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A mucoadhesive polymer with anti-SARS-COV-2 activity in vitro and in vivo

The team has evaluated a low molecular weight chitosan derivative as a candidate preventing the viral entry into mammalian nasal epithelial cells to limit the spread of COVID-19.

12 Oct 2021

Taste loss as a COVID-19 symptom: a review

A new review reports that alterations in taste affected about a third of individuals with a COVID-19 diagnosis, with females being affected more than males.

12 Oct 2021

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

A recent preprint discusses the antibody response to the nucleic acid vaccines against SARS-CoV-2 when administered to children aged 7-11 years.

12 Oct 2021

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

A new paper shows that human TLR3, TLR7, and TLR8 receptors are activated with naturally occurring RNA, but this is eliminated once modified nucleosides such as m5C, m6A, m5U s2U, or pseudouridine are incorporated.

12 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

Study uncovers mechanism that may underlie greater sensitivity of certain skin regions

Some parts of the body - our hands and lips, for example - are more sensitive than others, making them essential tools in our ability to discern the most intricate details of the world around us.

11 Oct 2021

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

Oncotarget published "Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing" which reported that the adequate functioning of this process is indispensable for tissue homeostasis and cell fate determination.

11 Oct 2021

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Scientists at Washington University School of Medicine in St. Louis have developed a compound that prevents SARS-CoV-2 and related coronaviruses from entering cells.

11 Oct 2021

Penn Medicine's new Pavilion is set to open this month to staff, patients, and visitors

Referred to as a "Beacon of Hope," Penn Medicine's new Pavilion, one of the largest hospital projects underway in the United States, opens to staff, patients, and visitors this month.

11 Oct 2021

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

11 Oct 2021

New algorithm provides a high-definition analysis of genome organization in single cells

Within the microscopic boundaries of a single human cell, the intricate folds and arrangements of protein and DNA bundles dictate a person's fate: which genes are expressed, which are suppressed, and - importantly - whether they stay healthy or develop disease.

11 Oct 2021

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

A new study assesses antibody and functional T-cell responses at 6 months after complete vaccination with the Pfizer-BioNTech vaccine.

11 Oct 2021

Mushroom consumption may benefit a person's mental health

Mushrooms have been making headlines due to their many health advantages. Not only do they lower one's risk of cancer and premature death, but new research led by Penn State College of Medicine also reveals that these superfoods may benefit a person's mental health.

11 Oct 2021

New molecular understanding of variations in salmonella virulence

Researchers from the University of Seville, in collaboration with the universities of Zaragoza and Kansas (USA), have managed to describe hitherto unknown processes that allow us to understand the virulence of a Salmonella infection.

11 Oct 2021

Antibody validation and rapid peptide mapping technology

In this interview, News-Medical speaks to Bin Ma, President of Rapid Novor, about antibody validation and rapid peptide mapping technology.

From Rapid Novor Inc 11 Oct 2021

Researchers discover molecules in the blood that can indicate impending dementia

Researchers at the DZNE and the University Medical Center Göttingen (UMG) have identified molecules in the blood that can indicate impending dementia. Their findings, which are presented in the scientific journal "EMBO Molecular Medicine", are based on human studies and laboratory experiments. Various university hospitals across Germany were also involved in the investigations.

11 Oct 2021

B Cell News and Research

A mucoadhesive polymer with anti-SARS-COV-2 activity in vitro and in vivo

Taste loss as a COVID-19 symptom: a review

Vaccinated children induced significantly higher antibody titers than naturally SARS-CoV-2 infected children

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

Research reveals components of Sinbis virus ribonucleoproteins

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Study uncovers mechanism that may underlie greater sensitivity of certain skin regions

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

New compound can prevent SARS-CoV-2 and related coronaviruses from entering cells

Penn Medicine's new Pavilion is set to open this month to staff, patients, and visitors

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

New algorithm provides a high-definition analysis of genome organization in single cells

SARS-CoV-2 immune responses in nursing home residents after full vaccination with Pfizer-BioNTech COVID-19 vaccine

Mushroom consumption may benefit a person's mental health

New molecular understanding of variations in salmonella virulence

Antibody validation and rapid peptide mapping technology

Researchers discover molecules in the blood that can indicate impending dementia

The role of inhibiting palmitoylation of the SARS-CoV-2 spike protein on viral infectivity

Delta variant exhibits immune evasion, enhanced cell entry, and augmented syncytium formation

Vaccine-induced memory B cells can recognize SARS-CoV-2 variants

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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