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Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Clinical algorithm distinguishes between untreatable and treatable form of sudden cardiac arrest

Clinician-scientists in the Smidt Heart Institute at Cedars-Sinai developed a clinical algorithm that, for the first time, distinguishes between treatable sudden cardiac arrest and untreatable forms of the condition.

31 Mar 2022

Puerto Rican people with diabetes and high blood pressure show greater brain structural disruptions

The high rate of diabetes and high blood pressure combined in Puerto Rican people may be linked to structural changes in the brain, according to a study published in the March 30, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

31 Mar 2022

Study identifies a set of sporadic genetic mutations behind cavernous angioma

A rare type of brain blood vessel malformation known as a cavernous angioma affects more than one million Americans and carries a lifetime risk of stroke and seizures.

30 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

New antidiabetic substance preserves the activity of beta cells, prevents high blood glucose in mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

30 Mar 2022

Nanotherapies may benefit preterm babies with bronchopulmonary dysplasia

Very premature babies need extra oxygen and mechanical intervention to breathe, but this damages their lungs, causing a chronic lung disease called bronchopulmonary dysplasia (BPD).

30 Mar 2022

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

COMBINEDBrain puts advocacy groups in the driver's seat in the race to cure rare neurodevelopmental diseases. Patient advocacy foundations representing more than thirty rare genetic neurodevelopmental disorders join forces as part of COMBINEDBrain to make it faster to do research on their disorders.

30 Mar 2022

Dementia risk is high for people with atrial fibrillation, shows research

For people with atrial fibrillation, one of our most common cardiac disorders, dementia risk is elevated. This is shown by a University of Gothenburg thesis based on research at population level.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

Increased levels of a microRNA in type 2 diabetes have negative effect on insulin secretion

Researchers at Lund University have discovered increased levels of of a microRNA in type 2 diabetes, which has a negative effect on insulin secretion.

29 Mar 2022

Caffeine could be a therapeutic arsenal to alleviate some of the ADHD symptoms

Attention Deficit Hyperactivity Disorder, or ADHD, is a psychiatric pathology for which diagnosis has increased exponentially over the last 20 years.

29 Mar 2022

New tissue-clearing method could speed the study of many disease-related biological processes

Scientists at Scripps Research have unveiled a new tissue-clearing method for rendering large biological samples transparent.

29 Mar 2022

New test predicts sepsis well before blood clotting and organ failure

In a potential paradigm change for sepsis diagnostics, a new test predicted sepsis soon after infection in mice - well before blood clotting and organ failure - enabling early antibiotic treatment and markedly increased survival.

29 Mar 2022

Chronic low back pain associated with regional brain atrophy

Chronic low back pain is associated with reductions in brain volume in areas involved in pain processing, reports a study in PAIN, the official publication of the International Association for the Study of Pain (IASP). The journal is published in the Lippincott portfolio by Wolters Kluwer.

29 Mar 2022

FDA approves second COVID-19 booster dose for older and immunocompromised individuals

Today, the U.S. Food and Drug Administration authorized a second booster dose of either the Pfizer-BioNTech or the Moderna COVID-19 vaccines for older people and certain immunocompromised individuals.

29 Mar 2022

10-second videos of white blood cell motion improve the prediction of blood cancer relapse

In a new study from Vanderbilt University Medical Center, 10-second videos of white blood cell motion in the skin's microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.

29 Mar 2022

Blood News and Research

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Clinical algorithm distinguishes between untreatable and treatable form of sudden cardiac arrest

Puerto Rican people with diabetes and high blood pressure show greater brain structural disruptions

Study identifies a set of sporadic genetic mutations behind cavernous angioma

Role of SARS-CoV-2 S1 subunit in severe COVID-19

SARS-CoV-2 and pandemic chilblains

New antidiabetic substance preserves the activity of beta cells, prevents high blood glucose in mice

Nanotherapies may benefit preterm babies with bronchopulmonary dysplasia

COMBINEDBrain Biorepository: A comprehensive approach to speed research for rare diseases

Dementia risk is high for people with atrial fibrillation, shows research

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A ferritin nanoparticle candidate vaccine for COVID

Increased levels of a microRNA in type 2 diabetes have negative effect on insulin secretion

Caffeine could be a therapeutic arsenal to alleviate some of the ADHD symptoms

New tissue-clearing method could speed the study of many disease-related biological processes

New test predicts sepsis well before blood clotting and organ failure

Chronic low back pain associated with regional brain atrophy

FDA approves second COVID-19 booster dose for older and immunocompromised individuals

10-second videos of white blood cell motion improve the prediction of blood cancer relapse

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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