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Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

In a cancer that has not seen new targeted therapies for over 20 years, MUSC Hollings Cancer Center researcher and oncologist Nancy Klauber-DeMore, M.D., is pioneering new discoveries.

22 Jun 2021

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

A new class of drugs that inhibits a "master switch" involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

22 Jun 2021

MS symptoms often appear long before the diagnosis, study finds

Years before they are diagnosed, persons with multiple sclerosis (MS) make significantly more visits to doctors and hospitals than others.

22 Jun 2021

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor of physiology & biophysics and member of the Institute for Immunology at the University of California, Irvine.

22 Jun 2021

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

The most comprehensive molecular study to date of the brains of people who died of COVID-19 turned up unmistakable signs of inflammation and impaired brain circuits.

22 Jun 2021

Testing several genes can provide precise knowledge about the choice of right medicinal products

Most of us have genetic variations that increase the risk of medicinal products not being effective. In order to provide a more effective treatment with fewer side effects, we need to analyse more of these genetic variations.

22 Jun 2021

Combination of biological markers could improve triage and risk prediction in dengue patients

Researchers have identified a combination of biological markers in patients with dengue that could predict whether they go on to develop moderate to severe disease, according to a study published today in eLife.

22 Jun 2021

People with a history of childhood trauma get a more pleasurable 'high' from morphine

People who have experienced childhood trauma get a more pleasurable "high" from morphine, new research suggests.

22 Jun 2021

Mother's gestational diabetes is an independent risk factor for fetal hypoxia during labor

In Finland, every fifth mother was diagnosed with gestational diabetes in 2019. The condition increases the mother's risk of developing type 2 diabetes in the future.

22 Jun 2021

Family-based cancer clustering occurs more frequently among minority populations, study shows

Increased risk of cancer due to a genetic predisposition in first- and second-degree relatives is long-established but has previously only been studied in white or European populations.

22 Jun 2021

In a murky sea of mental health apps, consumers left adrift

In the eyes of the tech industry, mental health treatment is an area ripe for disruption.

22 Jun 2021

Hospitals, insurers invest big dollars to tackle patients’ social needs

When doctors at a primary care clinic here noticed many of its poorest patients were failing to show up for appointments, they hoped giving out free rides would help.

22 Jun 2021

Smoother silicone breast implants can reduce inflammation and other immune system reactions

According to researchers at Johns Hopkins Medicine, the Massachusetts Institute of Technology (MIT) and Rice University in Houston, silicone breast implants with a smoother surface design have less risk of producing inflammation and other immune system reactions than those with more roughly textured coatings.

22 Jun 2021

RedHill presents positive Phase 2 results for oral opaganib in patients with COVID-19 pneumonia

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced presentation of the positive Phase 2 safety and efficacy data for oral opaganib (Yeliva®, ABC294640) in hospitalized patients with COVID-19 pneumonia at the World Microbe Forum (WMF) 2021 (poster #: 5574).

21 Jun 2021

Study identifies significant inequalities in the Liverpool 'mass testing' pilot

A study by the University of Liverpool has shown that while asymptomatic COVID-19 testing in Liverpool was popular, significant inequalities were evident between those who got tested and those who didn't.

21 Jun 2021

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

A team led by researchers at Newcastle University, UK has successfully created a model of the cells found in the lungs that can be used to replicate how COVID-19 infects the airways.

21 Jun 2021

Researchers analyze how breast implant surfaces influence immune response

Rice University bioengineers collaborated on a six-year study that systematically analyzed how the surface architecture of breast implants influences the development of adverse effects, including an unusual type of lymphoma.

21 Jun 2021

Training stroke survivors to walk at a faster speed improves dual-task performance

Research has found that training stroke survivors to walk at a faster speed during recovery can help improve the brain function that enables people to walk and perform another task simultaneously, known as dual-task walking.

21 Jun 2021

New breakthrough could lead to a cure for common childhood cancer

Scientists studying a common childhood cancer have made a major breakthrough which could lead to a cure for some youngsters who would not have survived the condition.

21 Jun 2021

Study details health risks, growth patterns, and treatment outcomes of people with achondroplasia

In a retrospective study believed to be one of the largest of its kind, researchers say they have successfully charted the health risks, growth patterns, and medical and surgical outcomes of 1,374 people with the most common form of dwarfism, called achondroplasia, seen over a 60-year period at four academic medical centers, including Johns Hopkins Medicine.

21 Jun 2021

Hospital News and Research

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

MS symptoms often appear long before the diagnosis, study finds

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

Testing several genes can provide precise knowledge about the choice of right medicinal products

Combination of biological markers could improve triage and risk prediction in dengue patients

People with a history of childhood trauma get a more pleasurable 'high' from morphine

Mother's gestational diabetes is an independent risk factor for fetal hypoxia during labor

Family-based cancer clustering occurs more frequently among minority populations, study shows

In a murky sea of mental health apps, consumers left adrift

Hospitals, insurers invest big dollars to tackle patients’ social needs

Smoother silicone breast implants can reduce inflammation and other immune system reactions

RedHill presents positive Phase 2 results for oral opaganib in patients with COVID-19 pneumonia

Study identifies significant inequalities in the Liverpool 'mass testing' pilot

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

Researchers analyze how breast implant surfaces influence immune response

Training stroke survivors to walk at a faster speed improves dual-task performance

New breakthrough could lead to a cure for common childhood cancer

Study details health risks, growth patterns, and treatment outcomes of people with achondroplasia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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