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AEBP1 gene may play key role in the development and severity of liver disease

Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease, according to a study by Temple University, the Geisinger Obesity Institute and the Translational Genomics Research Institute, an affiliate of City of Hope.

18 Jul 2019

Study reveals how aggressive prostate cancer metastasizes by evading the immune system

Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the the immune system.

18 Jul 2019

Maternal proximity to oil and gas areas associated with congenital heart defects in babies

Mothers living near more intense oil and gas development activity have a 40-70% higher chance of having children with congenital heart defects compared to those living in areas of less intense activity, according to a new study from researchers at the Colorado School of Public Health.

18 Jul 2019

Researchers identify brain somatic mutations linked to Alzheimer's disease

Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease. Their findings were published in the journal Nature Communications last week.

18 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019

Researchers reveal molecular cause for severe multi-organ disorder

Three unrelated families on three continents (from continental Portugal, the United States and Brazil), all with healthy ancestors, had children with a very rare disease.

18 Jul 2019

Research team detects novel mechanism of inheritance

Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness.

18 Jul 2019

Cancer stem cells elude the body's immune cells by deactivating danger detector

Acute myeloid leukemia stem cells elude the body's immune cells by deactivating a danger detector. The underlying mechanisms and the potential new therapeutic approaches that this gives rise to have been detailed in the journal Nature by researchers from the University of Basel and University Hospital Basel in collaboration with colleagues in Germany.

18 Jul 2019

Light at last: why do more women develop Alzheimer’s disease?

Alzheimer’s disease (AD) is a leading cause of dementia in many older people, but it seems to affect twice as many women as men. Scientists have long tried to find out why this is so, and why it seems to follow a fast-track course in women.

18 Jul 2019

New research could help design algae that produces fuels and cleanup chemicals

It's a case of grand larceny that could lead to new fuels and cleanup chemicals. Ten species of red algae stole about 1 percent of their genes from bacteria to cope with toxic metals and salt stress in hot springs, according to a study in the journal eLife.

18 Jul 2019

Mathematical model helps quantify metastatic cell behavior

Cancer metastasis is a difficult stage to battle, especially if cancer cells are proliferating at a rapid pace. A new study reveals that metastatic cells change their shape to spread to other parts of the body. Researchers formulated a mathematical model to study metastatic cell behavior and similar cellular systems.

17 Jul 2019

Intermittent fasting may regulate blood glucose levels even without weight loss

New research suggests that intermittent fasting, cycling through periods of normal eating and fasting may regulate blood sugar (glucose) levels even when accompanied by little-to-no weight loss.

17 Jul 2019

Oxidative stress could play key role in the spreading of aberrant proteins in Parkinson's disease

Oxidative stress could be a driving force in the spreading of aberrant proteins involved in Parkinson's disease.

17 Jul 2019

Molecular switches may control lifespan and healthspan separately, genetic discovery suggests

Aging research indicates that better healthspan--the quality of life as we age--may be more important than lifespan.

17 Jul 2019

Empa researchers aim to fight unwanted biofilms

Some of us who are hospitalized are feeling worse rather than better. On average, seven percent of all patients in industrial countries are affected by "nosocomial" infections. In intensive care units, the risk increases even more. This can result in serious illnesses and life-threatening blood poisoning.

17 Jul 2019

Researchers identify chemical compounds that increase stability of haploid cell

Since the emergence of molecular genetics more than fifty years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes contained in somatic cells. Haploid cells are a powerful genetic tool to analyze gene function.

17 Jul 2019

Four young scientists receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award

The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $1 million to help address a critical shortage of funding for pediatric cancer research.

17 Jul 2019

Study: Causes of anorexia are likely metabolic and psychological

University of Otago, Christchurch researchers played a key role in new global research showing the causes of the eating disorder anorexia are likely metabolic as well as psychological.

17 Jul 2019

Study explores role of iron in over 900 diseases

In a series of early-stage studies examining genetic data from over 500,000 people, a team of international scientists, led by Imperial College London, explored the role that iron plays in over 900 diseases.

17 Jul 2019

Gene modulation goes wireless hacking the "boss gene"

Researchers from the University at Buffalo have successfully used technology to wirelessly tweak the functioning of a gene FGFR1. This gene is vital in the growth of embryos into adults. Their experiments were successful in the lab grown brain tissues and shows potential in therapeutics.

16 Jul 2019