium among palliative care patients

University of Limerick researchers have been awarded €175,000 to undertake research which aims to improve diagnosis and management of delirium, dementia and depression among palliative care patients.

28 Oct 2013

Scientists develop new drug to treat obstructive airway diseases

Scientists have developed a new drug (RPL554) that could treat obstructive airway diseases such as asthma and chronic obstructive pulmonary disease in two ways at once, according to new research published in The Lancet Respiratory Medicine.

25 Oct 2013

Research brings hope of new treatment for asthma patients resistant to corticosteroids

New research from Japan brings hope of a new treatment for asthma patients resistant to corticosteroids. In a study published today in the journal Nature Communications, researchers from the RIKEN Center for Integrative Medical Sciences and Keio University in Japan report that a type of lymphocytes called natural helper ells plays a critical role in corticosteroid resistance and demonstrate that the anti-psychotic drug Pimozide can be used to overcome resistance to steroids in severe asthma patients.

25 Oct 2013

HIV-positive patients with high CD4 cell counts are not at increased risk for heart attacks

Patients who are HIV-positive and have high CD4 cell counts - or have a high number of white blood cells that fight infections - aren't at an increased risk for heart attacks compared to patients who are HIV-negative, according to a Kaiser Permanente study that appears in the current online issue of the Journal of Acquired Immune Deficiency Syndromes.

25 Oct 2013

Type 1 diabetes modifies communication between central nervous system and bone marrow

A new University of Sydney study has found that having Type 1 diabetes alters the normal communication between the human central nervous system and bone marrow, causing inflammatory effects and further disease.

24 Oct 2013

Researchers discover potential method to identify TBI using positron PET scans

Accurately diagnosing traumatic brain injuries (TBI) and concussions is difficult, as standard CT or MRI scans can't see most changes to the brain caused by these injuries.

24 Oct 2013

Leukemia drug reverses symptoms of colitis in lab tests

A drug currently on the market to treat leukemia reversed symptoms of colitis in lab tests, according to recently published findings by medical researchers with the University of Alberta.

24 Oct 2013

Researchers reveal why sleep deprivation increases risk of cardiovascular disease, type 2 diabetes

The fact that sleep deprivation has an impact on the function of the human immune system is well known. In their latest study, the University of Helsinki research group Sleep Team has now discovered new biological links between sleep loss and the immune system. The results provide at least a partial explanation of why sleep deprivation increases the risk of cardiovascular disease and type 2 diabetes.

24 Oct 2013

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Research from Boston University School of Medicine suggests that testosterone treatment in hypogonadal (testosterone deficient) men restores normal lipid profiles and may reduce the risk of cardiovascular disease. These finding currently appear online in the International Journal of Clinical Practice.

24 Oct 2013

Inflammation causally linked to functional decline in aging

Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer's, and diabetes. But according to a Yale School of Medicine study, even in the absence of a disease, inflammation can lead to serious loss of function throughout the body, reducing healthspan - that portion of our lives spent relatively free of serious illness and disability.

23 Oct 2013

Promising technique for treating eye disease proves effective in preclinical studies

A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, California.

23 Oct 2013

Angiochem presents results of Phase 2 study with ANG1005 in breast cancer patients with brain metastases

Angiochem, a clinical stage biotechnology company developing drugs that are uniquely capable of crossing the blood-brain barrier (BBB), announced that the complete analysis results of a Phase 2 clinical study with ANG1005, a novel paclitaxel-peptide drug conjugate, in breast cancer patients with brain metastasis were presented today at the 2013 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference.

23 Oct 2013

COPD treatments: an interview with Professor Price, University of Aberdeen

The first thing is that we can’t cure COPD. The problem we have with COPD is that the process itself is not treatable, certainly not once it gets to the extent that it’s advanced.

22 Oct 2013

Inflammation News and Research

Delaying rheumatoid arthritis treatment could greatly increase likelihood of joint damage

Combination of three DMARDs more cost-effective in treating early rheumatoid arthritis

Apremilast drug shows promise for Behcet's ulcers

Anti-tumor necrosis factor drugs modestly reduce risk of acute coronary syndrome

Two aggressive therapy approaches effective for children with juvenile idiopathic arthritis

Patients with severe rheumatoid arthritis more likely to have heart problems

International researchers identify 11 new genes linked to Alzheimer's disease

UL research aims to improve diagnosis and management of delirium among palliative care patients

Scientists develop new drug to treat obstructive airway diseases

Research brings hope of new treatment for asthma patients resistant to corticosteroids

HIV-positive patients with high CD4 cell counts are not at increased risk for heart attacks

Type 1 diabetes modifies communication between central nervous system and bone marrow

Researchers discover potential method to identify TBI using positron PET scans

Leukemia drug reverses symptoms of colitis in lab tests

Researchers reveal why sleep deprivation increases risk of cardiovascular disease, type 2 diabetes

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Inflammation causally linked to functional decline in aging

Promising technique for treating eye disease proves effective in preclinical studies

Angiochem presents results of Phase 2 study with ANG1005 in breast cancer patients with brain metastases

COPD treatments: an interview with Professor Price, University of Aberdeen

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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