Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Single protein could be a new target for delaying onset of aging symptoms in the brain

It is not every day that scientists come across a phenomenon so fundamental that it is observed across fruit flies, rodents and humans.

29 Apr 2021

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Experimental Alzheimer's drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations.

29 Apr 2021

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Researchers at University of California San Diego School of Medicine have discovered one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

29 Apr 2021

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

A Ludwig Cancer Research study has identified a previously unrecognized mechanism by which cancer cells of a relatively benign subtype of pancreatic tumors methodically revert-or "de-differentiate"-to a progenitor, or immature, state of cellular development to spawn highly aggressive tumors that are capable of metastasis to the liver and lymph nodes.

29 Apr 2021

New insights into how South African SARS-CoV-2 variant sacrifices tight binding for antibody evasion

The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection.

29 Apr 2021

Algorithm interprets data from electronic medical records to diagnose kidney disease

Diagnosing chronic kidney disease, which is often undetected until it causes irreversible damage, may soon become automated with a new algorithm that interprets data from electronic medical records.

29 Apr 2021

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer.

29 Apr 2021

Researchers propose a new universal nomenclature for vasotocin and oxytocin genes

Oxytocin and arginine vasopressin are two hormones in the endocrine system that can act as neurotransmitters and regulate -in vertebrates and invertebrates- a wide range of biological functions, such as bonding formation, breastfeeding, birth or arterial pressure.

29 Apr 2021

Potent monoclonal antibody shows promise against emerging SARS-CoV-2 variants of concern

In a new study currently available on the bioRxiv* preprint server, a group of US-based researchers developed a panel of neutralizing monoclonal antibodies against SARS-CoV-2 that can block viral attachment to cells – and pinpointed a specific one that can potently neutralize all tested variants of concern.

28 Apr 2021

Researchers investigate how the brain's circadian rhythm control center regulates behavior

Our bodies and behaviors often seem to have rhythms of their own. Why do we go to the bathroom at the same time every day? Why do we feel off if we can't go to sleep at the right time? Circadian rhythms are a behind-the-scenes force that shape many of our behaviors and our health.

28 Apr 2021

New model may explain the perplexing asymmetrical motor symptoms in Parkinson's disease

Parkinson's disease (PD) is characterized by slowness of movement and tremors, which often appear asymmetrically in patients.

28 Apr 2021

New method could be used to develop more effective treatments for cancer, metabolic disorders

Researchers from the University of Copenhagen have developed a new method that makes it possible to control human hormones and metabolism.

28 Apr 2021

Recovered COVID-19 patients show signs of long-term immunity

A study conducted by researchers in the United States has found that most patients who recovered from coronavirus disease 2019 (COVID-19) showed signs of long-lasting immunity against the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Apr 2021

Brazilian coronavirus variant could pose a bigger threat than previously assumed

A new study with the University of Copenhagen represented indicates that the coronavirus variant called P.1, which originated in Brazil, could pose a bigger threat than previously assumed.

28 Apr 2021

Nanobodies may be the key to blocking tick-borne bacterial infection

Tiny molecules called nanobodies, which can be designed to mimic antibody structures and functions, may be the key to blocking a tick-borne bacterial infection that remains out of reach of almost all antibiotics, new research suggests.

28 Apr 2021

COVID-19 donor antibodies show broad cross-reactivity against SARS-CoV-2 variants and related viruses

A new study reports on a set of antibodies from COVID-19 donor serum, which seems to be cross-reactive across multiple Sarbecoviruses, including the very similar SARS-CoV-2, SARS-CoV and Middle East Respiratory Syndrome (MERS)-CoV.

28 Apr 2021

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

A new study describes a synthetic peptide used as a platform to generate protective adaptive cellular immunity to the virus in rhesus macaques, which are the gold standard for preclinical testing in humans.

28 Apr 2021

SARS-CoV-2 recruits heme metabolites in antibody evasion

A research paper recently published in the journal Science Advances by Cherepanov et al. (April 22nd, 2021) demonstrated that the NTD binds to biliverdin, a product of heme catabolism, leading to enhanced antibody escape at physiologically relevant concentrations.

28 Apr 2021

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

New research led by Hana El-Samad of the University of California, San Francisco, and the Chan-Zuckerberg Biohub confirmed the beneficial use of an antiviral therapeutic called SARSNotch, which uses a combination of the SynNotch platform and de-novo designed protein binders. SARSNotch uses sentinel T cells to detect and mount a genetic response toward the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

28 Apr 2021

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Scientific studies rarely focus on long non-coding RNA molecules (lncRNAs), even though they potentially regulate several diseases. The role of several lncRNAs in anti-viral inflammatory response regulation has recently been reported.

28 Apr 2021

Protein News and Research

Further Reading

Single protein could be a new target for delaying onset of aging symptoms in the brain

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

New insights into how South African SARS-CoV-2 variant sacrifices tight binding for antibody evasion

Algorithm interprets data from electronic medical records to diagnose kidney disease

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

Researchers propose a new universal nomenclature for vasotocin and oxytocin genes

Potent monoclonal antibody shows promise against emerging SARS-CoV-2 variants of concern

Researchers investigate how the brain's circadian rhythm control center regulates behavior

New model may explain the perplexing asymmetrical motor symptoms in Parkinson's disease

New method could be used to develop more effective treatments for cancer, metabolic disorders

Recovered COVID-19 patients show signs of long-term immunity

Brazilian coronavirus variant could pose a bigger threat than previously assumed

Nanobodies may be the key to blocking tick-borne bacterial infection

COVID-19 donor antibodies show broad cross-reactivity against SARS-CoV-2 variants and related viruses

Peptide nucleocapsid vaccine candidate elicits protective T cell immunity against SARS-CoV-2 in vivo

SARS-CoV-2 recruits heme metabolites in antibody evasion

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

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