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New defense mechanism makes lethal Salmonella strain resistant to viral infection

Scientists at the University of Liverpool and Harvard Medical School have discovered a new defence mechanism that makes a lethal strain of Salmonella resistant to viral infection.

1 Oct 2021

Damaging DNA builds up in the eyes to drive blinding age-related macular degeneration

Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the University of Virginia School of Medicine reveals.

1 Oct 2021

New approach reveals ‘protein partners’ that may contribute to unusual pathologies of COVID-19

COVID-19 not only causes symptoms characteristic of a typical respiratory disorder, but has also been known to trigger a wide range of other symptoms in people who had been infected, some lasting even long after individuals test negative for the virus.

30 Sep 2021

Protein network map uncovers previously unknown cancer drivers

In three studies from the Cancer Cell Map Initiative, researchers uncovered previously unknown interactions between proteins that drive cancer and combined this new data to generate a map of protein pathways informing cancer outcomes.

30 Sep 2021

Non-severe COVID-19 may elicit more durable memory B cell response than severe COVID-19

A recent study conducted by researchers from the US aimed to measure the impact of severity of COVID-19 on memory B cell response and characterize changes in the memory B cell compartment during the period between recovery and five months after symptom onset. This study is available on the bioRxiv* preprint server.

30 Sep 2021

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

A team of scientists from the USA and France has recently unveiled the mechanism of immune dysregulation in coronavirus disease 2019 (COVID-19) patients by analyzing the early-stage interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected epithelial cells and immune cells. The study is currently available on the bioRxiv* preprint server.

30 Sep 2021

Research points the way to identifying new precision treatments for cancer

Researchers at University of California San Diego and University of California San Francisco have mapped out how hundreds of mutations involved in two types of cancer affect the activity of discrete groups of proteins that are the ultimate actors behind the disease.

30 Sep 2021

Researchers discover how a genetic mutation in mice and monkeys interferes with viruses

A nationwide team of researchers, led by scientists at University of Utah Health and The Rockefeller University, has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola.

30 Sep 2021

Study reveals how to improve overall immune response against virally driven cancers

Blocking the PD-1 inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.

30 Sep 2021

New collaboration launched to accelerate the development of treatments for rare cancers

The University of Texas MD Anderson Cancer Center and the Rare Cancer Research Foundation today announced the launch of a collaboration designed to accelerate the development of new treatments for rare cancers by empowering all patients in the United States to contribute tumor samples directly to MD Anderson for translational research efforts.

30 Sep 2021

Researchers develop fluorescence quenching assay to probe the integrity of cell membrane coating

Cell membrane coated biomimetic nanoparticles (NPs) have been widely studied in nanomedicine because of their unique properties such as immune escaping, long blood circulation, specific molecular recognition and efficient cancer targeting, indicating a great potential in targeted cancer therapy.

30 Sep 2021

Gyros Protein Technologies introduces Gyrolab AAV9 Titer Kit to support AAV-based cell and gene therapy production

Gyros Protein Technologies AB today announced the introduction of Gyrolab® AAV9 Titer Kit for rapid determination of titer in AAV9 vector-based cell and gene therapy manufacturing.

From Gyros Protein Technologies AB 30 Sep 2021

Scientists use new technique to study the effects of reactive electrophilic drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation damages the protective myelin insulation around nerves, and the nerves themselves.

30 Sep 2021

Direct-to-consumer machine learning model incorrectly classifies rare, aggressive skin cancers

A new study has found that a direct-to-consumer machine learning model for detecting skin cancers incorrectly classified rare and aggressive cancers as low-risk.

30 Sep 2021

New drug combination effectively suppresses SARS-CoV-2 infection

More countries with greater resources are opening up for a more normal life. But COVID-19 and the SARS-CoV-2 virus are still a significant threat in large parts of the world.

30 Sep 2021

Researchers develop novel antibacterial material for wound dressing

Researchers at the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague) and the Technical University of Liberec in collaboration with researchers from the Institute of Microbiology of the CAS, the Department of Burns Medicine of the Third Faculty of Medicine at Charles University (Czech Republic), and P. J. Šafárik University in Košice (Slovakia) have developed a novel antibacterial material combining nonwoven nanotextile and unique compounds with antibacterial properties.

30 Sep 2021

The applications of nanomaterials against viral disease

The application of nanomaterials in the diagnosis, prevention, and treatment of viral diseases is reviewed in detail, highlighting areas of significant progress or stagnation from the past few decades.

30 Sep 2021

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

One of modern biologists' most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms.

30 Sep 2021

New system synthetically reconnects neural circuits using neuropeptides from Hydra

For two people to communicate in a loud, crowded room, they need to be standing side by side. The same is often true for neurons in the brain. But the same way a cell phone allows two people to communicate clearly across the room, new research at the Marine Biological Laboratory (MBL) opened up a new channel of communication in the worm C. elegans brain.

30 Sep 2021

Drop-off in urban park access impacted minorities and lower-income people during the pandemic

A new study found the use of outdoor parks and trails in urban areas of North Carolina declined during two summer months of 2020 – contrary to anecdotal reports of a spike in new users during the COVID-19 pandemic.

30 Sep 2021

B Cell News and Research

New defense mechanism makes lethal Salmonella strain resistant to viral infection

Damaging DNA builds up in the eyes to drive blinding age-related macular degeneration

New approach reveals ‘protein partners’ that may contribute to unusual pathologies of COVID-19

Protein network map uncovers previously unknown cancer drivers

Non-severe COVID-19 may elicit more durable memory B cell response than severe COVID-19

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

Research points the way to identifying new precision treatments for cancer

Researchers discover how a genetic mutation in mice and monkeys interferes with viruses

Study reveals how to improve overall immune response against virally driven cancers

New collaboration launched to accelerate the development of treatments for rare cancers

Researchers develop fluorescence quenching assay to probe the integrity of cell membrane coating

Gyros Protein Technologies introduces Gyrolab AAV9 Titer Kit to support AAV-based cell and gene therapy production

Scientists use new technique to study the effects of reactive electrophilic drugs

Direct-to-consumer machine learning model incorrectly classifies rare, aggressive skin cancers

New drug combination effectively suppresses SARS-CoV-2 infection

Researchers develop novel antibacterial material for wound dressing

The applications of nanomaterials against viral disease

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

New system synthetically reconnects neural circuits using neuropeptides from Hydra

Drop-off in urban park access impacted minorities and lower-income people during the pandemic

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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