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Single-cell analysis illuminates myeloma immune landscape

Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients with multiple myeloma, a blood cancer that, while treatable, remains incurable.

9 Jan 2026

Non-coding RNA mutations unveiled as new cause of retinitis pigmentosa

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with night blindness in youth and progresses to tunnel vision as daylight-sensing photoreceptor cells in the retina gradually die, potentially leading to blindness over time.

9 Jan 2026

Immune cell atlas may improve survival predictions, guide treatment decisions in multiple myeloma

aps the immune cell landscape of bone marrow in patients with multiple myeloma, a rare cancer that develops in the plasma cells of the bone marrow and has no cure.

9 Jan 2026

APOE gene: A major driver in Alzheimer's disease

Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers.

9 Jan 2026

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

Bacterial communities in colorectal cancer reveal patterns linked to tumor genetics and patient outcomes, paving the way for personalized treatment strategies.

From BGI Genomics 9 Jan 2026

New method measures how effectively antibiotics kill bacteria

Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions.

9 Jan 2026

Study reveals innate immune barriers to long-term pig kidney transplant survival

Pioneering research led by Brazilians describes the immune system's reactions in detail in the first living patient to receive a genetically modified pig kidney transplant.

8 Jan 2026

Giant amoeba-infecting viruses offer new clues to the origin of eukaryotic life

The origin of life on Earth becomes even more fascinating and complex as we peer into the mysterious world of viruses.

8 Jan 2026

Unveiling IDH-mutant glioma's roots: A new path for early diagnosis

IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50.

8 Jan 2026

Scientists discover how stem cells navigate and repair brain damage after stroke

Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of the eye-called the cornea-can heal from minor scratches within a single day.

8 Jan 2026

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called clonal hematopoiesis of indeterminate potential (CHIP).

8 Jan 2026

CIRM awards $7.4 million to advance stem cell-based gene therapy for Friedreich's ataxia

The California Institute for Regenerative Medicine (CIRM) has awarded $7.4 million to support a University of California San Diego team developing a first-of-its-kind stem cell-based gene therapy for Friedreich's ataxia, a rare inherited neurodegenerative disease that causes progressive loss of coordination, muscle strength, heart function and overall mobility.

8 Jan 2026

"Super-probiotic" bacteria created through ribosomal engineering

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG).

8 Jan 2026

Dual pathways found for centromere specification, ensuring accurate chromosome segregation

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

8 Jan 2026

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

The study reveals that environmental stressors do not merely kill bacteria; they can also prime surviving cells to take up resistance genes more efficiently, raising concerns about how antibiotic-resistant bacteria may spread in aquatic environments.

8 Jan 2026

Why promising microbiome therapies rarely work in patients

Addressing the microbiome's translational gap involves understanding biological complexity and developing function-driven, patient-specific interventions.

8 Jan 2026

New DNA tests reveal hidden biological traces on Renaissance art

DNA analysis of cultural artifacts shows diverse biological profiles, but contamination and mixed signals complicate historical lineage interpretation.

8 Jan 2026

New partnership launches marketplace to revive deprioritized cell and gene therapies

The American Society of Gene & Cell Therapy (ASGCT), the leading professional organization for the advancement of cell and gene therapies (CGTs), and the Orphan Therapeutics Accelerator (OTXL), a non-profit biotech focused on completing development and enabling access to stalled rare disease treatments, today announced a partnership to establish CGTxchange, a jointly owned entity that will serve as a clearinghouse and marketplace for deprioritized CGTs.

7 Jan 2026

BATF2: A novel tumor suppressor silenced by glutamine in head and neck cancer

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

7 Jan 2026

Brazilian study shows liquid biopsies can expedite lung cancer care

In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for expediting diagnoses and guiding patient treatment.

7 Jan 2026

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Genetic News and Research

Single-cell analysis illuminates myeloma immune landscape

Non-coding RNA mutations unveiled as new cause of retinitis pigmentosa

Immune cell atlas may improve survival predictions, guide treatment decisions in multiple myeloma

APOE gene: A major driver in Alzheimer's disease

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

New method measures how effectively antibiotics kill bacteria

Study reveals innate immune barriers to long-term pig kidney transplant survival

Giant amoeba-infecting viruses offer new clues to the origin of eukaryotic life

Unveiling IDH-mutant glioma's roots: A new path for early diagnosis

Scientists discover how stem cells navigate and repair brain damage after stroke

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

CIRM awards $7.4 million to advance stem cell-based gene therapy for Friedreich's ataxia

"Super-probiotic" bacteria created through ribosomal engineering

Dual pathways found for centromere specification, ensuring accurate chromosome segregation

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

Why promising microbiome therapies rarely work in patients

New DNA tests reveal hidden biological traces on Renaissance art

New partnership launches marketplace to revive deprioritized cell and gene therapies

BATF2: A novel tumor suppressor silenced by glutamine in head and neck cancer

Brazilian study shows liquid biopsies can expedite lung cancer care

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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