OCT News and Research

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Study links long COVID to gut inflammation and serotonin deficiency

Patients with long COVID – the long-term symptoms like brain fog, fatigue, or memory loss in the months or years following COVID-19 – can exhibit a reduction in circulating levels of the neurotransmitter serotonin, according to new research published today in Cell.

16 Oct 2023

Study shows outsized toll of dementia on family caregivers and finances

Most people think of dementia as something that affects a person's brain. But a new study shows just how much damage it does to a person's wallet and bank account too – as well as the higher demands it places on their family members.

16 Oct 2023

Study reveals previously unappreciated role for innate immune cells in early stages of TB infection

A new study from the University of Pittsburgh Center for Vaccine Research published today in the Journal of Experimental Medicine describes a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.

16 Oct 2023

Two 'big gun' antibiotics may be safer for the kidneys than previously thought

Two 'big gun' antibiotics thought to cause kidney failure in ICU patients with a severe bacterial infection, especially when combined with another antibiotic, may be safer for the kidneys than previously reported, following a randomized trial led by Vanderbilt University Medical Center.

16 Oct 2023

Study highlights need for early intervention for behavioral problems

A six-year study that analyzed data from a 25-question screening tool found alarming evidence of unhealthy behavioral trajectories starting as early as age 2 among families affected by low income and other social stressors.

16 Oct 2023

Moffitt Cancer Center researchers identify hidden target of ROS1 inhibitor lorlatinib

Targeted cancer drugs are widely used because of their ability to inhibit specific proteins involved in cancer development with fewer side effects compared to chemotherapy drugs.

16 Oct 2023

Live vaccinations found to be safe for pediatric organ transplant recipients

Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions, according to a new study published Oct. 12, 2023, in JAMA Network Open.

16 Oct 2023

Medicare enrollees can switch coverage now. Here’s what’s new and what to consider.

Consumers know it's fall when stores start offering Halloween candy and flu shots — and airwaves and mailboxes are filled with advertisements for Medicare options.

16 Oct 2023

Doctors abandon a diagnosis used to justify police custody deaths. It might live on, anyway.

Brooks Walsh hadn't questioned whether "excited delirium syndrome" was a legitimate medical diagnosis before the high-profile police killings of Elijah McClain in Colorado in 2019 and George Floyd in Minnesota in 2020.

16 Oct 2023

Study identifies significant percentage of ventilated patients colonized with life-threatening pathogens

University of Maryland School of Medicine (UMSOM) researchers conducted a statewide survey of all patients on breathing machines in hospitals and long-term care facilities and found that a significant percentage of them harbored two pathogens known to be life-threatening in those with compromised immune systems.

13 Oct 2023

New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

13 Oct 2023

Calorie restriction may rejuvenate muscles and activate biological pathways for healthy aging

Reducing overall calorie intake may rejuvenate your muscles and activate biological pathways important for good health, according to researchers at the National Institutes of Health and their colleagues.

13 Oct 2023

University of Kentucky selected as the nationwide coordination center for NIH racial equity initiative

The University of Kentucky has been selected as the nationwide coordination center for a National Institutes of Health (NIH) initiative. Danelle Stevens-Watkins, Ph.D., will lead the National Institute on Drug Abuse (NIDA) Racial Equity Initiative as principal investigator.

13 Oct 2023

New technique to control severe bleeding increases risk of death, study finds

A new technique used to control severe bleeding in injured patients has been found to increase the risk of death, according to new research from the University of Aberdeen, in Scotland, which was led by University of Alabama at Birmingham trauma surgeon and professor Jan Jansen, Ph.D. Jansen was a surgeon and researcher in Aberdeen before moving to the United States in 2017.

13 Oct 2023

Ribbon-cutting ceremony marks the opening of Kentucky Children's four pediatric specialty clinics

On Tuesday, Oct. 10, a ribbon-cutting ceremony signified the official opening of Kentucky Children's Richmond Road, the new home of four pediatric specialty clinics.

13 Oct 2023

Experts call for action as male infertility increases worldwide

Infertility now affects one in six couples of reproductive age according to the World Health Organisation. About half the time, it originates from men.

13 Oct 2023

Opioid prescribing limits may not worsen patient experience after common surgeries

Worries that surgery patients would have a tougher recovery if their doctors had to abide by a five-day limit on opioid pain medication prescriptions didn't play out as expected, a new study finds.

13 Oct 2023

Nongenetic mechanisms play a role in lung cancer treatment resistance

In a recent study led by Ravi Salgia, M.D., Ph.D., the Arthur & Rosalie Kaplan Chair in Medical Oncology, a team of researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, and other institutions found that nongenetic mechanisms are important in lung cancer patients who develop a resistance to one cancer therapy.

13 Oct 2023

Study provides insights into atrial fibrillation detected after stroke

Worldwide, millions of stroke survivors undergo prolonged cardiac monitoring, leading to the discovery of atrial fibrillation, or irregular heartbeats, in up to 1.5 million of these patients each year.

13 Oct 2023

Early intervention with sublingual immunotherapy may lead to remission of peanut allergy

A three-year clinical trial funded by the National Institutes of Health and Food Allergy Research and Education (FARE) has shown that the sublingual immunotherapy, or SLIT, is safe in peanut-allergic children ages 1 to 4, with a greater likelihood of desensitization and remission the earlier the treatment began.

13 Oct 2023

OCT News and Research

Study links long COVID to gut inflammation and serotonin deficiency

Study shows outsized toll of dementia on family caregivers and finances

Study reveals previously unappreciated role for innate immune cells in early stages of TB infection

Two 'big gun' antibiotics may be safer for the kidneys than previously thought

Study highlights need for early intervention for behavioral problems

Moffitt Cancer Center researchers identify hidden target of ROS1 inhibitor lorlatinib

Live vaccinations found to be safe for pediatric organ transplant recipients

Medicare enrollees can switch coverage now. Here’s what’s new and what to consider.

Doctors abandon a diagnosis used to justify police custody deaths. It might live on, anyway.

Study identifies significant percentage of ventilated patients colonized with life-threatening pathogens

New insights into coronavirus E channel could lead to antiviral drugs

Calorie restriction may rejuvenate muscles and activate biological pathways for healthy aging

University of Kentucky selected as the nationwide coordination center for NIH racial equity initiative

New technique to control severe bleeding increases risk of death, study finds

Ribbon-cutting ceremony marks the opening of Kentucky Children's four pediatric specialty clinics

Experts call for action as male infertility increases worldwide

Opioid prescribing limits may not worsen patient experience after common surgeries

Nongenetic mechanisms play a role in lung cancer treatment resistance

Study provides insights into atrial fibrillation detected after stroke

Early intervention with sublingual immunotherapy may lead to remission of peanut allergy

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