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CDISC and C-Path develop new standard to streamline data for animal rule studies

The Critical Path Institute (C-Path) and CDISC are pleased to announce the release of a global Foundational Standard that describes how to represent data for the natural history and efficacy studies conducted in animals submitted to applications under the U.S. Food and Drug Administration (FDA) regulations commonly known as the Animal Rule.

16 Oct 2019

New initiative aims to use artificial intelligence to identify early drug candidates

Insilico Medicine, in collaboration with ChemDiv, Inc., launched a drug discovery initiative that aims to use the power of artificial intelligence for screening chemistry space with newly designed compounds.

16 Oct 2019

Machine learning system may offer warnings about negative side effects of drug-drug interactions

The more medications a patient takes, the greater the likelihood that interactions between those drugs could trigger negative side effects, including long-term organ damage and even death.

15 Oct 2019

Inactive receptor prevents cancer drugs from reactivating the immune system

The aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose.

15 Oct 2019

Amyloid-β protein misfolding proves to be strong risk prediction marker for Alzheimer's

In symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicated a considerably higher risk of Alzheimer's disease - up to 14 years before a clinical diagnosis was made.

15 Oct 2019

Study explains why some people who take heart medication develop sore, aching muscles

A study from McMaster University has found a potential mechanism explaining why some people who take drugs to lower their cholesterol develop sore, aching muscles.

15 Oct 2019

CRISPR helps find difficult to detect cancer cells

Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in the cancer cells that can make the cells invisible to the immune system normally. Some of the cancers cells can now develop other ways to disguise themselves from being killed by the immune system.

15 Oct 2019

New class of drugs could prevent cancer from becoming resistant to treatment

Scientists at Massey University in New Zealand have taken the first step towards a new class of drug that could stop cancer from becoming resistant to treatment. Treatment resistance is a serious problem to the successful treatment of cancer patients because it leads to cancer returning and becoming harder to treat.

15 Oct 2019

New federal grant to expand outreach to help underserved communities battle opioid epidemic

According to government data, more than 70,000 Americans died in 2017 by overdosing on opioids. In response to the opioid crisis, the US Department of Health and Human Services outlined several key priorities, including improved treatment access, use of overdose-reversing drugs and improved pain management strategies.

15 Oct 2019

UCLA researchers discover new way to eliminate leukemia stem cells

The introduction of the drug imatinib in 2001 revolutionized the treatment of a type of cancer called chronic myelogenous leukemia. In more than 80% of people with CML who received the drug, the disease went into complete remission.

15 Oct 2019

CANDO drug discovery platform focuses on finding new medications for mental illnesses

An estimated 46.6 million U.S. adults struggle with mental illnesses, such as anxiety disorder, according to the National Institute of Mental Health. About half of millennials and 75% of Gen-Zers report having quit jobs for mental health reasons.

15 Oct 2019

Think ‘Medicare for All’ is the only democratic health plan? Think again

If you tuned in for the first five nights of the Democratic presidential debates, you might think "Medicare for All" and providing universal care are the only health care ideas Democrats have.

15 Oct 2019

How dementia spreads: new study says it’s through neural networks

Scientists have found out a way to forecast the spread of brain atrophy, using prior research that shows how brain networks connect with each other to form a continuously linked pathway.

14 Oct 2019

Rapid and sensitive tracking of fat molecules in the body

Fats have earned a bad name as the source of all that is wrong with our hearts and blood vessels, not to mention our appearance. The dysfunctional handling of lipids or fats in the body is deeply involved in a multitude of metabolic upsets, such as obesity and cancer.

14 Oct 2019

Signs of aging detected by a simple walking test at age 45

A new study has shown that the speed at which persons over 45 years of age walk could be an indicator of their brain and body age. The team of researchers from Duke University found that persons who walked slowly were more likely to have “accelerated aging” compared to those who walked faster.

14 Oct 2019

Drugs News and Research

CDISC and C-Path develop new standard to streamline data for animal rule studies

New initiative aims to use artificial intelligence to identify early drug candidates

Machine learning system may offer warnings about negative side effects of drug-drug interactions

Inactive receptor prevents cancer drugs from reactivating the immune system

Amyloid-β protein misfolding proves to be strong risk prediction marker for Alzheimer's

Study explains why some people who take heart medication develop sore, aching muscles

CRISPR helps find difficult to detect cancer cells

New class of drugs could prevent cancer from becoming resistant to treatment

New federal grant to expand outreach to help underserved communities battle opioid epidemic

UCLA researchers discover new way to eliminate leukemia stem cells

CANDO drug discovery platform focuses on finding new medications for mental illnesses

Think ‘Medicare for All’ is the only democratic health plan? Think again

How dementia spreads: new study says it’s through neural networks

Rapid and sensitive tracking of fat molecules in the body

Signs of aging detected by a simple walking test at age 45

Default response to spinal disc injuries can be temporarily stopped to allow for better treatment

Highly sensitive method can 'track' fat metabolism

New Penn Medicine study unravels the early makings of an exhausted T cell

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

'Tricked' bacteria open door to new antimicrobial therapies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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