Lungs News and Research

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Johns Hopkins-designed animal tuberculosis "tracker" to speed drug and vaccine studies

Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.

23 Jul 2009

Some blood pressure drugs may help protect against dementia, study shows

A particular class of medication used to treat high blood pressure could protect older adults against memory decline and other impairments in cognitive function, according to a newly published study from Wake Forest University School of Medicine.

23 Jul 2009

Miglustat shows promise for cystic fibrosis

Miglustat is a drug currently under phase 2 clinical trials on patients suffering from cystic fibrosis (1). Its potential for treating the disease was discovered in 2006 thanks to the work of Frédéric Becq's team at the Institute of Cell Physiology and Biology (CNRS/Université de Poitiers), funded by the associations Vaincre la Mucoviscidose, MucoVie66, La Pierre Le Bigaut and ABCF2.

21 Jul 2009

Rates of secondhand smoke exposure high among college students

Secondhand smoke (SHS) is not only a nuisance, but a potential health concern for many college students, and administrators should be taking steps to reduce students' exposure, according to a new study by researchers at Wake Forest University School of Medicine.

21 Jul 2009

UT Southwestern Medical Center grant aids study of lung cancer in people who never smoked

Researchers at UT Southwestern Medical Center are among an elite group of cancer scientists to share a $2 million grant to find biomarkers for lung cancer that develops in people who have never smoked.

21 Jul 2009

Discovery of new molecular pathway for targeting cancer

A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach.

20 Jul 2009

New drug compound Salirasib brings hope to pancreatic cancer patients

Every year, 42,000 Americans are diagnosed with pancreatic cancer. Few live very long, and less than 5% are still alive five years after diagnosis.

20 Jul 2009

Researchers discover how flu damages lung tissue

A protein in influenza virus that helps it multiply also damages lung epithelial cells, causing fluid buildup in the lungs, according to new research from the University of Alabama at Birmingham (UAB) and Southern Research Institute . Publishing online this week in the journal of the Federation of American Societies for Experimental Biology, the researchers say the findings give new insight into how flu attacks the lungs and provides targets for new treatments.

19 Jul 2009

Thalidomide does not improve survival in small cell lung cancer

Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, according to a new study published online July 16 in the Journal of the National Cancer Institute.

17 Jul 2009

Depression and stress worsen childhood asthma

Young people with asthma have nearly twice the incidence of depression compared to their peers without asthma, and studies have shown that depression is associated with increased asthma symptoms and, in some cases, death.

17 Jul 2009

Cystic fibrosis medicines that help to break down mucus in the lungs may carry an unexpected long-term benefit

Cystic fibrosis medicines that help to break down mucus in the lungs may carry an unexpected long-term benefit, a study suggests.

16 Jul 2009

Obama announces Regina Benjamin as Surgeon General pick

Dr. Regina Benjamin is President Obama's pick for surgeon general. The Alabama family physician has been an advocate for universal care, and is expected to have a role "at the table" in health reform, which would be an unusual degree of influence over policy for a surgeon general. Obama said Benjamin "represents what's best about health care in America."

15 Jul 2009

Discovery of brain-protecting protein

Johns Hopkins researchers have discovered a novel protein that can protect brain cells by interrupting a naturally occurring "stress cascade" resulting in cell death.

14 Jul 2009

Dramatic drop in deaths from most common cancers

The death toll from three of the UK's most common cancers has dropped to its lowest level for almost 40 years* - according to new figures released by Cancer Research UK.

12 Jul 2009

Stress and depression worsen childhood asthma

12 Jul 2009

Environmental manganese and cancer mortality rates

In the first ecological study of its kind in the world, a Wake Forest University Baptist Medical Center researcher has uncovered the unique finding that groundwater and airborne manganese in North Carolina correlates with cancer mortality at the county level.

9 Jul 2009

Blacks with equal care still more likely to die of some cancers

"African Americans are less likely than whites to survive breast, prostate and ovarian cancer even when they receive equal treatment, according to a large study that offers provocative evidence that biological factors play a role in at least some racial disparities," the Washington Post reports.

8 Jul 2009

Costliest Medicare markets in Florida, New York, California

U.S. News & World Report examines cost, frequency, and outcomes studies on Medicare patients from the Dartmouth Institute for Health Policy and Clinical Practice : "The Dartmouth research is particularly relevant to older Americans because it is based to a large extent on Medicare data, involving patients ages 65 and older.

8 Jul 2009

New strategies to improve treatment and prevent heart failure in children

Structural cardiovascular abnormalities present at birth are the leading cause of heart failure in children. Nearly half a million children in the United States have structural heart problems ranging in severity from relatively simple issues, such as small holes between chambers of the heart, to very severe malformations, including complete absence of one or more chambers or valves.

7 Jul 2009

Researchers profile genes in acutely ill idiopathic pulmonary fibrosis patients

The first findings from a one-of-a-kind, patient-driven effort to provide lung tissue for research might help doctors predict when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill and also could point the way to interventions that could sustain them until life-saving transplants can be performed.

7 Jul 2009