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Study confirms impact of febrile neutropenia on chemotherapy delivery in NHL

Data presented at the 15th European Hematology Association (EHA) congress in Barcelona, highlights the impact of febrile neutropenia (FN) on chemotherapy delivery in non-Hodgkin lymphoma (NHL) patients. The IMPACT NHL study showed that unplanned hospitalisations, delays in chemotherapy and reductions of chemotherapy dose leading to suboptimal relative dose intensity (RDI) of chemotherapy were more frequent in patients who experienced FN than those who did not.

14 Jun 2010

Discarded livers have potential to be reengineered into usable replacement organs: Researchers

A team led by researchers from the Center for Engineering in Medicine at Massachusetts General Hospital has developed a technique that someday may allow growth of transplantable replacement livers. In their report that will be published in Nature Medicine and is receiving early online release, the investigators describe using the structural tissue of rat livers as scaffolding for the growth of tissue regenerated from liver cells introduced through a novel reseeding process.

14 Jun 2010

Researchers identify 2,630 proteins that reside in human spinal fluid

A research team has sharply expanded scientific knowledge of the composition of human spinal fluid. The researchers have identified 2,630 proteins that reside in fluid that is considered "normal," a number nearly three times as great as the total number of proteins previously identified. Another striking finding was that more than half (56%) of the proteins were relatively unique to the spinal fluid and not found in blood.

14 Jun 2010

Cook Medical files for PMA of Zilver PTX Drug-Eluting Peripheral Stent with FDA

Cook Medical has submitted its Pre-Market Approval (PMA) application to the U.S. Food and Drug Administration (FDA) for the company's unique polymer-free Zilver® PTX® Drug-Eluting Peripheral Stent. Intended for use in patients with peripheral arterial disease (PAD) in the superficial femoral artery (SFA), Zilver PTX is a self-expanding, highly durable nitinol stent that uses a proprietary, polymer-free technology to deliver a locally therapeutic dose of paclitaxel, an antiproliferative drug, to the target lesion.

11 Jun 2010

Study on health disparities and sexual orientation

A recent study conducted by Northeastern University's Institute on Urban Health Research found a significant number of health disparities in Massachusetts between heterosexual adults and gay, lesbian and bisexual adults.

11 Jun 2010

AVEO Pharmaceuticals presents tivozanib’s Phase 2 trial data at ASCO meeting

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today announced data from a subgroup analysis of a Phase 2 randomized discontinuation trial showing that the median progression-free survival (PFS) achieved by patients with advanced clear cell renal cell carcinoma (RCC) who had undergone a prior nephrectomy was 14.8 months.

11 Jun 2010

Study offers new insights into how brain chooses between behaviors that are critical for survival

A team of biologists has isolated genes that regulate the sleep-feeding conflict. The study, which appears in the latest issue of the journal Current Biology, offers new insights into how the brain chooses between behaviors that are critical for survival.

11 Jun 2010

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

The p53 gene has been a well-documented player in the prevention of tumors. It is considered the most frequently mutated gene in human tumors with more than half harboring p53 mutations (Bennett et al., 1999). These mutations often can be caused by disruption in normal p53 function.

11 Jun 2010

WaferGen announces microRNA, oncology gene panels for SmartChip Real-Time PCR System

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced the availability of two gene expression profiling panels for the SmartChip Real-Time PCR System that will enable microRNA and cancer pathway profiling capability.

10 Jun 2010

Caregiver's guide on avoiding life-threatening swallowing problems

That's the message of Drs. Roya Sayadi and Joel Herskowitz. They are a wife-husband team from Natick, Massachusetts, who are spreading the word that swallowing problems are everywhere - and they can be deadly!

10 Jun 2010

Study reveals insurance related differences in hospital mortality for AMI, stroke, pneumonia

An analysis of over 150,000 hospital discharges has revealed that there are significant insurance related differences in hospital mortality, length of stay, and costs among working-age Americans (age 18-64 years) hospitalized for acute myocardial infarction (AMI), stroke, or pneumonia. These three conditions are among the leading causes of non-cancer in-patient deaths in patients under 65 years old. The analysis is published today in the Journal of Hospital Medicine.

10 Jun 2010

Earlier school start times associated with increased teenage car crash rates: Research abstract

Earlier school start times are associated with increased teenage car crash rates, according to a research abstract that will be presented Wednesday, June 9, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

10 Jun 2010

Study: ChEI improves driving skills in patients with mild AD

A promising study from Rhode Island Hospital demonstrated that cholinesterase inhibitors, a type of medication often prescribed for Alzheimer's disease, improved some cognitive skills in patients with mild AD - skills that are necessary for driving. Findings from the study showed that after being treated with a ChEI, AD patients improved in some computerized tests of executive function and visual attention, including a simulated driving task.

10 Jun 2010

Medicalis launches Coordinated Imaging Care Solution

Medicalis Corporation announced today the launch of its Coordinated Imaging Care Solution (CICS), an integrated technology platform that provides clinical decision support, e-ordering, and extensive quality tracking that enables comparative effectiveness in medical imaging. The solution provides the broadest set of quality indicators specifically related to medical imaging available.

9 Jun 2010

Additional markers of risk for diabetic microvascular complications beyond Hemoglobin A1c needed

The "gold standard" diabetes test, Hemoglobin A1c (A1C), explains much less about the risk of cardiovascular complications in patients with diabetes than originally thought, according to an article in the June 9 issue of the Journal of the American Medical Association (JAMA). The article entitled, "Beyond HbA1c: Need for Additional Markers of Risk for Diabetic Microvascular Complications," was co-authored by Irl Hirsch, M.D., of the University of Washington Medical School (Seattle, WA) and Michael Brownlee, M.D., of the Albert Einstein College of Medicine.

9 Jun 2010

Research shows excessive daytime sleepiness increases depression symptoms among high school seniors

High school seniors with excessive daytime sleepiness have an elevated risk for depression, suggests a research abstract that will be presented Wednesday, June 9, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

9 Jun 2010

Clinical results from the use of hyperthermia to treat cervical cancer presented at ESHO meeting

BSD Medical Corporation today reported significant clinical results from the use of hyperthermia to treat cervical cancer. The results were presented at the annual meeting of the European Society for Hyperthermic Oncology, which was held in Rotterdam, The Netherlands, on May 19 to 21, 2010.

9 Jun 2010

Harvard and University of Montreal researchers challenge views on how cells respond to stimuli

People have them, cats have them and whales have some, too. Neurons, those interlinked nerve cells that carry sensations including pain, stretch from our spinal cords to the tips of our toes, paws or fins. According to a new study published in the journal Cell, scientists from the Harvard Medical School, the University of Montreal and the Dana-Farber Cancer Institute have found a new way by which nerve cells relay information that tell them to grow from millimeters to meters in length.

9 Jun 2010

$UC-MSCT improves symptoms, biochemical values in patients with severe refractory SLE: Study$

UC-MSCT improves symptoms, biochemical values in patients with severe refractory SLE: Study

A new study shows that umbilical cord mesenchymal stem cell transplant may improve symptoms and biochemical values in patients with severe refractory systemic lupus erythematosus.

8 Jun 2010

Research project to transform primary care practices into patient-centered medical homes concludes

An unprecedented research project into how to transform primary care practices into patient-centered medical homes has concluded with the release of a new eight-paper supplement to the May/June issue of Annals of Family Medicine.

8 Jun 2010

Medical School News and Research

Study confirms impact of febrile neutropenia on chemotherapy delivery in NHL

Discarded livers have potential to be reengineered into usable replacement organs: Researchers

Researchers identify 2,630 proteins that reside in human spinal fluid

Cook Medical files for PMA of Zilver PTX Drug-Eluting Peripheral Stent with FDA

Study on health disparities and sexual orientation

AVEO Pharmaceuticals presents tivozanib’s Phase 2 trial data at ASCO meeting

Study offers new insights into how brain chooses between behaviors that are critical for survival

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

WaferGen announces microRNA, oncology gene panels for SmartChip Real-Time PCR System

Caregiver's guide on avoiding life-threatening swallowing problems

Study reveals insurance related differences in hospital mortality for AMI, stroke, pneumonia

Earlier school start times associated with increased teenage car crash rates: Research abstract

Study: ChEI improves driving skills in patients with mild AD

Medicalis launches Coordinated Imaging Care Solution

Additional markers of risk for diabetic microvascular complications beyond Hemoglobin A1c needed

Research shows excessive daytime sleepiness increases depression symptoms among high school seniors

Clinical results from the use of hyperthermia to treat cervical cancer presented at ESHO meeting

Harvard and University of Montreal researchers challenge views on how cells respond to stimuli

UC-MSCT improves symptoms, biochemical values in patients with severe refractory SLE: Study

Research project to transform primary care practices into patient-centered medical homes concludes

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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