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TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

Pain impacts nearly every individual at some point in their lives. With more than 25 million adults in the U.S. experiencing daily pain, the U.S. is facing a crisis due to the high prevalence of chronic pain and associated opioid use disorder and overdose deaths.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Study on sea sponge opens up possibilities to create new antitumor drugs

Chemists from Far Eastern Federal University's School of Natural Sciences developed a new method to synthesize biologically active derivatives of fascaplysin -- cytotoxic pigment of a sea sponge. For the first time, they got a sufficient amount of 3-bromofascaplysin and 3,10-dibromofascaplysin, which were known before but were not available for study.

14 Nov 2019

New computational model could help in the development of anti-cancer drugs

Researchers from the Faculty of Medicine and the Institute for Molecular Medicine at the University of Helsinki have developed a computational model, Combined Essentiality Scoring (CES) that enables accurate identification of essential genes in cancer cells for development of anti-cancer drugs.

14 Nov 2019

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

After decades of little or no progress, biomedical researchers are finally making some headway at detecting and treating sepsis, a deadly medical complication that sends a surge of pathogenic infection through the body and remains a major public health problem.

14 Nov 2019

Blocking a molecule could delay the progression of multiple sclerosis

Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure.

14 Nov 2019

New technique enables the study of transporter proteins at a single-molecule level

Like a boat helping passengers cross a river, transporters move substances across cell membranes. This process is fundamental to the healthy functioning of cells in life forms from bacteria to humans.

14 Nov 2019

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according to a study published in Nature Communications today.

14 Nov 2019

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Turbine, a simulation-based drug discovery company today announced the closing of an institutional financing round led by Delin Ventures.

From Turbine Simulated Cell Technologies Ltd. 14 Nov 2019

Tips to help parents share family health history with children

Parents spend hours planning to talk with their children about the "birds and bees." But moms and dads often ignore an equally important conversation - discussing their family's overall health history.

13 Nov 2019

Regular co-use of pain and sleep medications may increase risk of frailty in older adults

Researchers from the Oregon Research Institute and Florida Atlantic University are the first to demonstrate statistically significant links between self-reported regular use of prescription drugs for pain and/or sleep, and longitudinal risk of frailty in adults ages 65 and older.

13 Nov 2019

Deterministic mechanoporation of cells en masse to cure cancer

What if you could cure cancer by re-engineering patients' cells to better target and destroy their own tumors? With the advent of powerful new cellular engineering technologies, this is no longer the stuff of science fiction.

13 Nov 2019

Pacemaker-like device improves heart function in patients with chemotherapy-induced cardiomyopathy

With the advent of new therapies, cancer patients are surviving longer than ever before -- but the incidence of side-effect chemotherapy-induced cardiomyopathy (CHIC), or weakness of the heart muscle, is increasing.

13 Nov 2019

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

13 Nov 2019

Deep neural network could improve cancer care

Improving the detection, diagnosis, and treatment of diseases like cancer will require more detailed, rapid, and agile imaging technology that can show doctors not just what a specific organ looks like, but also what's happening within the cells that make up those tissues.

13 Nov 2019

$Receiving multiple fracture-associated drugs may increase hip fracture risk$

Receiving multiple fracture-associated drugs may increase hip fracture risk

There is a strong association between the number of fracture-associated drugs (FADs) older patients receive and their risk of sustaining a broken bone, according to a new Dartmouth study published in JAMA Network Open.

13 Nov 2019

Researchers develop novel mathematical framework for mapping out drug interaction

Combining two or more drugs can be an effective treatment of diverse diseases, such as cancer. Yet, at the same time, the wrong drug combination can cause major side effects. Currently there is no systematic understanding of how different drugs influence each other. Thus, elucidating how two given drugs interact, and whether they have a beneficial effect, would mean a major step towards drug development to treat diseases more effectively in the future.

13 Nov 2019

'Smart toilets' may work as real-time method of monitoring health

Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity - the humble toilet - may have potential to outperform them all.

13 Nov 2019

Leukemia type B cell can transform into a macrophage through epigenetic changes

All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects.

13 Nov 2019

Kratom may be effective, but not entirely safe to treat alcohol use disorder

Lawmakers across the United States continue to debate the safety of kratom, an opioid-containing plant that has been listed as a "drug of concern" by the U.S. Food and Drug Administration. Kratom is sold over the counter in specialty stores and online.

13 Nov 2019

Drugs News and Research

TACC announces role as key collaborator in NIH grant to study chronic pain and opioid dependence

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Study on sea sponge opens up possibilities to create new antitumor drugs

New computational model could help in the development of anti-cancer drugs

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

Blocking a molecule could delay the progression of multiple sclerosis

New technique enables the study of transporter proteins at a single-molecule level

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

Turbine secures institutional financing of €3m to expand potential of simulation-first drug discovery

Tips to help parents share family health history with children

Regular co-use of pain and sleep medications may increase risk of frailty in older adults

Deterministic mechanoporation of cells en masse to cure cancer

Pacemaker-like device improves heart function in patients with chemotherapy-induced cardiomyopathy

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Deep neural network could improve cancer care

Receiving multiple fracture-associated drugs may increase hip fracture risk

Researchers develop novel mathematical framework for mapping out drug interaction

'Smart toilets' may work as real-time method of monitoring health

Leukemia type B cell can transform into a macrophage through epigenetic changes

Kratom may be effective, but not entirely safe to treat alcohol use disorder

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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