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Targeted Fab fragments dismantle the allergy trigger

Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such as anaphylaxis, asthma, food allergy, and allergic rhinitis are driven by immunoglobulin E (IgE), an antibody that binds to immune cells, including mast cells and basophils.

27 Jan 2026

Not all children with autism benefit from early language therapy

Understanding child profiles is crucial for improving language therapy in autism, as factors like cognitive abilities and imitation skills influence progress.

27 Jan 2026

Blood protein albumin identified as key defense against deadly black fungus

A new international study published in Nature has identified albumin, the most abundant protein in human blood, as a powerful and previously unrecognized defense against mucormycosis, a rare but often fatal fungal infection.

27 Jan 2026

Menopause associated with reduced brain volume and increased anxiety symptoms

Menopause is linked to reductions in grey matter volume in key brain regions as well as increased levels of anxiety and depression and difficulties with sleep, according to new research from the University of Cambridge.

27 Jan 2026

New prognostic model improves survival prediction for spinal metastasis patients

Spinal metastasis, the spread of cancer to the spine, is a frequent complication in advanced cancer. It often causes severe pain and paralysis, significantly impacting quality of life.

27 Jan 2026

WVU researchers explore how to restore vision in people with inherited blindness

A research team at the WVU is studying how to restore vision in people who develop a form of inherited blindness.

26 Jan 2026

Gene therapy targeting connexin 43 shows promise across inherited heart diseases

University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse model can dramatically improve heart function and extend survival in several inherited forms of arrhythmogenic cardiomyopathy (ACM)

26 Jan 2026

New trial tests strategies to protect heart health during prostate cancer therapy

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, has opened a phase 2 clinical trial comparing three different strategies for protecting heart health in prostate cancer patients who receive androgen deprivation therapy (ADT), a potentially lifesaving hormone therapy.

26 Jan 2026

Why exercise is essential for restoring fitness after GLP-1-based weight loss

This randomized controlled trial shows that structured moderate-to-vigorous exercise, alone or combined with liraglutide, improves physical function and cardiorespiratory fitness after diet-induced weight loss in adults with obesity. In contrast, liraglutide alone sustains weight loss but does not significantly improve measured physical fitness outcomes.

26 Jan 2026

New role for GLP-1 drugs: Improving survival in people with severe psychiatric disorders

This editorial argues that GLP-1 receptor agonists could substantially improve healthspan and reduce premature mortality in people with serious mental illnesses by targeting cardiometabolic risk rather than psychiatric symptoms alone. It highlights emerging evidence, safety considerations, and equity challenges that position GLP-1 RAs as a promising public health strategy for this high-risk population.

25 Jan 2026

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Familial Hypobetalipoproteinemia (FHBL), caused by variants in the apolipoprotein B (APOB) gene, is a rare autosomal co-dominant monogenic disorder characterized by lifelong low plasma levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and APOB.

24 Jan 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

New assessment framework improves evaluation of cutaneous chronic graft-versus-host disease

An international task force of medical experts recently proposed major revisions to the way doctors measure treatment success for a common–and often severe–skin complication of stem cell transplantation.

24 Jan 2026

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Metastatic urothelial carcinoma has a poor prognosis: ~50% of muscle-invasive bladder cancer progresses to metastasis, and the 5-year survival for advanced/metastatic disease is <10%.

24 Jan 2026

MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

23 Jan 2026

Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, they sometimes come with severe long-term consequences.

23 Jan 2026

Peptide-based platform marks a major step toward needle-free diabetes care

For more than a century, oral insulin has been considered a "dream" therapy for diabetes, hindered by enzymatic degradation in the digestive tract and the absence of a dedicated intestinal transport mechanism. Consequently, many patients must rely on daily insulin injections, which can significantly reduce their quality of life.

23 Jan 2026

New findings explain how lysosomal defects trigger neuronal energy failure

Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell type-specific atlas of lysosomes in the brain, the cell organelles which are responsible for degradation and recycling processes.

23 Jan 2026

Trojan horse immunotherapy opens tumors to immune system attack

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the cells that protect them.

22 Jan 2026

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Therapy News and Research

Targeted Fab fragments dismantle the allergy trigger

Not all children with autism benefit from early language therapy

Blood protein albumin identified as key defense against deadly black fungus

Menopause associated with reduced brain volume and increased anxiety symptoms

New prognostic model improves survival prediction for spinal metastasis patients

WVU researchers explore how to restore vision in people with inherited blindness

Gene therapy targeting connexin 43 shows promise across inherited heart diseases

New trial tests strategies to protect heart health during prostate cancer therapy

Why exercise is essential for restoring fitness after GLP-1-based weight loss

New role for GLP-1 drugs: Improving survival in people with severe psychiatric disorders

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Unraveling liver injury mechanisms in familial hypobetalipoproteinemia

Metabolic reprogramming drives prostate cancer progression and treatment resistance

New assessment framework improves evaluation of cutaneous chronic graft-versus-host disease

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors

Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes

Peptide-based platform marks a major step toward needle-free diabetes care

New findings explain how lysosomal defects trigger neuronal energy failure

Trojan horse immunotherapy opens tumors to immune system attack

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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