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3D-printed vaccine patch provides greater protection than a typical vaccine shot

Scientists at Stanford University and the University of North Carolina at Chapel Hill have created a 3D-printed vaccine patch that provides greater protection than a typical vaccine shot.

25 Sep 2021

The Lundquist Institute receives $5 million CIRM grant for a stem-cell focused program

The Lundquist Institute announced that it has received a generous $5 million, 5-year grant from the California Institute for Regenerative Medicine that will allow its PhD students, postdoctoral fellows and clinical fellows to pursue careers in stem cell biology and regenerative medicine.

24 Sep 2021

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

As mRNA-based SARS-CoV-2 vaccines are deployed to protect hundreds of millions of people across the world and point the way to end the deadly global COVID-19 pandemic, the University of Pennsylvania scientists whose prescient discovery science effort laid the foundation for swift vaccine development have been awarded the 2021 Lasker~DeBakey Clinical Medical Research Award.

24 Sep 2021

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Data from early clinical trials presented at the ESMO Congress 2021 suggest that new anticancer treatments are on the horizon, with a clear emphasis on precision medicine.

24 Sep 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Harmful side effects from a common chemotherapy drug could be the result of a single mutation, according to a study published in Cell Stem Cell.

24 Sep 2021

Ozone exposure linked to the development of Type 2 diabetes

Older Californians who live in communities with poor air quality, even those who engage - as recommended - in physical activities but do so outdoors, have a higher risk of Type 2 diabetes, a complex and chronic metabolic disorder caused by insulin resistance and cell dysfunction.

24 Sep 2021

Peter Adams and Gerald Shadel receive NIH grant to explore the link between aging and liver cancer

Sanford Burnham Prebys professor Peter D. Adams, Ph.D., who directs the Aging, Cancer and Immuno-oncology Program and Salk Institute professor Gerald Shadel, Ph.D., who directs the San Diego Nathan Shock Center of Excellence in the Basic Biology of Aging, have been awarded a grant from the NIH's National Institute on Aging for $13 million, funding a five-year project to explore the connection between aging and liver cancer.

24 Sep 2021

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

A new study presents initial results from a randomized, placebo-controlled phase 1/2 trial in Thailand.

24 Sep 2021

New 3D pancreatic cancer model could be used to develop and test targeted treatments

An international team of scientists have created a three-dimensional (3D) pancreatic cancer tumour model in the laboratory, combining a bioengineered matrix and patient-derived cells that could be used to develop and test targeted treatments.

24 Sep 2021

AI technique could lead to new ways to predict cancer prognosis and treatment response

Researchers and data scientists at UT Southwestern Medical Center and MD Anderson Cancer Center have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system.

24 Sep 2021

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

A new imaging technique for the detection of MALT lymphomas, malignant tumours of the lymphatic system, could probably save patients numerous gastroscopies. A study group of MedUni Wien achieved a high imaging accuracy by way of PET/MR and by using a PET Tracer directed against a certain cell receptor. The results are currently published in the top journal "Blood" of the American Society of Hematology.

24 Sep 2021

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Neuroinflammation can worsen outcomes in stroke, traumatic brain injury, or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson's, or Alzheimer's. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation.

24 Sep 2021

Study identifies master regulator behind the development of antibody-producing cells

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

24 Sep 2021

Researchers discover how Rift Valley fever virus enters cells

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle.

24 Sep 2021

Infections impact blood vessel repair within the meninges following TBI or other cerebrovascular injuries

Viral Infection Slows Blood Vessel Repair After TBI: Seven days after mTBI, the blood vessels (stained in red) in the tissues around the brain are not completely repaired. A marker for intact vessels was used (labeled in green) to distinguish fully functional blood vessels (yellow) from ones that are still damaged (red).McGavern Lab, NINDS

24 Sep 2021

Researchers identify two subtypes of metastatic prostate cancer

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease.

24 Sep 2021

Exploring the polymerase of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

May-Thurner anatomy common in patients with CTEPH, new study shows

Like highways, roads, and side streets, blood vessels in the human body come in different sizes, with a range of traffic-carrying capacities. These differences are critical to facilitating blood flow through tissues.

24 Sep 2021

New mutations enable gliomas to resist proven treatment, study shows

About one-third of all brain tumors are gliomas, cancerous growths that originate in the glial cells that surround and support neurons in the brain. The prognosis for patients with gliomas is not good, with the average survival time being 12-18 months.

24 Sep 2021

Mathematical constructions of SARS-CoV-2 action could help fine-tune prevention and treatment

Mathematical constructions of the action of SARS-CoV-2 and its multiple spikes, which enable its success at infecting cells, can give vaccine developers and pharmaceutical companies alike a more precise picture of what the virus is doing inside us and help fine tune prevention and treatment, mathematical modelers say.

23 Sep 2021

B Cell News and Research

3D-printed vaccine patch provides greater protection than a typical vaccine shot

The Lundquist Institute receives $5 million CIRM grant for a stem-cell focused program

Penn scientists win 2021 Lasker Award for the discovery of therapeutic mRNA technology

Promising data from early clinical trials of new anticancer therapies presented at ESMO Congress 2021

Cardiotoxic effects of common chemotherapy drug could be prevented

Ozone exposure linked to the development of Type 2 diabetes

Peter Adams and Gerald Shadel receive NIH grant to explore the link between aging and liver cancer

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

New 3D pancreatic cancer model could be used to develop and test targeted treatments

AI technique could lead to new ways to predict cancer prognosis and treatment response

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Study identifies master regulator behind the development of antibody-producing cells

Researchers discover how Rift Valley fever virus enters cells

Infections impact blood vessel repair within the meninges following TBI or other cerebrovascular injuries

Researchers identify two subtypes of metastatic prostate cancer

Exploring the polymerase of poxviruses at an atomic level

May-Thurner anatomy common in patients with CTEPH, new study shows

New mutations enable gliomas to resist proven treatment, study shows

Mathematical constructions of SARS-CoV-2 action could help fine-tune prevention and treatment

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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