Genetic Engineering News and Research

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Researchers uncover promising targets for development of drugs against leishmaniasis

Brazilian researchers at the University of São Paulo's Bioscience Institute (IB-USP) are starting to unravel the molecular mechanisms by which the parasite that causes cutaneous leishmaniasis manages to circumvent the host organism's defenses and infect new cells.

5 Oct 2017

Brain wiring directly impacts performance of simple and complex tasks

The way a person's brain is "wired" directly impacts how well they perform simple and complex tasks, according to a new study from researchers at Rice University.

5 Oct 2017

Study uses ferret model to elucidate key mechanisms for gyrus formation

The human brain is highly developed with higher functions compared to other animals, thanks to which humans are believed to have acquired special abilities. One of the important factors considered to contribute to the development of the brain is the gyrus, the fold on the cerebral cortex surface.

5 Oct 2017

Study compares long-term metabolic effects of conventional and genetically-modified soybean oil

Researchers at the University of California, Riverside have tested a genetically-modified (GM) soybean oil used in restaurants and found that while it induces less obesity and insulin resistance than conventional soybean oil, its effects on diabetes and fatty liver are similar to those of conventional soybean oil.

4 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017

GM mosquitoes can have altered microbiota that suppresses human malaria-causing parasites

WHAT: Using genetically modified (GM) mosquitoes to reduce or prevent the spread of infectious diseases is a new but rapidly expanding field of investigation.

30 Sep 2017

NTU Singapore, KAIST scientists discover new mechanism that causes Parkinsonian symptoms

Scientists from Nanyang Technological University, Singapore and the Korea Advanced Institute of Science & Technology have identified a new mechanism that causes the hallmark symptoms of Parkinson's disease, namely tremors, rigidity, and loss of voluntary movement.

28 Sep 2017

Scientists gain insight into how Ebola virus uses the body's defenses to speed up infection

Scientists from The University of Texas Medical Branch at Galveston have gained new insight into how the Ebola virus uses the body's natural defenses to speed the rate of infection and unleash its lethal disease, according to a new report in mBio.

26 Sep 2017

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

Scientists at Rutgers University-New Brunswick used a genetic engineering technique for the first time to create brain cells from the blood cells of individuals in a three-generation family with Tourette syndrome to help determine what causes the disease.

25 Sep 2017

New discovery about high-risk Alzheimer’s gene suggests potential therapeutic target

Nearly a quarter century ago, a genetic variant known as ApoE4 was identified as a major risk factor for Alzheimer's disease- one that increases a person's chances of developing the neurodegenerative disease by up to 12 times.

21 Sep 2017

Researchers assess self-monitoring of blood glucose behavior among diabetes patients in China

Researchers in China who assessed self-monitoring of blood glucose behavior among nearly 19,000 patients with type 2 diabetes treated with oral medications reported very low SMBG rates both before and after the patients began treatment with basal insulin, although the data showed an increase in mean SMBG frequency after 6 months and the percentage of patients who never monitored their blood glucose decreased.

21 Sep 2017

Scientists find a way to convert “bad body fat” to “good fat”

Researchers have found that the unhealthy fat in the body called “white fat” could be converted to a healthier fat by blocking a special protein. This could help fight the obesity epidemic they speculate. The report was published in the journal Cell Reports.

19 Sep 2017

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Johns Hopkins researchers report they have genetically engineered mice that display many of the behavioral hallmarks of human bipolar disorder, and that the abnormal behaviors the rodents show can be reversed using well-established drug treatments for bipolar disorder, such as lithium.

18 Sep 2017

Breakthrough research allows scientists to program cells like computers for battling against diseases

Cells can be programmed like a computer to fight cancer, influenza, and other serious conditions - thanks to a breakthrough in synthetic biology by the University of Warwick.

18 Sep 2017

Research unravels how stem cells in the ovaries may be harnessed to revolutionize fertility treatments

About 13 years ago, Northeastern professor Jonathan Tilly, a reproductive biologist, made a discovery that challenged everything scientists thought they knew about female reproduction. The long-held belief that mammals were born with a set number of eggs -- and no ability to create new ones -- was wrong.

15 Sep 2017

KU Leuven researchers find that humans have lost ancient defense mechanism to combat viruses

Insects and plants have an important ancient defense mechanism that helps them to fight viruses. This is encoded in their DNA. Scientists have long assumed that vertebrates - including humans - also had this same mechanism. But researchers at KU Leuven, Belgium, have found that vertebrates lost this particular asset in the course of their evolution.

15 Sep 2017

Study uncovers how inflammation contributes to key feature of diabetes

A new study by researchers at the University of Maryland School of Medicine has uncovered how inflammation contributes to a key feature of diabetes, the body's inability to metabolize glucose, a condition known as insulin resistance.

12 Sep 2017

Combination treatment provides positive results for people with advanced melanoma

In a two-year UCLA-led study, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC.

8 Sep 2017

Genetic Engineering News and Research

Researchers uncover promising targets for development of drugs against leishmaniasis

Brain wiring directly impacts performance of simple and complex tasks

Study uses ferret model to elucidate key mechanisms for gyrus formation

Study compares long-term metabolic effects of conventional and genetically-modified soybean oil

Scientists manipulate living cells to produce fluorinated bioplastics

“Chemical surgery” on embryos to free them of a gene causing thalassemia

Researchers produce fluorinated molecules in living cells

GM mosquitoes can have altered microbiota that suppresses human malaria-causing parasites

NTU Singapore, KAIST scientists discover new mechanism that causes Parkinsonian symptoms

Scientists gain insight into how Ebola virus uses the body's defenses to speed up infection

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

New discovery about high-risk Alzheimer’s gene suggests potential therapeutic target

Researchers assess self-monitoring of blood glucose behavior among diabetes patients in China

Scientists find a way to convert “bad body fat” to “good fat”

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Breakthrough research allows scientists to program cells like computers for battling against diseases

Research unravels how stem cells in the ovaries may be harnessed to revolutionize fertility treatments

KU Leuven researchers find that humans have lost ancient defense mechanism to combat viruses

Study uncovers how inflammation contributes to key feature of diabetes

Combination treatment provides positive results for people with advanced melanoma

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