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Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

After ‘a lot of doors shut in our face,’ crusading couple celebrate passage of burn pit bill

The battle was just beginning for Le Roy Torres and his wife, Rosie, when the Army captain returned to Texas in 2008, already starting to suffer from the toxic substances he'd inhaled from the 10-acre burn pit at Camp Anaconda in Balad, Iraq.

9 Aug 2022

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

A recent paper describes the use of aprotinin, a protease inhibitor that works across several pathways, to reduce the severity of COVID-19.

8 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio 3 Aug 2022

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

A recent study published in the Journal of Food Biochemistry discovered that peimine from Fritillaria might be a possible SARS-CoV-2 variant infection inhibitor.

2 Aug 2022

The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

Researchers evaluated the efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell cultures.

2 Aug 2022

What is the safety of Molnupiravir against SARS-CoV-2 in the elderly?

A new study assessed the safety of the oral administration of Molnupiravir to elderly patients––aged 80 or older, hospitalized with COVID-19.

1 Aug 2022

Lower levels of dietary calcium and potassium predict recurrence of kidney stones

Kidney stones can cause not only excruciating pain but also are associated with chronic kidney disease, osteoporosis and cardiovascular disease. If you've experienced a kidney stone once, you have a 30% chance of having another kidney stone within five years.

1 Aug 2022

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

A new study reports the activity of a compound which inhibited TMPRSS2, ultimately preventing severe COVID-19.

28 Jul 2022

Novel targeted therapy may be an effective treatment option for neuroblastoma

New research from VCU Massey Cancer Center - published Thursday in Cell Reports - demonstrated that a novel targeted therapy could be an effective treatment option for a deadly pediatric cancer known as neuroblastoma.

28 Jul 2022

Repurposing an antipsychotic drug to treat various types of cancer

To treat some of the psychosis issues associated with Parkinson's disease, physicians often prescribe pimavanserin, an antipsychotic drug that acts within the brain to prevent hallucinations and delusions.

28 Jul 2022

GenTech Scientific and Conquer Scientific join forces and become allies in analytical instrumentation and services

As allies, the GenTech and Conquer union creates a global force, offering a robust service network with unmatched resources and an unparalleled inventory of refurbished analytical instruments. LabX caught up with Yvette Pagano, Chief Commercial Officer at GenTech to discuss the acquisition and the current and future plans for this combined powerhouse.

From GenTech Scientific 28 Jul 2022

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

When all else fails, some patients trying to overcome alcoholism, severe depression or anxiety, and even cluster headaches, turn to psychedelic drugs, which clinical research has shown can help treat individuals with these conditions, sometimes with dramatically positive results.

27 Jul 2022

Compound News and Research

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

After ‘a lot of doors shut in our face,’ crusading couple celebrate passage of burn pit bill

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

What is the safety of Molnupiravir against SARS-CoV-2 in the elderly?

Lower levels of dietary calcium and potassium predict recurrence of kidney stones

TMPRSS2 protein, a novel target for SARS-CoV-2 drugs

Novel targeted therapy may be an effective treatment option for neuroblastoma

Repurposing an antipsychotic drug to treat various types of cancer

GenTech Scientific and Conquer Scientific join forces and become allies in analytical instrumentation and services

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

New method could lead to more efficient production of next-generation antibiotics

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Genetic variations in serotonin receptor causes different response to psychedelic drugs

Cocoa reduces blood pressure and arterial stiffness, study finds

Research may have found an easy, cost-effective solution for Grapevine Trunk Diseases

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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