Cell Line News and Research

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Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Scientists produce functioning neurons from human embryonic stem cells

Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer's, Parkinson's, prefrontal dementia and schizophrenia.

8 Aug 2007

Discredited Korean embryonic stem cells' true origins revealed

A report from researchers at Children's Hospital Boston and the Harvard Stem Cell Institute sheds new light on a now-discredited Korean embryonic stem cell line, setting the historical record straight and also establishing a much-needed set of standards for characterizing human embryonic stem cells.

3 Aug 2007

Stem cell therapy rescues motor neurons in ALS model

In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease.

3 Aug 2007

Neuroprotectin D1 protects retinal pigment epithelial (RPE) cells

Two papers to be published in the Early Edition online of the Proceedings of the National Academy of Sciences (PNAS) the week of July 30-August 3, 2007 report findings that demonstrate that neuroprotectin D1 (NPD1) protects against damage to retinal pigment epithelial (RPE) cells and identifies an important trigger for its production and novel molecular mechanisms that support vision.

1 Aug 2007

Stem cell therapy rescues motor neurons in amyotrophic lateral sclerosis model

31 Jul 2007

New algorithm matches any tumor cells to best possible anti-cancer treatments

Cancer patients don't have time to waste. Many go through several different treatments, however, to find one that is more effective against their particular type of tumor.

24 Jul 2007

Abiogen licenses RFB4 antibody from Cancer Research Technology

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, today announces it has agreed an exclusive worldwide licence with Abiogen Pharma S.p.A. (Italy).

11 Jul 2007

Olive-pomace oil slows down AIDS

Olive oil has become part of the fight against the Human Immunodeficiency Virus (HIV) - the cause of AIDS - thanks to the research carried out by the Bionat team, from the University of Granada, headed by Prof. Andres Garcia-Granados, senior lecturer in Organic Chemistry.

9 Jul 2007

Human immune system in a test tube

Surgical instruments or implants that are contaminated with residual bacteria, or pyrogens, can cause blood poisoning in patients. Researchers are developing a test that imitates the human immune system in the laboratory, eliminating the need for animal experiments.

4 Jul 2007

Why NSAIDs damage the tissue that lines the gastrointestinal tract

New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine.

23 Jun 2007

New understanding of how the DNA helix replicates

A team of researchers led by University of Virginia Health System geneticists has uncovered a major secret in the mystery of how the DNA helix replicates itself time after time.

18 Jun 2007

Noninvasive treatment of cancer tumors

Ram Devireddy, assistant professor of mechanical engineering at LSU, recently co-authored an article with Todd Monroe, assistant professor of biological and agricultural engineering, investigating the complex effects of nanoparticles on cell freezing.

18 Jun 2007

A single cancer stem cell is sufficient to initiate and maintain a malignant tumor

At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line , established long ago , turned out to behave a lot like cancer stem cells.

14 Jun 2007

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in mice

Rats with erectile dysfunction, or ED, that were injected with a gene therapy vector containing either of two nerve growth factors were able to regain normal function after four weeks, according to a study conducted by University of Pittsburgh School of Medicine researchers.

5 Jun 2007

Researchers explore the glycosylation process

By studying the addition of sugars to proteins — a process called glycosylation — in the nervous system of insects, Temple University researcher Karen Palter believes she may be able to better understand neurodegenerative diseases in humans.

28 May 2007

New mechanism identified for resistance to targeted lung cancer drugs

An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva.

27 Apr 2007