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Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly focusing on the effects of the probiotic Lacticaseibacillus paracasei Zhang (LCZ) on the cholesterol-lowering drug lovastatin.

28 Aug 2025

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

A tiny fish with transparent embryos is helping University of California, Davis, researchers shed light on how exposure to crude oil and flame retardants can affect behavior, skeletal growth, cardiac health and other internal functions in offspring and subsequent generations.

28 Aug 2025

Chronic neuron overactivation may drive Parkinson's disease progression

Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die.

28 Aug 2025

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Researchers from Japan discover that glucagon-like peptide-2 (GLP-2) analogs can deeply and beneficially reshape the intestinal environment.

27 Aug 2025

Why Salmonella Dublin poses a food safety threat in beef and dairy

The study on Salmonella Dublin highlights its genomic similarities and resistance traits, raising concerns for food safety and antimicrobial resistance.

27 Aug 2025

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with substantial morbidity and mortality.

27 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

People with lower interleukin-6 activity have a reduced risk of cardiovascular diseases, a new LMU study reveals.

26 Aug 2025

Groundbreaking method captures microbial memory at the earliest stages of colony growth

Bacteria aren't just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a "memory" of their past environments-passing it down through generations-before eventually forgetting.

26 Aug 2025

Natural compound forskolin enhances chemotherapy effectiveness against aggressive leukemia

A natural compound could help fight aggressive leukaemia and amplify the effect of chemotherapy drugs.

26 Aug 2025

Investigating toxicity of common bisphenol replacements in food packaging

Chemicals used to replace bisphenol A (BPA) in food packaging can trigger potentially harmful effects in human ovarian cells, according to McGill University researchers.

26 Aug 2025

Probiotics limit the spread of drug-resistant genes in preemies

Study reveals probiotics help preterm infants develop healthier gut microbiomes, reducing multidrug-resistant bacteria and enhancing neonatal care outcomes.

26 Aug 2025

Common cold may offer temporary protection against SARS-CoV-2 infection

A new study led by researchers at National Jewish Health has found that recent infection with the common cold - often caused by rhinoviruses - may offer temporary protection against infection with SARS-CoV-2, the virus that causes COVID-19.

25 Aug 2025

Genetics and diet work together to shape daily rhythms of fat metabolism

Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism.

25 Aug 2025

AI tool reveals how TB drugs kill bacteria at the molecular level

Tuberculosis (TB) is the world's deadliest infectious disease—and one of the hardest to cure. Standard treatment requires a cocktail of multiple drugs over at least six months, and one in five patients have a type of TB that resists these first-line medications.

25 Aug 2025

African swine fever vaccine shows variable protection across virus strains

An international team of scientists has found that a promising African swine fever (ASF) vaccine can protect pigs against some strains of the virus but offers little or no protection against others. The findings point to the need for region-specific vaccines to tackle one of the world's most devastating animal diseases.

25 Aug 2025

New molecular mechanism offers hope for treating depression in the elderly

Major depressive disorder (MDD) is one of the most common psychiatric illnesses worldwide, but its molecular causes have still not been clearly identified.

25 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025