Malignant News and Research

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Biologists analyze available methods of targeted drug delivery to malignant tumors

A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University analyzed available methods of targeted drug delivery to malignant tumors.

9 Apr 2019

Blood-based test for colon cancer shows promise, study finds

If caught early, nearly all cases of colon cancer are curable. Though this should make screening tests straightforward, colon cancer screening suffers from a paradoxical combination of low compliance rates and overdiagnosis.

9 Apr 2019

Cancer vaccine injected into tumour could kill all cancer cells

Researchers have developed an experimental cancer vaccine that when injected into a single tumour can help trigger the immune system to kill the cancer cells circulating within the body. The results of the study titled, “Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination,” were published in the latest issue of the journal Nature Medicine, this week, Monday.

9 Apr 2019

Children born via IVF more likely to develop cancer later in life

Scientists investigating have discovered a notable link between childhood cancer development and IVF.

3 Apr 2019

Protein discovery opens door for new options in diagnosis and therapy of cancer

Oncologists at the University and University Hospital in Tübingen have discovered a new protein variant that plays an important role in the development and therapy response of cancer.

3 Apr 2019

Research demonstrates clinical utility of ddPCR-powered liquid biopsy at 2019 AACR Annual Meeting

New research demonstrating the clinical utility of Bio-Rad's Droplet Digital PCR powered liquid biopsy will be presented this week during the 2019 American Association for Cancer Research Annual Meeting in Atlanta, March 29-April 3.

30 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found.

27 Mar 2019

BU researchers identify biomarker and possible new therapy for melanoma

Researchers have identified a biomarker and a possible new therapy for melanoma.

26 Mar 2019

Preclinical data shows combination immunotherapy could suppress tumor growth in the liver

Even as overall cancer incidence and mortality decrease in the United States, the number of people diagnosed with liver cancer is on the rise.

14 Mar 2019

Novel biosensor can isolate and target leukemic stem cells

All stem cells can multiply, proliferate and differentiate. Because of these qualities, leukemic stem cells are the most malignant of all leukemic cells. Understanding how leukemic stem cells are regulated has become an important area of cancer research.

12 Mar 2019

Bacteria from seawater provide new leads to treat malignant melanoma

Malignant melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. Now, researchers report in ACS Medicinal Chemistry Letters that a bacteria from seawater has inspired promising leads for an entirely new way to treat the disease.

7 Mar 2019

Artificial intelligence systems may detect breast cancer as accurately as radiologists

A new paper in the Journal of the National Cancer Institute suggests that artificial intelligence systems may be able to perform as accurately as radiologists in the evaluation of digital mammography in breast cancer screening.

6 Mar 2019

Research opens door to promising new treatment strategy for deadly brain tumor in children

A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma - the most deadly brain tumor in children.

4 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Protein content of tumors correlates with treatment response and survival in glioma patients

Brain tumors vary widely in how they respond to treatment. However, early assessment of therapy response is essential in order to choose the best possible treatment for the patient.

28 Feb 2019

Fusion of mitochondria enables cells to more efficiently use oxygen for energy

Mitochondria are the powerhouses of the cell. And for mitochondria, much like for double-header engines stacked together in a steam train, working in multiples has its benefits.

27 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Study shows link between ACA Medicaid expansion and impact of colon cancer on Kentuckians

A new University of Kentucky study published in the Journal of the American College of Surgeons shows a direct link between the adoption of the Affordable Care Act (ACA) Medicaid expansion and the impact of colon cancer on Kentuckians.

25 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

Malignant News and Research

Biologists analyze available methods of targeted drug delivery to malignant tumors

Blood-based test for colon cancer shows promise, study finds

Cancer vaccine injected into tumour could kill all cancer cells

Children born via IVF more likely to develop cancer later in life

Protein discovery opens door for new options in diagnosis and therapy of cancer

Research demonstrates clinical utility of ddPCR-powered liquid biopsy at 2019 AACR Annual Meeting

Cancer prevention drug also reduces virulence of H. pylori bacterium

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

BU researchers identify biomarker and possible new therapy for melanoma

Preclinical data shows combination immunotherapy could suppress tumor growth in the liver

Novel biosensor can isolate and target leukemic stem cells

Bacteria from seawater provide new leads to treat malignant melanoma

Artificial intelligence systems may detect breast cancer as accurately as radiologists

Research opens door to promising new treatment strategy for deadly brain tumor in children

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Protein content of tumors correlates with treatment response and survival in glioma patients

Fusion of mitochondria enables cells to more efficiently use oxygen for energy

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Study shows link between ACA Medicaid expansion and impact of colon cancer on Kentuckians

New study finds how high-fat diets fuel colorectal cancer growth

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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