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Delayed lactate measurements in sepsis patients increase risk of in-hospital death

The rising incidence of sepsis, a leading cause of in-hospital death, has prompted the Centers for Medicare and Medicaid Services to issue protocols known as care bundles to standardize and improve sepsis care.

25 May 2018

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that by helping to form clots within tumors, immune cells that flock to a particular type of lung cancer are actually building a foundation for the tumor to spread within the body.

25 May 2018

New consensus statement outlines evidence-based medical opinion on abusive head trauma

Abusive head trauma, a medical diagnosis of infants and young children who suffer from inflicted intracranial and associated spinal injuries, is often misrepresented in legal proceedings of child abuse, according to a consensus statement supported by nine pediatric and radiology international organizations published in Pediatric Radiology.

25 May 2018

Scientists report new strategy for fighting bacteria

Antimicrobial resistance is a major medical problem worldwide, impacting both human health and economic well-being.

24 May 2018

Researchers take important step toward finding protein biomarkers during cancer surgery

Isabelle Fournier and her team are out to change surgical oncology. "Better surgery is associated with better prognosis and higher survival," said Fournier, a professor at the University of Lille and co-director of a proteomics center of INSERM, the French national institute of health.

24 May 2018

NIH commences first-in-human trial evaluating experimental treatment for Ebola

A first-in-human trial evaluating an experimental treatment for Ebola virus disease has begun at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

24 May 2018

UD researchers examine connection between DNA replication in HPV and cancer

A pair of researchers from the University of Delaware Department of Medical and Molecular Sciences are investigating genetic variations in DNA replication of human papillomaviruses and its correlation with HPV-related cancers.

23 May 2018

Zika detection breakthrough by University of Queensland

A cheap and effective tool that could save lives by helping health authorities target mosquitos infected with Zika virus has been developed by researchers from the University of Queensland and colleagues in Brazil.

23 May 2018

Scientists develop lab-based system to study mechanisms of common liver disease

Scientists have developed a lab-based system for studying the most common type of liver disease, paving the way for research into new therapies.

23 May 2018

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.

23 May 2018

Study shows bacteria behave differently in humans compared to the lab

A recent study has shown that deadly bacteria such as Pseudomonas aeruginosa behave differently in the humans, compared to a laboratory setting.

23 May 2018

Researchers develop injectable bandage to stop fatal blood loss, activate wound healing

While several products are available to quickly seal surface wounds, rapidly stopping fatal internal bleeding has proven more difficult.

22 May 2018

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris - an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group - is addressing this very question.

22 May 2018

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of predators such as foxes, cats or snakes despite having never seen them.

22 May 2018

Staying up all night, sleeping all day can swiftly impact over 100 proteins in the blood

Staying awake all night and sleeping all day for just a few days can disrupt levels and time of day patterns of more than 100 proteins in the blood, including those that influence blood sugar, energy metabolism, and immune function, according to new University of Colorado Boulder research published in the journal PNAS this week.

22 May 2018

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Planning a trip to Mars? You'll want to remember your anti-radiation pills. NASA and private space companies like SpaceX plan to send humans to the red planet within the next 15 years--but among the major challenges facing future crewed space missions is how to protect astronauts from the dangerous cosmic radiation of deep space.

22 May 2018

Researchers uncover clues to early lung transplant failure

Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung.

22 May 2018

New LIVE scoring tool effectively predicts future risk of hospitalization for COPD patients

Researchers have developed a new tool that utilizes basic laboratory tests to effectively identify patients with chronic obstructive pulmonary disease who are at high risk of being hospitalized due to a flare up of the condition.

22 May 2018

Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study

Anaplastic thyroid cancer is almost uniformly fatal, with an average lifespan of about 5 months after diagnosis.

22 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

Laboratory News and Research

Delayed lactate measurements in sepsis patients increase risk of in-hospital death

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

New consensus statement outlines evidence-based medical opinion on abusive head trauma

Scientists report new strategy for fighting bacteria

Researchers take important step toward finding protein biomarkers during cancer surgery

NIH commences first-in-human trial evaluating experimental treatment for Ebola

UD researchers examine connection between DNA replication in HPV and cancer

Zika detection breakthrough by University of Queensland

Scientists develop lab-based system to study mechanisms of common liver disease

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

Study shows bacteria behave differently in humans compared to the lab

Researchers develop injectable bandage to stop fatal blood loss, activate wound healing

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Staying up all night, sleeping all day can swiftly impact over 100 proteins in the blood

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Researchers uncover clues to early lung transplant failure

New LIVE scoring tool effectively predicts future risk of hospitalization for COPD patients

Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

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