RNA Sequencing News and Research

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Discovery of new liver cell could make liver transplants redundant

Researchers at King's College London have used single cell RNA sequencing to identify a type of cell that may be able to regenerate liver tissue, treating liver failure without the need for transplants.

26 Jul 2019

Researchers turn to single-cell analysis to understand a pediatric brain tumor

Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor.

25 Jul 2019

Rare inherited enzyme disorder offers new clues about fibrotic conditions

What can a family of rare inherited disorders teach scientists about more common health problems like fibrosis? Plenty, based on research led by St. Jude Children's Research Hospital scientists that appears today in the journal Science Advances.

17 Jul 2019

Comprehensive cell atlas of the human liver

The liver is one of the largest and most versatile organs of the human body. It turns sugars, proteins, and fats from our food into substances useful for the body and releases them to the cells.

11 Jul 2019

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma.

4 Jul 2019

Joslin researchers selected by Chan-Zuckerberg Initiative for Human Cell Atlas project

Researchers from Joslin Diabetes Center have been selected by the Chan-Zuckerberg Initiative as one of 38 collaborative science teams that will launch CZI's Seed Networks for a Human Cell Atlas projects.

29 Jun 2019

Comprehensive gene activity database could significantly reduce animal use

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which gives a full picture of the immune response to different pathogens.

29 Jun 2019

Cells in humans are affected by thirdhand smoke, study shows

Thirdhand smoke can damage epithelial cells in the respiratory system by stressing cells and causing them to fight for survival, a research team led by scientists at the University of California, Riverside, has found. The finding could assist physicians treating patients exposed to thirdhand smoke.

28 Jun 2019

Study finds new cancer driver which is fast, furious and loud

The Fast and the Furious movie franchise meets the Fast N' Loud television series to define an oncogene that drives 35% of prostate cancers.

27 Jun 2019

Scientists suggest possible cell-based therapy for premature infants with rare lung condition

Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia, which in the most severe cases can lead to lifelong breathing problems and even death.

27 Jun 2019

Study provides new insight into development of asthma

Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways.

27 Jun 2019

Researchers identify genes linked with survival in children with biliary atresia

Scientists at Cincinnati Children's Hospital Medical Center have identified an expression pattern of 14 genes at the time of diagnosis that predicts two year, transplant-free survival in children with biliary atresia – the most common diagnosis leading to liver transplants in children.

19 Jun 2019

Scientists unmask stem cell identity using gene-sequencing technology

Scientists from The University of Queensland's Diamantina Institute have revealed the difference between a stem cell and other blood vessel cells using gene-sequencing technology.

29 May 2019

New technique enables comprehensive genetic profiling of circulating tumor cells

A new way to cleanly separate out cancer cells from a blood sample enables comprehensive genetic profiling of the cancer cells, which could help doctors target tumors and monitor treatments more effectively.

16 May 2019

HSS researchers provide better understanding of the cellular mechanisms driving rheumatoid arthritis

Newly identified subsets of cell types present in joint tissue in people with rheumatoid arthritis and how they interact may explain why only some people respond to existing medications, according to two studies by co-senior author Laura Donlin, PhD, Co-Director of the Derfner Foundation Precision Medicine Laboratory at Hospital for Special Surgery and collaborating colleagues.

10 May 2019

RNA Sequencing News and Research

Discovery of new liver cell could make liver transplants redundant

Researchers turn to single-cell analysis to understand a pediatric brain tumor

Rare inherited enzyme disorder offers new clues about fibrotic conditions

Comprehensive cell atlas of the human liver

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Joslin researchers selected by Chan-Zuckerberg Initiative for Human Cell Atlas project

Comprehensive gene activity database could significantly reduce animal use

Cells in humans are affected by thirdhand smoke, study shows

Study finds new cancer driver which is fast, furious and loud

Scientists suggest possible cell-based therapy for premature infants with rare lung condition

Study provides new insight into development of asthma

Researchers identify genes linked with survival in children with biliary atresia

Scientists unmask stem cell identity using gene-sequencing technology

New technique enables comprehensive genetic profiling of circulating tumor cells

HSS researchers provide better understanding of the cellular mechanisms driving rheumatoid arthritis

Scientists decipher transcriptome of drumstick tree by RNA sequencing

Genomics study reveals five genes linked to treatment resistance in prostate cancer

Researchers create ‘mini-guts’ to explore how gut epithelium respond to gluten in celiac patients

Comprehensive brain map reveals ‘hidden’ microglia that may be involved in neurodegenerative diseases

MIT researchers develop novel method for analyzing massive cell datasets

Sequencing & Genomics: Elevating Science and Healthcare eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology