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Risk factors for Alzheimer's disease

Alzheimer's disease has joined cancer at the top of the list of feared diagnoses, and although Alzheimer's does have the potential to devastate millions of patients and families, there are reasons for hope - and possibly opportunities to reduce risk or alter the course of disease progression, according to Keith Black, MD, professor and chair of the Department of Neurosurgery at Cedars-Sinai.

26 Nov 2013

Researchers reveal why some breast cancer cells are resistant to chemotherapy

Researchers at the UNC School of Medicine, working with cell lines in a lab, have discovered why some of the most aggressive and fatal breast cancer cells are resistant to chemotherapy, and UNC scientists are developing ways to overcome such resistance.

26 Nov 2013

SillaJen executes definitive merger agreement to acquire Jennerex

SillaJen, Inc., a privately-held biotherapeutics and contract research company focused on the development of targeted biological products for cancer, announced today that it had executed a definitive merger agreement to acquire San Francisco-based Jennerex, Inc.

26 Nov 2013

Seed grants support cancer diagnosis and treatment, vascular health research

Five teams of scientists earned research seed grants awarded this year by the John S. Dunn Foundation. The awards support new collaborations by researchers at Rice University's BioScience Research Collaborative (BRC) and their partners at other institutional members of the Gulf Coast Consortia (GCC).

26 Nov 2013

Researchers identify new form of treatment for brain tumor

Glioblastoma is one of the most ominous brain tumors. Despite aggressive surgery, radiation and chemotherapy the outcome of this disease is almost always fatal.

26 Nov 2013

Cocktail eradicates animals' brain tumors

A novel immune-boosting drug combination eradicates brain cancer in mice, according to a study in The Journal of Experimental Medicine.

26 Nov 2013

Phase 1/2 clinical trial data for VAL-083 in glioblastoma is presented at 18th Annual SNO meeting

DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) ("DelMar" and "DelMar Pharma") today announced the presentation of interim data from a Phase 1/2 clinical trial for VAL-083 in recurrent glioblastoma (GBM) at the 4th Quadrennial Meeting of the World Federation of Neuro-Oncology (WFNO) being held in conjunction with the 18th Annual Society for Neuro-Oncology (SNO) meeting in San Francisco.

25 Nov 2013

Patients with symptom clusters after surgery for esophageal cancer have increased mortality risk

A new study has found that several months after surgery for esophageal cancer, different symptoms cluster together in different types of patients. In addition, patients with certain symptom clusters have an increased risk of dying from their disease.

25 Nov 2013

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Bayer HealthCare and Onyx Pharmaceuticals, Inc., an Amgen subsidiary, today announced that the U.S. Food and Drug Administration has approved a supplemental New Drug Application for the oral multi-kinase inhibitor NEXAVAR (sorafenib) tablets for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma refractory to radioactive iodine treatment.

23 Nov 2013

Mouse study highlights importance of microorganisms in optimal cancer treatment outcomes

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22 Nov 2013

Researchers study role of small non-coding RNAs expressed in the human male germline

Researchers from the Bellvitge Biomedical Research Institute in Barcelona, Spain, have studied the role of a peculiar class of small non-coding RNAs that are mainly expressed in the human male germline.

22 Nov 2013

Neurosurgeons use novel technique to visualize the brain's delicate anatomy prior to surgery

Neurosurgeons at UC San Diego Health System are using a new approach to visualize the brain's delicate anatomy prior to surgery. The novel technique allows neurosurgeons to see the brain's nerve connections thus preserving and protecting critical functions such as vision, speech and memory. No needles, dyes or chemicals are needed to create the radiology scan. The main imaging ingredient? Water.

22 Nov 2013

Combinatory therapy may be effective in suppressing drug resistance in treatment of melanoma

Stand Up To Cancer (SU2C), the charitable initiative supporting ground-breaking research aimed at getting new cancer treatments to patients in an accelerated timeframe, announces that the Allan H. (Bud) and Sue Selig Stand Up To Cancer Melanoma Innovative Research Grant Recipient Roger S. Lo, M.D., Ph.D., associate professor in the Department of Medicine at the Jonsson Comprehensive Cancer Center of the University of California, Los Angeles (UCLA) has published two studies in Cancer Discovery, a journal of the American Association for Cancer Research which indicate that treatment using combinatory therapy may be effective in suppressing drug resistance in the treatment of melanoma.

21 Nov 2013

Research: New drugs show ability to rapidly shrink melanoma tumors

Melanoma is the deadliest form of skin cancer, killing more than 8,000 in the U.S. each year. Approximately 40 percent of advanced melanoma tumors are driven to grow by the presence of mutations in a gene known as the BRAF gene.

21 Nov 2013

New technique can diagnose cancer with high degree of accuracy, say researchers

A team of researchers from UCLA and Harvard University have demonstrated a technique that, by measuring the physical properties of individual cells in body fluids, can diagnose cancer with a high degree of accuracy.

21 Nov 2013

Type 2 diabetes cytokine elevation places teeth at risk

Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.

21 Nov 2013

Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

The development of a probe to measure the body's immune function could lead to more accurate, individualized doses for cancer patients prescribed nanoparticle-based drugs, according to research conducted at the University of North Carolina.

21 Nov 2013

Smoking influences survival of nasopharyngeal carcinoma patients

Survivors of nasopharyngeal carcinoma who are former or current smokers are more likely to have their disease progress, relapse, or spread, and are more likely to die of their disease, compared with survivors of nasopharyngeal carcinoma who have never smoked, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

21 Nov 2013

Findings show how cancer and aging are tightly interconnected

Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic changes describe heritable alterations caused by mechanisms other than by changes in DNA sequence. The discovery, published in the February 2014 issue of Epigenetics, illustrates how cancer and aging are tightly interconnected processes by identifying epigenetic alterations present in the normal aging breast that may increase disease risk in cancer-free individuals.

21 Nov 2013

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

What we are trying to do is take a cancer model like the PDX model (patient-derived tumor xenograft), which is a human-derived cancer growing in an in vivo model and apply radiation to that model.

From Xstrahl 20 Nov 2013

Tumor News and Research

Risk factors for Alzheimer's disease

Researchers reveal why some breast cancer cells are resistant to chemotherapy

SillaJen executes definitive merger agreement to acquire Jennerex

Seed grants support cancer diagnosis and treatment, vascular health research

Researchers identify new form of treatment for brain tumor

Cocktail eradicates animals' brain tumors

Phase 1/2 clinical trial data for VAL-083 in glioblastoma is presented at 18th Annual SNO meeting

Patients with symptom clusters after surgery for esophageal cancer have increased mortality risk

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Mouse study highlights importance of microorganisms in optimal cancer treatment outcomes

Researchers study role of small non-coding RNAs expressed in the human male germline

Neurosurgeons use novel technique to visualize the brain's delicate anatomy prior to surgery

Combinatory therapy may be effective in suppressing drug resistance in treatment of melanoma

Research: New drugs show ability to rapidly shrink melanoma tumors

New technique can diagnose cancer with high degree of accuracy, say researchers

Type 2 diabetes cytokine elevation places teeth at risk

Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

Smoking influences survival of nasopharyngeal carcinoma patients

Findings show how cancer and aging are tightly interconnected

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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