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Indero announces breakthrough method for early-phase evaluation of topical drugs using quantitative gene expression

Indero is proud to announce the successful completion of an internally funded study that introduces a novel approach to evaluating topical new chemical entities (NCE) in early-phase clinical research.

14 Nov 2025

Magnetic microrobots guide drugs directly to blood clots

Every year, 12 million people worldwide suffer a stroke; many die or are permanently impaired. Currently, drugs are administered to dissolve the thrombus that blocks the blood vessel.

14 Nov 2025

New study reveals how the uterus senses force to drive labor

When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver the baby safely.

13 Nov 2025

Off-label GLP-1 use highlights the cultural pressures driving body anxieties

New obesity drugs that were designed to treat diabetes and obesity are increasingly being used off-label by people without these conditions to achieve slimness and social approval rather than health gains. This perspective maps how such pharmacological thinness interacts with stigma, beauty ideals, digital culture, and inequality, and calls for multinational, intersectional research to understand its full impact.

13 Nov 2025

Modular magnetic microrobots achieve precision drug delivery

A magnetically guided microrobotics system is capable of navigating the body's intricate passageways and vasculature to deliver drugs with pinpoint accuracy, according to a new study.

13 Nov 2025

Cornell team unveils high-resolution tool for tracking kinase activity

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

13 Nov 2025

What The Health? From KFF Health News: The government is open

The longest federal government shutdown in history is over, after a handful of House and Senate Democrats joined most Republicans in approving legislation that funds the government through January. Despite Democrats' demands, the package did not include an extension of the expanded tax credits that help most Affordable Care Act enrollees afford their plans — meaning most people with ACA plans are slated to pay much more toward their premiums next year.

13 Nov 2025

Lymphoma resistance mechanisms and future therapies

A new review was published in Volume 12 of Oncoscience on October 13, 2025, titled "Targeted therapies and resistance mechanisms in lymphoma: Current landscape and emerging solutions."

13 Nov 2025

Pig kidney transplant breakthrough uncovers immune rejection secrets

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human.

13 Nov 2025

Scientists discover hidden weakness in Lyme disease bacterium

For decades, Lyme disease has frustrated both physicians and patients alike. Caused by the corkscrew-shaped bacterium Borrelia burgdorferi, the infection, if left untreated, can linger for months, leading to fever, fatigue and painful inflammation.

13 Nov 2025

Underweight children face higher risk of stopping ADHD medication early

Children who are underweight are more likely to stop taking their ADHD medication within a year. These are the findings of a study conducted at the University of Gothenburg on methylphenidate, a common pharmacological treatment in ADHD.

13 Nov 2025

Funding challenges threaten to reverse global gains in the fight against TB

Tuberculosis (TB) remains one of the world's deadliest infectious killers, claiming over 1.2 million lives and affecting an estimated 10.7 million people last year, according to the WHO Global Tuberculosis Report 2025, released today.

13 Nov 2025

ADHD symptoms linked to earlier substance use in young sexual minority men

Young sexual minority men – a term used to describe gay, bisexual, and other men who have sex with men – with attention-deficit/hyperactivity disorder (ADHD) symptoms are more likely to begin using substances such as cigarettes, alcohol, cannabis, stimulants and illicit drugs at an earlier age, according to Rutgers Health researchers.

13 Nov 2025

Cellarity's AI model predicts drug-induced liver injury

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.

13 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Collaborative effort advances next-generation therapies for pancreatic and GI cancers

Last year, researchers at the University of California, Riverside, developed a novel "molecular crowbar" strategy to degrade the oncogenic enzyme Pin1, a protein that is overexpressed in many tumors including pancreatic cancer.

12 Nov 2025

Rising youth e-cigarette use threatens children’s health and human rights

Exposing children to e-cigarettes compromises their human rights. These products should be regulated in a way that puts children's best interests first and protects them from the harms associated with nicotine consumption in all its forms, argue experts in The BMJ today.

12 Nov 2025

Extended use of anti-clotting drugs reduces risk of recurrent blood clots

Extending anti-clotting drugs beyond the initial treatment period of at least 90 days after a first blood clot is linked to lower rates of new clots developing compared with stopping treatment, finds a US study published by The BMJ today.

12 Nov 2025

New Mayo Clinic tool predicts Alzheimer’s risk years before symptoms begin

Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear.

12 Nov 2025

Single-dose malaria treatment using four drugs achieves high cure rates in clinical trial

Hundreds of malaria patients participating in a Phase 3 clinical trial in Gabon in West Africa were cured via a single dose of a treatment that utilizes four widely available malaria drugs, according to a new study presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

12 Nov 2025